Zobrazeno 1 - 7
of 7
pro vyhledávání: '"Akiko Futakuchi-Tsuchida"'
Autor:
Hans Reinecke, Deok Ho Kim, Lil Pabon, Joy Xu, Kai Chun Yang, Akiko Futakuchi-Tsuchida, Michael Regnier, Maria V. Razumova, Peter Hofsteen, Charles E. Murry, J. Carter Ralphe, Cody Schopf, Alex Jiao, Astrid Breitbart, Robert J. Boucek, Willem J. de Lange
Publikováno v:
JACC: Basic to Translational Science
JACC: Basic to Translational Science, Vol 3, Iss 6, Pp 728-740 (2018)
JACC: Basic to Translational Science, Vol 3, Iss 6, Pp 728-740 (2018)
Visual Abstract
Highlights • Many cardiomyopathy families have genetic variants whose significance is unknown. We studied a novel (E848G) mutation in MYH7, a sarcomeric protein. • Patient-specific induced pluripotent stem cell–derived card
Highlights • Many cardiomyopathy families have genetic variants whose significance is unknown. We studied a novel (E848G) mutation in MYH7, a sarcomeric protein. • Patient-specific induced pluripotent stem cell–derived card
Autor:
Hans Reinecke, Akiko Futakuchi-Tsuchida, Charles E. Murry, Xiulan Yang, Bjorn C. Knollmann, Alessandro Bertero, Silvia Marchianò, Kevin C. Cain, Dale Whittington, Faith A. Kalucki, Steven Kattman, Sarah K. Dupras, R. S. Thies, Lauren E. Neidig, Danny El-Nachef, Hiroshi Tsuchida, W. R. MacLellan, D. S. Nakamura, Melissa R. Robinson, Kenta Nakamura, G. J. Weber, Lil Pabon, A. Jayabalu
BackgroundEngraftment arrhythmias (EAs) are observed in large animal studies of intramyocardial transplantation of human pluripotent stem cell-derived cardiomyocytes (hPSC-CMs) for myocardial infarction. Although transient, the risk posed by EA prese
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::5fb14e6b2cda2c3ed4e2853292a7f301
https://doi.org/10.1101/2021.02.15.431108
https://doi.org/10.1101/2021.02.15.431108
Autor:
Alessandro Bertero, Rong Tian, Kevin C. Cain, R. Scott Thies, Anu Jayabalu, Melissa R. Robinson, W. Robb MacLellan, Danny El-Nachef, Dale Whittington, Daisy S. Nakamura, Faith A. Kalucki, Hiroshi Tsuchida, Lauren E. Neidig, Gerhard J. Weber, Charles E. Murry, Silvia Marchianò, Lil Pabon, Akiko Futakuchi-Tsuchida, Bjorn C. Knollmann, Xiulan Yang, Steven Kattman, Hans Reinecke, Sarah K. Dupras, Kenta Nakamura
Publikováno v:
Stem Cell Reports
Summary Heart failure remains a significant cause of morbidity and mortality following myocardial infarction. Cardiac remuscularization with transplantation of human pluripotent stem cell-derived cardiomyocytes is a promising preclinical therapy to r
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e1189e00de9d9819aacf1d2936c5a883
http://hdl.handle.net/2318/1804571
http://hdl.handle.net/2318/1804571
Autor:
Lil Pabon, Stephanie A. Tuck, Audrey Baldessari, Dale W. Hailey, Keith W. Vogel, Zachary L. Steinberg, Faith A. Kalucki, Stephen P. Seslar, Billy Chen, Hiroshi Tsuchida, Jason Ogle, W. Robb MacLellan, Akiko Futakuchi-Tsuchida, Milly S. Lyu, R. Scott Thies, Charles E. Murry, Yen Wen Liu, Larry A. Couture, Hans Reinecke, Xiulan Yang, Sarah K. Dupras, Anna V. Naumova, Benjamin H. Fryer, Creighton W. Don, James Chun-I Lee, Clifford A. Astley, James A. Fugate
Publikováno v:
Nature Biotechnology. 36:597-605
Pluripotent stem cell-derived cardiomyocyte grafts can remuscularize substantial amounts of infarcted myocardium and beat in synchrony with the heart, but in some settings cause ventricular arrhythmias. It is unknown whether human cardiomyocytes can
Autor:
Billy Chen, James Chun-I Lee, Creighton W. Don, Stephanie A. Tuck, Lil Pabon, Hans Reinecke, Audrey Baldessari, James A. Fugate, Keith W. Vogel, Zachary L. Steinberg, Faith A. Kalucki, Clifford A. Astley, Dale W. Hailey, Xiulan Yang, Jason Ogle, Stephen P. Seslar, Sarah K. Dupras, Akiko Futakuchi-Tsuchida, Milly S. Lyu, Anna V. Naumova, Benjamin H. Fryer, Larry A. Couture, R. Scott Thies, Charles E. Murry, Hiroshi Tsuchida, W. Robb MacLellan, Yen-Wen Liu
Publikováno v:
Nature Biotechnology. 36:899-899
Nat. Biotechnol. 36, 597–605 (2018); published online 2 July 2018; corrected after print 18 July 2018 In the version of this article initially published, NIH grant P51 OD010425 was omitted. The error has been corrected in the HTML and PDF versions
Publikováno v:
Future Cardiology. 9:151-154
Autor:
Makoto Takahashi, Osamu Ando, Hironori Matsunaga, Makoto Tsuji, Akiko Futakuchi-Tsuchida, Tomio Ishikawa
Publikováno v:
Biochemical and biophysical research communications. 423(3)
D-2-hydroxyglutaric aciduria (D-2HGA) is a hereditary metabolic disorder characterized by the elevated levels of D-2-hydroxyglutaric acid (D-2HG) in urine, plasma and cerebrospinal fluid. About half of the patients have autosomal recessive mutations