Zobrazeno 1 - 10
of 61
pro vyhledávání: '"Akiko, Takizawa"'
Autor:
Yoneko Hayase, Shigeru Amano, Koichi Hashizume, Takashi Tominaga, Hiroyuki Miyamoto, Yukie Kanno, Yukiko Ueno-Inoue, Takayoshi Inoue, Mayumi Yamada, Shigehiro Ogata, Shabeesh Balan, Ken Hayashi, Yoshiki Miura, Kentaro Tokudome, Yukihiro Ohno, Takuma Nishijo, Toshihiko Momiyama, Yuchio Yanagawa, Akiko Takizawa, Tomoji Mashimo, Tadao Serikawa, Akihiro Sekine, Eiji Nakagawa, Eri Takeshita, Takeo Yoshikawa, Chikako Waga, Ken Inoue, Yu-ichi Goto, Yoichi Nabeshima, Nobuo Ihara, Kazuhiro Yamakawa, Shinichiro Taya, Mikio Hoshino
Publikováno v:
Acta Neuropathologica Communications, Vol 8, Iss 1, Pp 1-17 (2020)
Abstract The Ihara epileptic rat (IER) is a mutant model with limbic-like seizures whose pathology and causative gene remain elusive. In this report, via linkage analysis, we identified Down syndrome cell adhesion molecule-like 1(Dscaml1) as the resp
Externí odkaz:
https://doaj.org/article/83b2c846e60840adb9d55f24ef0bdf26
Autor:
Melinda Dwinell, Akiko Takizawa, Lynn Malloy, Monika Tutaj, Rebecca Schilling, Aron Geurts, Anne Kwitek
Publikováno v:
Physiology. 38
Rats are a major model for studying complex disease mechanisms, behavioral phenotypes, environmental factors, and for drug development and discovery. Inbred rat strains control for genetic background and allow for repeated, reproducible molecular, ce
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::37b3e9636a378d8d3a36a73b48b317f7
https://doi.org/10.1152/physiol.2023.38.s1.5732554
https://doi.org/10.1152/physiol.2023.38.s1.5732554
Autor:
Arthur P. Arnold, Xuqi Chen, Michael N. Grzybowski, Janelle M. Ryan, Dale R. Sengelaub, Tara Mohanroy, V. Andree Furlan, William Grisham, Lynn Malloy, Akiko Takizawa, Carrie B. Wiese, Laurent Vergnes, Helen Skaletsky, David C. Page, Karen Reue, Vincent R. Harley, Melinda R. Dwinell, Aron M. Geurts
Publikováno v:
bioRxiv
BackgroundWe have generated a rat model similar to the Four Core Genotypes mouse model, allowing comparison of XX and XY rats with the same type of gonad. The model detects novel sex chromosome effects (XX vs. XY) that contribute to sex differences i
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::559a36c2812afc8ea3d0f8c3e1815313
https://europepmc.org/articles/PMC9934672/
https://europepmc.org/articles/PMC9934672/
Autor:
Toshihito Fujii, Keisho Hirota, Akihiro Yasoda, Akiko Takizawa, Naomi Morozumi, Ryuichi Nakamura, Takafumi Yotsumoto, Eri Kondo, Yui Yamashita, Yoriko Sakane, Yugo Kanai, Yohei Ueda, Ichiro Yamauchi, Shigeki Yamanaka, Kazumasa Nakao, Koichiro Kuwahara, Toshimasa Jindo, Mayumi Furuya, Tomoji Mashimo, Nobuya Inagaki, Tadao Serikawa, Kazuwa Nakao
Publikováno v:
PLoS ONE, Vol 13, Iss 3, p e0194812 (2018)
We have previously investigated the physiological role of C-type natriuretic peptide (CNP) on endochondral bone growth, mainly with mutant mouse models deficient in CNP, and reported that CNP is indispensable for physiological endochondral bone growt
Externí odkaz:
https://doaj.org/article/f529792eec9d4297a02abdca277c4211
Autor:
Matthew J. Hoffman, Akiko Takizawa, Eric S. Jensen, Rebecca Schilling, Michael Grzybowski, Aron M. Geurts, Melinda R. Dwinell
Publikováno v:
Physiol Genomics
Hypertension (HTN) is a complex disease influenced by heritable genetic elements and environmental interactions. Dietary salt is among the most influential modifiable factors contributing to increased blood pressure (BP). It is well established that
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b42397e8fad38f7a2ca66e2565479270
https://europepmc.org/articles/PMC9208437/
https://europepmc.org/articles/PMC9208437/
Autor:
Melinda Dwinell, Akiko Takizawa, Lynn Lazcares, Monika Tutaj, Rebecca Schilling, Aron Geurts, Anne Kwitek
Publikováno v:
The FASEB Journal. 36
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::ced466c271936c439dccb3549e03504a
https://doi.org/10.1096/fasebj.2022.36.s1.r2020
https://doi.org/10.1096/fasebj.2022.36.s1.r2020
Autor:
Tomoji Mashimo, Akiko Takizawa, Junya Kobayashi, Yayoi Kunihiro, Kazuto Yoshimi, Saeko Ishida, Koji Tanabe, Ami Yanagi, Asato Tachibana, Jun Hirose, Jun-ichiro Yomoda, Shiho Morimoto, Takashi Kuramoto, Birger Voigt, Takeshi Watanabe, Hiroshi Hiai, Chise Tateno, Kenshi Komatsu, Tadao Serikawa
Publikováno v:
Cell Reports, Vol 2, Iss 3, Pp 685-694 (2012)
Severe combined immunodeficiency (SCID) mice, the most widely used animal model of DNA-PKcs (Prkdc) deficiency, have contributed enormously to our understanding of immunodeficiency, lymphocyte development, and DNA-repair mechanisms, and they are idea
Externí odkaz:
https://doaj.org/article/d76e2b1b1e7545bf810b03de707531d5
Autor:
Akihiro Sekine, Mikio Hoshino, Tomoji Mashimo, Ken Hayashi, Shigeru Amano, Mayumi Yamada, Takuma Nishijo, Hiroyuki Miyamoto, Toshihiko Momiyama, Nobuo Ihara, Ken Inoue, Chikako Waga, Shigehiro Ogata, Eri Takeshita, Koichi Hashizume, Yukie Kanno, Yuchio Yanagawa, Takeo Yoshikawa, Tadao Serikawa, Yukihiro Ohno, Yukiko Ueno-Inoue, Eiji Nakagawa, Yo-ichi Nabeshima, Shinichiro Taya, Akiko Takizawa, Shabeesh Balan, Yu-ichi Goto, Takashi Tominaga, Yoneko Hayase, Kazuhiro Yamakawa, Kentaro Tokudome, Takayoshi Inoue, Yoshiki Miura
Publikováno v:
Acta Neuropathologica Communications
Acta Neuropathologica Communications, Vol 8, Iss 1, Pp 1-17 (2020)
Acta Neuropathologica Communications, Vol 8, Iss 1, Pp 1-17 (2020)
The Ihara epileptic rat (IER) is a mutant model with limbic-like seizures whose pathology and causative gene remain elusive. In this report, via linkage analysis, we identified Down syndrome cell adhesion molecule-like 1(Dscaml1) as the responsible g
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::41d905cbde994b58ca5ed5c62b8ad722
https://doi.org/10.1186/s40478-020-01082-6
https://doi.org/10.1186/s40478-020-01082-6
Autor:
Aron M. Geurts, Matthew Hoffman, Eric Jensen, Rebecca Schilling, Michael Grzybowski, Akiko Takizawa, Melinda R. Dwinell
Publikováno v:
Hypertension. 76
Hypertension (HTN) is a complex disease influenced by heritable genetic elements and environmental interactions. Dietary salt is among the most influential modifiable factors contributing to increased blood pressure (BP). It is well established that
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::89435e1d34f5975596b0fd877950e30d
https://doi.org/10.1161/hyp.76.suppl_1.p124
https://doi.org/10.1161/hyp.76.suppl_1.p124
Autor:
Tomoji Mashimo, Akiko Takizawa, Birger Voigt, Kazuto Yoshimi, Hiroshi Hiai, Takashi Kuramoto, Tadao Serikawa
Publikováno v:
PLoS ONE, Vol 5, Iss 1, p e8870 (2010)
BACKGROUND: Although the rat is extensively used as a laboratory model, the inability to utilize germ line-competent rat embryonic stem (ES) cells has been a major drawback for studies that aim to elucidate gene functions. Recently, zinc-finger nucle
Externí odkaz:
https://doaj.org/article/78a5092a4cf84d69bc26d693c9d63147