Zobrazeno 1 - 5
of 5
pro vyhledávání: '"Akiko Honsho"'
Publikováno v:
Journal of Biological Chemistry. 274:25136-25143
5-Formyluracil (fU) is a major thymine lesion produced by reactive oxygen radicals and photosensitized oxidation. We have previously shown that fU is a potentially mutagenic lesion due to its elevated frequency to mispair with guanine. Therefore, fU
Autor:
Akiko Honsho, Hiroaki Terato, Keisuke Makino, Toshinori Suzuki, Yoshihiko Ohyama, Masaki Yamada, Aya Masaoka, Hiroshi Ide
Publikováno v:
Nucleic acids symposium series. (44)
Xanthine (Xan) and oxanine (Oxa) are the major deamination products of guanine formed by the treatment with nitrogen oxides (e.g., NO and HNO2). In this study, 2'-deoxyribonucleoside 5'-triphosphates of Xan and Oxa were prepared by the NaNO2 treatmen
Autor:
Toshinori Suzuki, Akiko Honsho, Yoshihiko Ohyama, Aya Masaoka, Hiroaki Terato, Hiroshi Ide, Masaki Yamada, Kenjiro Asagoshi, Keisuke Makino, Kazuo Yamamoto
Publikováno v:
Nucleic acids research. 30(22)
Nitrosation of guanine in DNA by nitrogen oxides such as nitric oxide (NO) and nitrous acid leads to formation of xanthine (Xan) and oxanine (Oxa), potentially cytotoxic and mutagenic lesions. In the present study, we have examined the repair capacit
Autor:
Ke-Qin Xin, Kenji Okuda, Kenji Hamajima, Ichiro Aoki, Atsushi Ihata, Setsuko Watabe, Li-Juan Liu, Britta Wahren, Akiko Honsho
Publikováno v:
Vaccine. 19(31)
We studied the use of a DNA vaccine expressing the matrix (M) gene of the influenza virus A/PR/8/34. Mice were immunized by painting the DNA vaccine three times on the skin after removal of its keratinocytic layers. Immunization by this method produc
Autor:
Kenji Hamajima, Akiko Honsho, Syunsuke Yanoma, Jun Yang, Jun Fukushima, Kenji Okuda, Masatoshi Nakazawa, Ke-Qin Xin
Publikováno v:
Viral immunology. 13(1)