Zobrazeno 1 - 10
of 10
pro vyhledávání: '"Akiko Mori-Abe"'
Autor:
Chika Ohshima, Masahide Ohmichi, Hirohisa Kurachi, Akira Ohishi, Kazuhiro Takahashi, Botao Du, Maki Saitoh, Tsuyoshi Ohta, Masakazu Doshida, Naohiro Tezuka, Akiko Mori-Abe, Jun Kawagoe, Hideki Igarashi, Toshifumi Takahashi
Publikováno v:
Journal of Endocrinology. 183:605-615
Although estrogen is known to protect against β-amyloid (Aβ)-induced neurotoxicity, the mechanisms responsible for this effect are only beginning to be elucidated. In addition, the effect of raloxifene on Aβ-induced neuro-toxicity remains unknown.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::691125ba88f09588fb85466f3f9fae79
https://doi.org/10.1677/joe.1.05775
https://doi.org/10.1677/joe.1.05775
Autor:
Satoru Kyo, Seiji Mabuchi, Jun Kawagoe, Chika Ohshima, Hirohisa Kurachi, Maki Saitoh, Masahide Ohmichi, Masaki Inoue, Kazuhiro Takahashi, Akiko Kimura, Hideki Igarashi, Toshifumi Takahashi, Tsuyoshi Ohta, Akiko Mori-Abe, Botao Du
Publikováno v:
Journal of Biological Chemistry. 278:43363-43372
The mechanism by which raloxifene acts in the chemoprevention of breast cancer remains unclear. Because telomerase activity is involved in estrogen-induced carcinogenesis, we examined the effect of raloxifene on estrogen-induced up-regulation of telo
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::7df3e2b11ba83d5163d671c96e7cc3ff
https://doi.org/10.1074/jbc.m304363200
https://doi.org/10.1074/jbc.m304363200
Autor:
Botao Du, Kazuhiro Takahashi, Masaki Yoshida, Seiji Tsutsumi, M Toya, Jun Kawagoe, Hirohisa Kurachi, Akiko Mori-Abe, Toshifumi Takahashi, K Nakahara, Masahide Ohmichi
Publikováno v:
Journal of Endocrinology. 178:417-426
Proliferation of vascular smooth muscle cells (VSMC) plays a major role as an initiating event of atherosclerosis. Although estrogen directly inhibits the proliferation of VSMC, the mechanism has not been firmly established. In addition, the effect o
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::219ad96eb6207b84047d370cfcdcd470
https://doi.org/10.1677/joe.0.1780417
https://doi.org/10.1677/joe.0.1780417
Autor:
Seiji Tsutsumi, Hirohisa Kurachi, Keiko Takata, Masahide Ohmichi, Kazuhiro Takahashi, Tsuyoshi Ohta, Akiko Mori-Abe, Jun Kawagoe
Publikováno v:
Menopause (New York, N.Y.). 14(4)
Objective: To examine the effect of raloxifene on the endothelial dysfunction caused by surgical menopause. Design: Ten premenopausal women who underwent gynecological surgery with ovariectomy were divided into two groups. Five participants used ralo
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::3d7a9b1c35ffdf512f7e060996f69ec7
https://pubmed.ncbi.nlm.nih.gov/17242632
https://pubmed.ncbi.nlm.nih.gov/17242632
Autor:
Hirohisa Kurachi, Toshifumi Takahashi, Kazuhiro Takahashi, Botao Du, Tsuyoshi Ohta, Jun Kawagoe, Akiko Mori-Abe, Seiji Tsutsumi, Masakazu Doshida, Maki Saitoh-Sekiguchi, Masahide Ohmichi
Publikováno v:
The Journal of biological chemistry. 281(34)
Vascular endothelial senescence is involved in human atherosclerosis. Telomerase activity is known to be critical in cellular senescence and its level is modulated by regulation of telomerase catalytic subunit (telomerase reverse transcriptase (TERT)
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::95b292bb1af4844c6a2f6bf5495cb33d
https://pubmed.ncbi.nlm.nih.gov/16798746
https://pubmed.ncbi.nlm.nih.gov/16798746
Autor:
Masakazu Doshida, Maki Saitoh, Tsuyoshi Ohta, Akiko Mori-Abe, Masahide Ohmichi, Jun Kawagoe, Kazuhiro Takahashi, Hideki Igarashi, Toshifumi Takahashi, Hirohisa Kurachi, Seiji Tsutsumi, Botao Du
Publikováno v:
Endocrinology. 146(11)
The mechanism of medroxyprogesterone acetate (MPA)-induced cell proliferation in human breast cancer cells remains elusive. We examined the mechanism by which MPA affects the cyclin D1 expression in progesterone receptor (PR)-positive T47D human brea
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::0d24ac3efb82c7c81fa9d52fed4eabea
https://pubmed.ncbi.nlm.nih.gov/16123159
https://pubmed.ncbi.nlm.nih.gov/16123159
Autor:
Hirohisa Kurachi, Sayaka Miura, Akiko Mori-Abe, Masahide Ohmichi, Jun Kawagoe, Keiko Takata, Kazuhiro Takahashi
Publikováno v:
Gynecologic and obstetric investigation. 60(3)
Background/Aims: Aortic stiffness, determined by pulse wave velocity (PWV), is an independent marker of cardiovascular risk. PWV is mainly influenced by age-associated alterations in arterial wall structure and blood pressure. The present study was c
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::43eb4a9d3b1742222048743be12ca61e
https://pubmed.ncbi.nlm.nih.gov/15980658
https://pubmed.ncbi.nlm.nih.gov/15980658
Autor:
Jun Kawagoe, Kazuhiro Takahashi, Akira Oishi, Akiko Mori-Abe, Toshifumi Takahashi, Noriyuki Inaba, Reiko Otsu, Masahide Ohmichi, Hirohisa Kurachi, Yoshiko Mochizuki
Publikováno v:
Biochemical and biophysical research communications. 324(1)
We report the novel observation that medroxyprogesterone acetate (MPA) attenuates the induction by 17beta estradiol (E2) of both nitric oxide (NO) production and endothelial nitric oxide synthase (eNOS) activity in human umbilical vein endothelial ce
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a41dffddd64493f9bd7f93c7e35de0b8
https://pubmed.ncbi.nlm.nih.gov/15465001
https://pubmed.ncbi.nlm.nih.gov/15465001
Autor:
Keiko Takata, Maki Murakami, Kazuhiro Takahashi, Akiko Mori-Abe, Eiichi Tanaka, Masahide Ohmichi, Hirohisa Kurachi, Jun Kawagoe
Publikováno v:
Maturitas. 49(2)
Objectives: Carotid intima-media thickness (IMT) is an appropriate intermediate end point to investigate clinically relevant effects on atherogenesis. The study objective was to clarify whether long-term hormone replacement therapy (HRT) modifies the
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::359621dc47efec40d01d5dc3673ce716
https://pubmed.ncbi.nlm.nih.gov/15474762
https://pubmed.ncbi.nlm.nih.gov/15474762
Autor:
Botao Du, Masahide Ohmichi, Kazuhiro Takahashi, Jun Kawagoe, Chika Ohshima, Hideki Igarashi, Akiko Mori-Abe, Maki Saitoh, Tsuyoshi Ohta, Akira Ohishi, Masakazu Doshida, Naohiro Tezuka, Toshifumi Takahashi, Hirohisa Kurachi
Publikováno v:
Journal of Endocrinology; Dec2004, Vol. 183 Issue 3, p605-615, 11p