Zobrazeno 1 - 10
of 37
pro vyhledávání: '"Akiko Kanamori"'
Autor:
Akiko Kanamori, Nana Egawa, Suyako Yamasaki, Takehito Ikeda, Marcia Juciele da Rocha, Cristiani Folharini Bortolatto, Lucielli Savegnago, César Augusto Brüning, Michio Iwaoka
Publikováno v:
Pharmaceuticals, Vol 17, Iss 8, p 1049 (2024)
The damage caused by oxidative and glycative stress to cells accumulates on a daily basis and accelerates aging. Glutathione (GSH), a major antioxidant molecule in living organisms, plays a crucial role in detoxifying the stress-causing substances in
Externí odkaz:
https://doaj.org/article/f4987e375dd842358dfaff3eaaf0a9ac
Autor:
Kenta Arai, Akiko Kanamori, Ikumi Nakajima, Manami Saito, Michio Iwaoka, Moeka Sasaki, Yuumi Sato
Publikováno v:
Bioorganic & Medicinal Chemistry. 29:115866
Amphiphilic derivatives of (±)-trans-1,2-diselenane-4,5-diol (DSTox) decorated with long alkyl chains or aromatic substituents via ester linkages were applied as glutathione peroxidase (GPx)-like catalysts. The reduction of H2O2 with the diselenide
Autor:
Masayuki Izumi, Yukishige Ito, Akiko Kanamori, Simone Dedola, Yutaka Makimura, Yoichi Takeda, Akira Seko, Yasuhiro Kajihara
Publikováno v:
Carbohydrate Research. 434:94-98
We previously reported a unique assay system for UDP-glucose glycoprotein glucosyltransferase (UGGT) toward glycoprotein folding intermediates during the folding process. The assay involved the in vitro folding of both high-mannose type oligosacchary
Autor:
Akira Seko, Akiko Kanamori, Masayuki Izumi, Simone Dedola, Yutaka Makimura, Masafumi Sakono, Yukishige Ito, Yasuhiro Kajihara
Publikováno v:
Angewandte Chemie. 126:2927-2931
UDP-glucose:glycoprotein glucosyltransferase (UGGT) plays a key role in recognizing folded and misfolded glycoproteins in the glycoprotein quality control system of the endoplasmic reticulum. UGGT detects misfolded glycoproteins and re-glucosylates t
Autor:
Akiko Kanamori, Chizu Nonomura, Mitsuru Nakamura, Yusuke Furukawa, Jiro Kikuchi, Reiji Kannagi, Kanae Mitsunaga, Hidenobu Ando, Kazuo Muroi, Nobutaka Kiyokawa, Junichiro Fujimoto, Hidenori Ozaki
Publikováno v:
Cancer Research. 68:790-799
B-cell precursor acute lymphoblastic leukemia (BCP-ALL/B-precursor ALL) is characterized by a high rate of tissue infiltration. The mechanism of BCP-ALL cell extravasation is not fully understood. In the present study, we have investigated the major
Publikováno v:
Journal of Carbohydrate Chemistry. 23:201-215
Synthesis and antigenic property of a novel 6‐O‐sulfated sLex neo‐glycolipid containing lactamized neuraminic acid are described. Coupling of methyl (methyl 4,7,8,9‐tetra‐O‐acetyl‐3,5‐dideoxy‐5‐trifluoroacetamido‐D‐glycero‐
Autor:
Akiko Kanamori, Reiji Kannagi, Shigeyuki Yokoyama, Hiroshi Hirota, Toshiyuki Hamada, Nobumasa Otsubo, Masanori Yamaguchi, Hideharu Ishida, Makoto Kiso
Publikováno v:
Tetrahedron Letters. 44:1167-1170
The structure of cyclic sialyl 6-sulfo Lewis x, a new biologically dormant form of L-selectin ligand, was determined unambiguously by the accurate NMR analysis to have the lactamized 5,2 B conformation of its sialic acid. For the NMR structure elucid
Autor:
Akiko Kanamori, Naoya Kojima, Michael C. Berndt, Kenji Uchimura, Takuya Tamatani, Geoffrey S. Kansas, Reiji Kannagi, Takashi Muramatsu
Publikováno v:
Journal of Biological Chemistry. 277:32578-32586
l- and P-selectin are known to require sulfation in their ligand molecules. We investigated the significance of carbohydrate 6-sulfation and tyrosine sulfation in selectin-mediated cell adhesion. COS-7 cells were genetically engineered to express P-s
Autor:
Akiko Kanamori, Nobumasa Otsubo, Shigeyuki Yokoyama, Toshiyuki Hamada, Makoto Kiso, Hideharu Ishida, Hiroshi Hirota, Reiji Kannagi
Publikováno v:
Magnetic Resonance in Chemistry. 40:517-523
Detailed analysis of the 1H and 13C NMR spectra of two novel ganglioside GM4 analogues de-N-acetyl sialyl GM4 (1) and cyclic sialyl GM4 (2), which contain de-N-acetyl and lactamized sialic acid, respectively, instead of the usual N-acetylneuraminic a
Publikováno v:
Cytogenetic and Genome Research. 89:204-208
Rat acetyl-CoA transporter gene (Acatn) encodes a hydrophobic multi-transmembrane protein involved in the O-acetylation of gangliosides. O-acetylated gangliosides have been found to play important roles in the embryonic development of the nervous sys