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pro vyhledávání: '"Akiko Ihoriya"'
Publikováno v:
Synlett. 2010:2330-2334
Asymmetric Darzens-type epoxide formation of aryl aldehydes with chiral para-substituted benzylammonium ylides, prepared from brucine and corresponding benzylic chlorides and treated in situ under basic condition, was carried out to afford chiral 2,3
Autor:
Akiko Ihoriya, Takashi Saika, Toshiaki Sendou, Hidenori Sagara, Yutaka Gomita, Chihiro Tamaki, Fusako Takayama, Hiromu Kawasaki, Hiromi Kumon, Youichi Kawasaki, Hideki Nawa, Toyohiko Watanabe, Hisashi Matsunaga
Publikováno v:
Iryo Yakugaku (Japanese Journal of Pharmaceutical Health Care and Sciences). 34:962-971
In cancer chemotherapy,adverse effects are inevitable and occasionally fatal.Also,the use of appropriate measures against them can greatly influence the QOL of cancer patients so such measures should be taken rapidly.To do this,an extensive knowledge
Publikováno v:
ChemInform. 42
Electron-poor benzylammonium chlorides, generated in situ from benzyl chlorides and brucine, undergo a highly trans-selective asymmetric Darzens-type epoxide synthesis to yield (S,S)-products.