Výsledky vyhledávání - "Akiko Hamaguchi"

Role of Anti‐Fractalkine Antibody in Suppression of Joint Destruction by Inhibiting Migration of Osteoclast Precursors to the Synovium in Experimental Arthritis

Autor: Miyuki Nishimura, Masayoshi Ohkuro, Tsutomu Kamisako, Akiko Hamaguchi, Kana Hoshino-Negishi, Fumihiro Sugiyama, Minoru Kumai, Jungo Kakuta, Toshio Imai, Nobuyuki Yasuda, Wataru Ikeda, Yoko Ida, Tomoya Nakatani, Naoto Ishii, Yoshikazu Kuboi

Publikováno v: Arthritis & Rheumatology. 71:222-231

Objective To elucidate the role of the fractalkine (FKN)/CX3 CR1 pathway in joint destruction in rheumatoid arthritis. Methods We examined the effect of treatment with anti-mouse FKN (anti-mFKN) monoclonal antibody (mAb) on joint destruction and the

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::212b031dcc1cf1e787320b2995e8f1a3
https://doi.org/10.1002/art.40688

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Blockade of the fractalkine–CX3CR1 axis ameliorates experimental colitis by dislodging venous crawling monocytes

Autor: Yoshikazu Kuboi, Miyuki Nishimura, Wataru Ikeda, Tomoya Nakatani, Yukie Seki, Yui Yamaura, Kana Ogawa, Akiko Hamaguchi, Kenzo Muramoto, Keiko Mizuno, Hideaki Ogasawara, Toshihiko Yamauchi, Nobuyuki Yasuda, Hiroshi Onodera, Toshio Imai

Publikováno v: International Immunology. 31:287-302

Chemokine systems modulate inflammatory and immune responses in inflammatory bowel disease (IBD). The colons of IBD patients show increased levels of fractalkine (FKN) and high numbers of FKN receptor-positive (CX3CR1+) cells; however, the FKN–CX3C

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::bae124c80c7d448eacced4ed63f0f52e
https://doi.org/10.1093/intimm/dxz006

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Differences in neurogenic potential in floor plate cells along an anteroposterior location: midbrain dopaminergic neurons originate from mesencephalic floor plate cells

Autor: Yuichi Ono, Jun Takahashi, Yoko Inoue, Yoshimasa Sakamoto, Akiko Hamaguchi, Hideki Hayashi, Miyuki Nishimura, Tomoya Nakatani, Eri Mizuhara, Toshio Imai, Yasuko Minaki, Minoru Kumai

Publikováno v: Development. 134:3213-3225

Directed differentiation and purification of mesencephalic dopaminergic(mesDA) neurons from stem cells are crucial issues for realizing safe and efficient cell transplantation therapies for Parkinson's disease. Although recent studies have identified

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::77b47cb82a17c9df0ba0219eb9ded725
https://doi.org/10.1242/dev.02879

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Interaction of cancer cells with platelets mediated by Necl-5/poliovirus receptor enhances cancer cell metastasis to the lungs

Autor: Masato Okada, Wataru Ikeda, Koji Morimoto, K Satoh-Yamaguchi, Yoshimi Takai, T Imai, Akiko Hamaguchi, Y Inoue, M Takeuchi

Publikováno v: Oncogene. 27:264-273

Necl-5 is an immunoglobulin (Ig)-like molecule that was originally identified as a poliovirus receptor and is often upregulated in cancer cells. We recently found that it colocalizes with integrin alpha(v)beta(3) at the leading edges of moving cells

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::6aa307eee9414360da6d879382af09ed
https://doi.org/10.1038/sj.onc.1210645

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Defective Chemokine-Directed Lymphocyte Migration and Development in the Absence of Rho Guanosine Diphosphate-Dissociation Inhibitors α and β

Autor: Hiroyoshi Ishizaki, Miyuki Nishimura, Atsushi Togawa, Miki Tanaka-Okamoto, Akiko Hamaguchi, Toshio Imai, Yoshimi Takai, Jun Miyoshi, Keiko Hori

Publikováno v: The Journal of Immunology. 177:8512-8521

Rho family small GTP-binding proteins, including Rho, Rac, and Cdc42, are key determinants of cell movement and actin-dependent cytoskeletal morphogenesis. Rho GDP-dissociation inhibitor (GDI) α and Rho GDIβ (or D4/Ly-GDI), closely related regulato

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d3859c5e50c8b60dc82ce6b8bccc2f0e
https://doi.org/10.4049/jimmunol.177.12.8512

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Tage4/Nectin-like Molecule-5 Heterophilically trans-Interacts with Cell Adhesion Molecule Nectin-3 and Enhances Cell Migration

Autor: Akiko Hamaguchi, Koji Morimoto, Shigeki Kakunaga, Tatsushi Shingai, Kyoji Takekuni, Toshio Imai, Keiko Satoh, Yoko Inoue, Wataru Ikeda, Shinsuke Itoh, Yoshimi Takai, Masakazu Takeuchi

Publikováno v: Journal of Biological Chemistry. 278:28167-28172

Malignant transformation of cells causes disruption of cell-cell adhesion, enhancement of cell motility, and invasion into surrounding tissues. Nectins have both homophilic and heterophilic cell-cell adhesion activities and organize adherens junction

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::36bd22eb4bc8f837482db4771607cfb7
https://doi.org/10.1074/jbc.m303586200

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Sa1101 Advanced In Vivo Live Imaging of Vascular Network of Colon Submucosa in IBD Models Using Two-Photon Laser Microscopy

Autor: Kenzo Muramoto, Yoshikazu Kuboi, Yoshihisa Arita, Toshio Imai, Wataru Ikeda, Akiko Hamaguchi

Publikováno v: Gastroenterology. 148:S-224

G A A b st ra ct s and assessed CTT after the swallowing 24, 48 and 72 hours in constipation patients as well as 12 and 48 hours in healthy controls. Pearson correlation coefficient was assessed the association between MRI gadolinium test and ROM to

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::816f73a2a8e2a88b8b58502cd9859c65
https://doi.org/10.1016/s0016-5085(15)30741-1

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A survey of the incidence of single-visit endodontics

Autor: Koko Kojima, Kyoko Inamoto, Akiko Hamaguchi, Kazuhiko Nakata, Kumiko Nagamatsu, Hiroshi Nakamura

Publikováno v: Journal of endodontics. 28(5)

This survey was conducted to obtain answers to some basic questions regarding the timing of root canal obturation. A questionnaire was sent via e-mail to 738 randomly chosen United States endodontists listed in the 1998 to 1999 membership roster of t

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::5d147aee6718f1a3cba316c87c215479
https://pubmed.ncbi.nlm.nih.gov/12026922

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