Zobrazeno 1 - 10
of 157
pro vyhledávání: '"Akiko Eguchi"'
Autor:
Nils Becker, Niklas Franz, Akiko Eguchi, Alessa Wagner, Ramona Sturm, Helen Rinderknecht, Yoshinao Kobayashi, Motoh Iwasa, Birte Weber, Ingo Marzi, Borna Relja
Publikováno v:
Frontiers in Immunology, Vol 15 (2024)
BackgroundExtracellular particles (EPs), particularly extracellular vesicles, play a crucial role in regulating various pathological mechanisms, including immune dysregulations post-trauma. Their distinctive expression of cell-specific markers and re
Externí odkaz:
https://doaj.org/article/a0bd187bbceb4c359f51fdb960ab14a5
Autor:
Akiko Eguchi, Motoh Iwasa, Ryosuke Sugimoto, Mina Tempaku, Kyoko Yoshikawa, Naohiko Yoshizawa, Davide Povero, Kazushi Sugimoto, Hiroshi Hasegawa, Yoshiyuki Takei, Hayato Nakagawa
Publikováno v:
Hepatology Communications, Vol 6, Iss 12, Pp 3515-3527 (2022)
Abstract Complement complex 1 subunit q (C1q) has multiple functions, including cell migration, in addition to its traditional complement‐activating effect. Research shows C1q is a ligand for frizzled receptors (FZDs). FZD‐induced yes‐associate
Externí odkaz:
https://doaj.org/article/f777e468e1c34e10996bb4629e88fc8c
Autor:
Akiko Eguchi, Motoh Iwasa, Minori Yamada, Yasuyuki Tamai, Ryuta Shigefuku, Hiroshi Hasegawa, Yoshifumi Hirokawa, Akinobu Hayashi, Koji Okuno, Yuki Matsushita, Takuma Nakatsuka, Kenichiro Enooku, Koji Sakaguchi, Yoshinao Kobayashi, Tetsuji Yamaguchi, Masatoshi Watanabe, Yoshiyuki Takei, Hayato Nakagawa
Publikováno v:
Hepatology Communications, Vol 6, Iss 8, Pp 1987-1999 (2022)
Abstract Caspase‐generated fragmented cytokeratin 18 (fCK18) is recognized as a useful noninvasive biomarker in the diagnosis of nonalcoholic fatty liver disease (NAFLD), particularly nonalcoholic steatohepatitis (NASH). However, fCK18 measurement
Externí odkaz:
https://doaj.org/article/f9f1c1e15e4f47858312cd5199aaa819
Autor:
Aleksandra Leszczynska, Christian Stoess, Hana Sung, Davide Povero, Akiko Eguchi, Ariel Feldstein
Publikováno v:
Biomedicines, Vol 11, Iss 10, p 2808 (2023)
Chronic liver diseases can lead to fibrotic changes that may progress to the development of cirrhosis, which poses a significant risk for morbidity and increased mortality rates. Metabolic dysfunction-associated steatotic liver disease (MASLD), alcoh
Externí odkaz:
https://doaj.org/article/4d5343623b1a46c9b5d3d2200d1e81a6
Autor:
Davide Povero, Masahiko Tameda, Akiko Eguchi, Wenhua Ren, Jihoon Kim, Robert Myers, Zachary D. Goodman, Stephen A. Harrison, Arun J. Sanyal, Jaime Bosch, Lucila Ohno-Machado, Ariel E. Feldstein
Publikováno v:
Scientific Reports, Vol 12, Iss 1, Pp 1-11 (2022)
Abstract Primary sclerosing cholangitis (PSC) is an idiopathic and heterogenous cholestatic liver disease characterized by chronic inflammation and fibrosis of the biliary tree. Currently, no effective therapies are available for this condition, whos
Externí odkaz:
https://doaj.org/article/f7dd9db4292b4f9fb959aa9ca0e2edfd
Autor:
Ryosuke Sugimoto, Motoh Iwasa, Akiko Eguchi, Yasuyuki Tamai, Ryuta Shigefuku, Naoto Fujiwara, Hideaki Tanaka, Yoshinao Kobayashi, Jiro Ikoma, Masahiko Kaito, Hayato Nakagawa
Publikováno v:
Frontiers in Medicine, Vol 10 (2023)
Background/AimsPemafibrate is a selective peroxisome proliferator-activated receptor α modulator that improves serum alanine aminotransferase (ALT) in dyslipidemia patients. Pemafibrate was reported to reduce ALT in non-alcoholic fatty liver disease
Externí odkaz:
https://doaj.org/article/2465595da9d547e7aa5b66227262b005
Publikováno v:
JGH Open, Vol 5, Iss 11, Pp 1250-1256 (2021)
Abstract Liver cirrhosis is the final stage of chronic liver disease (CLD) and is associated with high morbidity and mortality. Various complications such as portal hypertension, ascites retention, hepatic encephalopathy, and hepatorenal syndrome dee
Externí odkaz:
https://doaj.org/article/11754e7c2d96405fa5479faf69d9ced1
Publikováno v:
Scientific Reports, Vol 11, Iss 1, Pp 1-9 (2021)
Abstract Fragmented cytokeratin 18 (fCK18) released from epithelial cells undergoing apoptosis is widely studied in various diseases. However, fCK18 measurement is not utilized in clinical practice due to imprecise disease-state cutoff values. Theref
Externí odkaz:
https://doaj.org/article/7efd161cd1164461a9c4b5bcb61a353a
Autor:
Yasuyuki Tamai, Akiko Eguchi, Ryuta Shigefuku, Hiroshi Kitamura, Mina Tempaku, Ryosuke Sugimoto, Yoshinao Kobayashi, Motoh Iwasa, Yoshiyuki Takei, Hayato Nakagawa
Publikováno v:
eLife, Vol 11 (2022)
Background: Hepatic sarcopenia is one of many complications associated with chronic liver disease (CLD) and has a high mortality rate; however, the liver-muscle axis is not fully understood. Therefore, few effective treatments exist for hepatic sarco
Externí odkaz:
https://doaj.org/article/9d9ad1ffcbca4c8bab44dc5bb9f59cc8
Autor:
Yasuyuki Tamai, Motoh Iwasa, Akiko Eguchi, Ryuta Shigefuku, Yoshihiro Kamada, Eiji Miyoshi, Yoshiyuki Takei
Publikováno v:
JGH Open, Vol 5, Iss 7, Pp 827-830 (2021)
Externí odkaz:
https://doaj.org/article/928ba1ddd80546acac04170d702200c1