Zobrazeno 1 - 9
of 9
pro vyhledávání: '"Akiko Kurimoto"'
Autor:
Masashi Numata, Noriyasu Haginoya, Machiko Shiroishi, Tsuyoshi Hirata, Aiko Sato-Otsubo, Kenji Yoshikawa, Yoshimi Takata, Reina Nagase, Yoshinori Kashimoto, Makoto Suzuki, Nina Schulte, Gernot Polier, Akiko Kurimoto, Yumiko Tomoe, Akiko Toyota, Tomoko Yoneyama, Emi Imai, Kenji Watanabe, Tomoaki Hamada, Ryutaro Kanada, Jun Watanabe, Yoshiko Kagoshima, Eri Tokumaru, Kenji Murata, Takayuki Baba, Taeko Shinozaki, Masami Ohtsuka, Koichi Goto, Tsuyoshi Karibe, Takao Deguchi, Yoshihiro Gocho, Masanori Yoshida, Daisuke Tomizawa, Motohiro Kato, Shinji Tsutsumi, Mayumi Kitagawa, Yuki Abe
Publikováno v:
Cancer Cell International, Vol 23, Iss 1, Pp 1-16 (2023)
Abstract Background Mixed lineage leukemia 1-rearranged (MLL1-r) acute leukemia patients respond poorly to currently available treatments and there is a need to develop more effective therapies directly disrupting the Menin‒MLL1 complex. Small-mole
Externí odkaz:
https://doaj.org/article/f86d0f97c6f6435c8a15c5b3055bcdf2
Autor:
Naoki Goshima, Lumi Negishi, Kei Iwasaki, Yasuko Takeda, Tomoatsu Hayashi, Tetsu Akiyama, Yuki Kamoshida, Akiko Kurimoto, Kenzui Taniue, Yoshifumi Kawamura
Publikováno v:
Oncogene. 39:1018-1030
The epigenetic factor UHRF1 regulates transcription by modulating DNA methylation and histone modification, and plays critical roles in proliferation, development, and tumorigenesis. Here, we show that Wnt/c-Myc signaling upregulates UHRF1, which in
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::34052a40ba624d8bc258b30baaa7a27b
https://doi.org/10.1038/s41388-019-1032-y
https://doi.org/10.1038/s41388-019-1032-y
Autor:
Masakazu Tamura, Makoto Koizumi, Hiroaki Maeda, Akiko Kurimoto, Yasuhide Hirota, Wataru Obuchi, Makiko Nakayama, Hiroshi Tsuchida
Publikováno v:
Nucleosides, Nucleotides & Nucleic Acids. 39:292-309
Double-stranded RNAs consisting of 21-nucleotide passenger and guide strands, known as small interfering RNAs (siRNAs), can be used for the identification of gene functions and the regulation of genes involved in disease for therapeutics. The difficu
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::2a3ba3a683db4982958f3c2c150af12d
https://doi.org/10.1080/15257770.2019.1663384
https://doi.org/10.1080/15257770.2019.1663384
Autor:
Makoto, Koizumi, Yasuhide, Hirota, Makiko, Nakayama, Masakazu, Tamura, Wataru, Obuchi, Akiko, Kurimoto, Hiroshi, Tsuchida, Hiroaki, Maeda
Publikováno v:
Nucleosides, nucleotidesnucleic acids. 39(1-3)
Double-stranded RNAs consisting of 21-nucleotide passenger and guide strands, known as small interfering RNAs (siRNAs), can be used for the identification of gene functions and the regulation of genes involved in disease for therapeutics. The difficu
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::1c4707b0acac819ce12afbd4b7ab8f77
https://pubmed.ncbi.nlm.nih.gov/31509065
https://pubmed.ncbi.nlm.nih.gov/31509065
Autor:
Kenzui Taniue, Takeshi Nagashima, Tetsu Akiyama, Mariko Okada-Hatakeyama, Yuki Katou, Katsuhiko Shirahige, Akiko Kurimoto, Yasuko Takeda
Publikováno v:
Proceedings of the National Academy of Sciences. 113:12739-12744
Wnt/β-catenin signaling plays a key role in the tumorigenicity of colon cancer. Furthermore, it has been reported that lncRNAs are dysregulated in several steps of cancer development. Here we show that β-catenin directly activates the transcription
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::cf0dd151c7c584b7902d7e92feb7ac6f
https://doi.org/10.1073/pnas.1605938113
https://doi.org/10.1073/pnas.1605938113
Autor:
Yukie Suzuki, Kento Tanaka, Yuji Kasuya, Koji Morita, Akiko Kurimoto, Hiroko Yoshida, Kimihisa Ichikawa, Takako Niwa
Publikováno v:
Molecular pharmaceutics. 15(9)
We have developed a technology for efficiently enhancing the anticancer apoptosis-inducing activity of agonistic antibodies against the tumor necrosis factor receptor (TNFR) superfamily by the formation of immunoliposomes. To induce apoptosis in canc
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::af37d996aa657d5f0686d9fc6c798395
https://pubmed.ncbi.nlm.nih.gov/29648839
https://pubmed.ncbi.nlm.nih.gov/29648839
Autor:
Tetsu Akiyama, Yasuko Takeda, Kenzui Taniue, Akiko Kurimoto, Hironobu Sugimasa, Yoshihiro Kawasaki
Publikováno v:
Biochemical and Biophysical Research Communications. 459:29-35
Heterogeneous nuclear ribonucleoprotein K (hnRNP K) is a multi-functional protein involved in transcription, mRNA splicing, mRNA stabilization and translation. Although hnRNP K has been suggested to play a role in the development of many cancers, its
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b629f5dba55cf32876aa0f50887d07f9
https://doi.org/10.1016/j.bbrc.2015.02.043
https://doi.org/10.1016/j.bbrc.2015.02.043
Autor:
Kenzui Taniue, Akiko Kurimoto, Hironobu Sugimasa, Emiko Nasu, Yasuko Takeda, Kei Iwasaki, Takeshi Nagashima, Mariko Okada-Hatakeyama, Masaaki Oyama, Hiroko Kozuka-Hata, Masaya Hiyoshi, Joji Kitayama, Lumi Negishi, Yoshihiro Kawasaki, Tetsu Akiyama
Publikováno v:
Proceedings of the National Academy of Sciences of the United States of America; 2/2/2016, Vol. 113 Issue 5, p1273-1278, 6p
Autor:
Hironobu Sugimasa, Kenzui Taniue, Akiko Kurimoto, Mariko Okada-Hatakeyama, Emiko Nasu, Tetsu Akiyama, Takeshi Nagashima
Publikováno v:
Cancer Research. 73:1831-1831
In recent years, the advent of high-throughput sequencing technologies has revealed that in addition to protein-coding genes, there are an even larger number of RNA transcripts that do not encode proteins and are instead defined as noncoding RNAs (nc
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::08702c76d612b2c418cff4bd707273a6
https://doi.org/10.1158/1538-7445.am2013-1831
https://doi.org/10.1158/1538-7445.am2013-1831