Zobrazeno 1 - 10 of 78 pro vyhledávání: '"Akiko Asano"'
1
Akademický článek
Puckering effects of 4-hydroxy-l-proline isomers on the conformation of ornithine-free Gramicidin S
Autor: Akiko Asano, Kanako Nakayama, Sakura Okada, Takuma Kato, Mitsunobu Doi
Publikováno v: Acta Crystallographica Section E: Crystallographic Communications, Vol 80, Iss 9, Pp 942-946 (2024)
The cyclic peptide cyclo(Val-Leu-Leu-D-Phe-Pro)2 (peptide 1) was specifically designed for structural chemistry investigations, drawing inspiration from Gramicidin S (GS). Previous studies have shown that Pro residues within 1 adopt a down-puckering
Externí odkaz: https://doaj.org/article/1b8653b7c5694aa6a8c36fe9fb50f242
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2
Akademický článek
Crystal structure of N-{N-[N-(tert-butoxycarbonyl)-l-α-aspartyl]-l-α-aspartyl}-l-α-aspartic acid 14,24,34-trimethyl ester 31-2-oxo-2-phenylethyl ester {Boc-[Asp(OMe)]3-OPac}
Autor: Takuma Kato, Saki Kishimoto, Akiko Asano, Mitsunobu Doi
Publikováno v: Acta Crystallographica Section E: Crystallographic Communications, Vol 75, Iss 5, Pp 585-588 (2019)
In the title homotripeptide {Boc-[Asp(OMe)]3-OPac}, C28H37N3O13, all peptide bonds adopt an s-trans conformation with respect to the N—H and C=O groups. In the crystal, N—H...O hydrogen bonds result in an infinite parallel β-sheet structure runn
Externí odkaz: https://doaj.org/article/88c04977732945c98f5d6f1477b7f188
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3
Akademický článek
Integrated mental health care in a multidisciplinary maternal and child health service in the community: the findings from the Suzaka trial
Autor: Yoshiyuki Tachibana, Noriaki Koizumi, Chikako Akanuma, Hiromi Tarui, Eizaburo Ishii, Tomomi Hoshina, Ayuko Suzuki, Akiko Asano, Shiho Sekino, Hiroto Ito
Publikováno v: BMC Pregnancy and Childbirth, Vol 19, Iss 1, Pp 1-11 (2019)
Abstract Background Perinatal mental health problems such as mood disorders are common. We propose a new multidisciplinary health service intervention program providing continuous support to women and their children from the start of pregnancy till a
Externí odkaz: https://doaj.org/article/8b43937d70e041f5a633749a0b122b7a
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4
Akademický článek
Diagnosis of Tooth Prognosis Using Artificial Intelligence
Autor: Sang J. Lee, Dahee Chung, Akiko Asano, Daisuke Sasaki, Masahiko Maeno, Yoshiki Ishida, Takuya Kobayashi, Yukinori Kuwajima, John D. Da Silva, Shigemi Nagai
Publikováno v: Diagnostics, Vol 12, Iss 6, p 1422 (2022)
The accurate diagnosis of individual tooth prognosis has to be determined comprehensively in consideration of the broader treatment plan. The objective of this study was to establish an effective artificial intelligence (AI)-based module for an accur
Externí odkaz: https://doaj.org/article/dd30f8b5e08d4d3a937d1cf45a2ce5f4
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5
Akademický článek
The desoxazoline asidiacyclamide analogue cyclo(Gly–Thr–D-Val–Thz–Ile–Thr–D-Val–Thz) acetonitrile monosolvate
Autor: Akiko Asano, Mitsunobu Doi
Publikováno v: Acta Crystallographica Section E, Vol 68, Iss 1, Pp o54-o55 (2012)
The title peptide [systematic name: 4-(butan-2-yl)-7,20-bis(1-hydroxyethyl)-10,23-bis(propan-2-yl)-12,25-dithia-3,6,9,16,19,22,27,28-octaazatricyclo[22.2.1.111,14]octacosa-1(26),11(28),13,24(27)-tetraene-2,5,8,15,18,21-hexone acetonitrile monosolvate
Externí odkaz: https://doaj.org/article/9701e882cfda468d92ff2a1c26c0670e
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6
Akademický článek
H–d-Phe–d-Pro–Gly methyl ester hydrochloride monohydrate
Autor: Akiko Asano, Yuko Ichimiya, Mitsunobu Doi
Publikováno v: Acta Crystallographica Section E, Vol 64, Iss 4, Pp o704-o704 (2008)
The conformation of the title tripeptide methyl ester hydrochloride monohydrate, 1-[2-(methoxycarbonylmethylaminocarbonyl)pyrrolidin-1-ylcarbonyl]-2-phenylethanaminium chloride monohydrate, C17H24N3O4+·Cl−·H2O, is extended, but the structure cann
Externí odkaz: https://doaj.org/article/4843091856f8455095658b506eaf5b13
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8
Experimental evidence for CH⋯π interaction-mediated stabilization of the square form in phenylglycine-incorporated ascidiacyclamide
Autor: Akiko Asano, Katsuhiko Minoura, Takeshi Yamada, Mitsunobu Doi
Publikováno v: RSC Advances. 13:2458-2466
The thermodynamic parameters through NMR-based quantitation provided evidence for the CH⋯π interaction in phenyl group-incorporated ascidiacyclamide. Stabilization of the square form by CH⋯π interaction resulted in increased cytotoxicity.
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::10c297d5141639a91189bbd21afa83d7
https://doi.org/10.1039/d2ra07063d
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10
Effects of Substituting Disubstituted Amino Acids into the Amphipathic Cell Penetrating Peptide Pep-1
Autor: Takuma, Kato, Hiroaki, Numa, Mihoko, Nakamachi, Akiko, Asano, Mitsunobu, Doi
Publikováno v: Chemical and Pharmaceutical Bulletin. 70:812-817
Amphipathic cell-penetrating peptides based on the pep-1 sequence were synthesized by replacing the three hydrophilic glutamic acid residues with disubstituted, non-proteinogenic, hydrophobic amino acids. These substitutions facilitated maintenance o
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::7c14b52007ae75e701812b89dd8f15d9
https://doi.org/10.1248/cpb.c22-00472
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