Zobrazeno 1 - 10
of 27
pro vyhledávání: '"Akiko, Igawa"'
Autor:
Yutaro Hara, Hiroki Mizukami, Keisuke Yamazaki, Takahiro Yamada, Akiko Igawa, Yuki Takeuchi, Takanori Sasaki, Hanae Kushibiki, Kotaro Murakami, Kazuhiro Kudoh, Keinosuke Ishido, Kenichi Hakamada
Publikováno v:
The Journal of Pathology: Clinical Research, Vol 9, Iss 5, Pp 354-366 (2023)
Abstract Diabetes mellitus (DM) is a risk factor for pancreatic ductal adenocarcinoma (PDAC) that promotes the promoter methylation of CDH1. It is still unclear whether DM can exert other epigenetic effects, such as altering microRNA (miR) expression
Externí odkaz:
https://doaj.org/article/49220e3a8e094148a1c67db469d803bb
Autor:
Xuekai Pan, Hiroki Mizukami, Yutaro Hara, Takahiro Yamada, Keisuke Yamazaki, Kazuhiro Kudoh, Yuki Takeuchi, Takanori Sasaki, Hanae Kushibiki, Akiko Igawa, Kenichi Hakamada
Publikováno v:
Journal of Diabetes Investigation, Vol 14, Iss 1, Pp 132-144 (2023)
ABSTRACT Aims/Introduction The mismatch repair (MMR) protein recognizes DNA replication errors and plays an important role in tumorigenesis, including pancreatic ductal adenocarcinoma (PDAC). Although PMS2, a MMR protein, is degraded under oxidative
Externí odkaz:
https://doaj.org/article/6998ae817b84431d853edfa8cde7bac6
Autor:
Yuki Takeuchi, Hiroki Mizukami, Kazuhiro Kudoh, Sho Osonoi, Takanori Sasaki, Hanae Kushibiki, Saori Ogasawara, Yutaro Hara, Akiko Igawa, Xuekai Pan, Takahiro Yamada, Keisuke Yamazaki, Tatsuya Mikami, Makoto Daimon, Soroku Yagihashi, Kenichi Hakamada, Shigeyuki Nakaji
Publikováno v:
Neurobiology of Disease, Vol 173, Iss , Pp 105839- (2022)
Small fibre neuropathy (SFN) is an initial pathology of diabetic polyneuropathy (DPN). Serum lipopolysaccharide binding protein levels are positively correlated with the pain threshold in the foot, suggesting that the abundance of gut Gram-negative b
Externí odkaz:
https://doaj.org/article/804f72b69a584cf08541270d878eeaff
Autor:
Kazuhiro Kudoh, Hiroki Mizukami, Chieko Itabashi, Nobuo Fuke, Sho Osonoi, Kanichiro Wada, Akiko Igawa, Saori Ogasawara, Yasuyuki Ishibashi, Kenichi Hakamada, Soroku Yagihashi, Shigeyuki Nakaji
Publikováno v:
BMJ Open Diabetes Research & Care, Vol 8, Iss 1 (2020)
Introduction Small fiber neuropathy (SFN) is an early manifestation in diabetic polyneuropathy (DPN); however, the mechanisms are not fully understood. In diabetes, SFN is presumed to be common in individuals with overt DPN, enhancing activation of p
Externí odkaz:
https://doaj.org/article/981385343e30429080b52457061bd6a6
Autor:
Chieko Itabashi, Hiroki Mizukami, Sho Osonoi, Kazuhisa Takahashi, Kazuhiro Kudo, Kanichiro Wada, Wataru Inaba, Guo Danyang, Chiaki Uchida, Satoko Umetsu, Akiko Igawa, Saori Ogasawara, Masaki Ryuzaki, Kouji Komeda, Yasuyuki Ishibashi, Soroku Yagihashi, Shigeyuki Nakaji
Publikováno v:
Frontiers in Endocrinology, Vol 11 (2020)
Externí odkaz:
https://doaj.org/article/2e61f43673464d04b2870ed922b2fe98
Autor:
Chieko Itabashi, Hiroki Mizukami, Sho Osonoi, Kazuhisa Takahashi, Kazuhiro Kudo, Kanichiro Wada, Wataru Inaba, Guo Danyang, Chiaki Uchida, Satoko Umetsu, Akiko Igawa, Saori Ogasawara, Masaki Ryuzaki, Kouji Komeda, Yasuyuki Ishibashi, Soroku Yagihashi, Shigeyuki Nakaji
Publikováno v:
Frontiers in Endocrinology, Vol 10 (2019)
Purpose: Small fiber dysfunction is common in subjects with diabetic polyneuropathy (DPN). It is unsettled, however, whether marginal glucose intolerance is implicated in the onset and progression of small fiber dysfunction. Herein, we explored the r
Externí odkaz:
https://doaj.org/article/3b9cc9ea4f7f463a91ecdc16b690b21c
Autor:
Kazunori Kageyama, Noriko Ishigame, Aya Sugiyama, Akiko Igawa, Takashi Nishi, Satoko Morohashi, Hiroshi Kijima, Makoto Daimon
Publikováno v:
Case Reports in Endocrinology, Vol 2017 (2017)
We report a case of a 66-year-old woman who developed hyperparathyroidism due to a large intrathyroid parathyroid adenoma with episodes of acute pancreatitis. She had previously been treated for acute pancreatitis twice. Serum calcium was 12.4 mg/dL,
Externí odkaz:
https://doaj.org/article/e936c42a29964a1096f934c854d36140
Autor:
Xuekai Pan, Hiroki Mizukami, Yutaro Hara, Takahiro Yamada, Keisuke Yamazaki, Kazuhiro Kudoh, Yuki Takeuchi, Takanori Sasaki, Hanae Kushibiki, Akiko Igawa, Kenichi Hakamada
Publikováno v:
Journal of diabetes investigationREFERENCES. 14(1)
The mismatch repair (MMR) protein recognizes DNA replication errors and plays an important role in tumorigenesis, including pancreatic ductal adenocarcinoma (PDAC). Although PMS2, a MMR protein, is degraded under oxidative stress, the effects of diab
Autor:
Akiko Igawa, Hiroki Mizukami, Kazuhiro Kudoh, Yuki Takeuchi, Takanori Sasaki, Xuekai Pan, Kenichi Hakamada
Publikováno v:
Virchows Archiv : an international journal of pathology. 481(4)
Invasive lobular carcinoma (ILC) is characterized by discohesive cells due to irreversible loss of E-cadherin expression and multiple satellites, where individual cell migration is evident without disturbance of the stroma. Neoplastic cells sometimes
Autor:
Nobuo Fuke, Kanichiro Wada, Chieko Itabashi, Yuki Takeuchi, Sho Osonoi, Akiko Igawa, Yasuyuki Ishibashi, Soroku Yagihashi, Saori Ogasawara, Kazuhiro Kudoh, Hiroki Mizukami, Kenichi Hakamada, Shigeyuki Nakaji
Publikováno v:
BMJ Open Diabetes Research & Care
BMJ Open Diabetes Research & Care, Vol 8, Iss 1 (2020)
BMJ Open Diabetes Research & Care, Vol 8, Iss 1 (2020)
IntroductionSmall fiber neuropathy (SFN) is an early manifestation in diabetic polyneuropathy (DPN); however, the mechanisms are not fully understood. In diabetes, SFN is presumed to be common in individuals with overt DPN, enhancing activation of po