Výsledky vyhledávání - "Akiko H. Hashimoto"

Data from Enhanced Spontaneous and Benzo(a)pyrene-Induced Mutations in the Lung of Nrf2-Deficient gpt Delta Mice

Autor: Masayuki Yamamoto, Takehiko Nohmi, Ken Itoh, Ken-ichi Masumura, Hirohisa Takano, Kyoko Hiyoshi, Michi Matsumoto, Kimiko Amanuma, Akiko H. Hashimoto, Yasunobu Aoki

The lung is an organ that is sensitive to mutations induced by chemicals in ambient air, and transgenic mice harboring guanine phosphoribosyltransferase (gpt) gene as a target gene are a well-established model system for assessing genotoxicity in viv

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a001179e23d305f7ad2aa254823b96f2
https://doi.org/10.1158/0008-5472.c.6495182.v1

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Alterations in the mutagenicity and mutation spectrum induced by benzo[a]pyrene instilled in the lungs of gpt delta mice of various ages

Autor: Yoshiki Sugawara, Akiko H. Hashimoto, Takehiko Nohmi, Kyoko Hiyoshi-Arai, Sataro Goto, Yasunobu Aoki, Kenichi Masumura

Publikováno v: Genes and Environment

Introduction To examine whether the mutagenic potential of lung exposure to air-borne environmental mutagens is age dependent, we administered 1 mg of benzo[a]pyrene intratracheally to 11- and 24-month old (middle-aged and old, respectively) gpt delt

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::56d2531f56fa26cad23f808ee3d6c5be
https://doi.org/10.1186/s41021-015-0004-x

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In vivo mutagenesis induced by benzo[a]pyrene instilled into the lung ofgpt delta transgenic mice

Autor: Kimiko Amanuma, Yasunobu Aoki, Hirohisa Takano, Kyoko Hiyoshi, Akiko H. Hashimoto, Kenichi Masumura, Takehiko Nohmi

Publikováno v: Environmental and Molecular Mutagenesis. 45:365-373

Benzo[a]pyrene (B[a]P) is a ubiquitous airborne pollutant whose mutagenicity has been evaluated previously by oral and intraperitoneal administration to experimental animals. In this study, mutagenesis in the lungs, the target organ of air pollutants

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::847aee5e9e9d671520be291881f50b06
https://doi.org/10.1002/em.20098

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Quantitative Detection of Trichloroethylene-Degrading Mycobacterium sp. TA27 with a Real-time PCR Product Detection System

Autor: Mutsuyasu Nakajima, Osami Yagi, Akiko H. Hashimoto, Kazuhiro Iwasaki

Publikováno v: Microbes and Environments. 16:109-116

We developed a method for enumerating trichloroethylene (TCE) degrading Mycobacterium sp. TA27 by means of PCR. The PCR primers and probe were designed based on the 16S rRNA sequences of Mycobacterium sp. TA27, compared with corresponding regions of

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::0497f5ff8aac373ef0ee35b1938d7936
https://doi.org/10.1264/jsme2.2001.109

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Degradation of trichloroethylene and related compounds by Mycobacterium spp. isolated from soil

Autor: Mutsuyasu Nakajima, Akiko H. Hashimoto, O. Yagi, N. Nakasugi, Kazuhiro Iwasaki

Publikováno v: Clean Products and Processes. 2:167-173

Mycobacterium spp. strains TA5 and TA27 (ethane-utilizing bacteria), which can degrade trichloroethylene (TCE) and 1,1,1-trichloroethane (1,1,1-TCA), were isolated from soil. Both bacteria could cometabolically degrade dichloromethane, chloroform, 1,

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::e0be2c497d108a8859c7930bab21d439
https://doi.org/10.1007/pl00011304

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