Zobrazeno 1 - 10
of 193
pro vyhledávání: '"Akiko, Hashimoto"'
Autor:
Akiko Hashimoto-Tane, Edward P. Bowman, Machie Sakuma, Natsumi Yoneda, Katsuyuki Yugi, Rene de Waal Malefyt, Takashi Saito
Publikováno v:
Frontiers in Immunology, Vol 15 (2024)
Lymphocyte activation gene (Lag)-3 is an inhibitory co-receptor and target of immune checkpoint inhibitor (ICI) therapy for cancer. The dynamic behavior of Lag-3 was analyzed at the immune synapse upon T-cell activation to elucidate the Lag-3 inhibit
Externí odkaz:
https://doaj.org/article/01488bb5ac8c4a6ab38ab7b584d9ff15
Autor:
Alistair T. Pagnamenta, Carme Camps, Edoardo Giacopuzzi, John M. Taylor, Mona Hashim, Eduardo Calpena, Pamela J. Kaisaki, Akiko Hashimoto, Jing Yu, Edward Sanders, Ron Schwessinger, Jim R. Hughes, Gerton Lunter, Helene Dreau, Matteo Ferla, Lukas Lange, Yesim Kesim, Vassilis Ragoussis, Dimitrios V. Vavoulis, Holger Allroggen, Olaf Ansorge, Christian Babbs, Siddharth Banka, Benito Baños-Piñero, David Beeson, Tal Ben-Ami, David L. Bennett, Celeste Bento, Edward Blair, Charlotte Brasch-Andersen, Katherine R. Bull, Holger Cario, Deirdre Cilliers, Valerio Conti, E. Graham Davies, Fatima Dhalla, Beatriz Diez Dacal, Yin Dong, James E. Dunford, Renzo Guerrini, Adrian L. Harris, Jane Hartley, Georg Hollander, Kassim Javaid, Maureen Kane, Deirdre Kelly, Dominic Kelly, Samantha J. L. Knight, Alexandra Y. Kreins, Erika M. Kvikstad, Craig B. Langman, Tracy Lester, Kate E. Lines, Simon R. Lord, Xin Lu, Sahar Mansour, Adnan Manzur, Reza Maroofian, Brian Marsden, Joanne Mason, Simon J. McGowan, Davide Mei, Hana Mlcochova, Yoshiko Murakami, Andrea H. Németh, Steven Okoli, Elizabeth Ormondroyd, Lilian Bomme Ousager, Jacqueline Palace, Smita Y. Patel, Melissa M. Pentony, Chris Pugh, Aboulfazl Rad, Archana Ramesh, Simone G. Riva, Irene Roberts, Noémi Roy, Outi Salminen, Kyleen D. Schilling, Caroline Scott, Arjune Sen, Conrad Smith, Mark Stevenson, Rajesh V. Thakker, Stephen R. F. Twigg, Holm H. Uhlig, Richard van Wijk, Barbara Vona, Steven Wall, Jing Wang, Hugh Watkins, Jaroslav Zak, Anna H. Schuh, Usha Kini, Andrew O. M. Wilkie, Niko Popitsch, Jenny C. Taylor
Publikováno v:
Genome Medicine, Vol 15, Iss 1, Pp 1-25 (2023)
Abstract Background Whole genome sequencing is increasingly being used for the diagnosis of patients with rare diseases. However, the diagnostic yields of many studies, particularly those conducted in a healthcare setting, are often disappointingly l
Externí odkaz:
https://doaj.org/article/c9f00f4d0c70402d8c69f3f7e4981fbc
Autor:
Akiko Hashimoto, Jiaqi Gao, Yuki Kanome, Yukihiro Ogawa, Masaharu Nakatsu, Masahiro Kohno, Koji Fukui
Publikováno v:
BMC Nephrology, Vol 23, Iss 1, Pp 1-13 (2022)
Abstract Background The number of chronic kidney disease (CKD) patients continues to increase worldwide. CKD patients need to take phosphate binders to manage serum phosphorus concentrations. Currently, several types of phosphate binder, including la
Externí odkaz:
https://doaj.org/article/800f7f8fa06943479db0a590d4cd4120
Autor:
Gaku Tsuji, Akiko Hashimoto-Hachiya, Tomoyo Matsuda-Taniguchi, Ayako Takai-Yumine, Masaki Takemura, Xianghong Yan, Masutaka Furue, Takeshi Nakahara
Publikováno v:
Frontiers in Immunology, Vol 13 (2022)
Interleukin (IL)-37 suppresses systemic and local inflammation. It is expressed in the epidermis, the external layer of the skin, and is decreased in inflammatory skin diseases including atopic dermatitis (AD) and psoriasis. Therefore, an agent appli
Externí odkaz:
https://doaj.org/article/9711a9cfe9414d359a155b1bb3275706
Autor:
Masutaka Furue, Dugarmaa Ulzii, Takeshi Nakahara, Gaku Tsuji, Kazuhisa Furue, Akiko Hashimoto-Hachiya, Makiko Kido-Nakahara
Publikováno v:
Allergology International, Vol 69, Iss 3, Pp 412-416 (2020)
Atopic dermatitis (AD) is a common eczematous skin disorder characterized by skin inflammation, barrier disruption, chronic pruritus and marked scratching. Th2 cytokines, especially IL-13, play a pathogenic role in AD. IL-13 signals via a heterodimer
Externí odkaz:
https://doaj.org/article/d85247d5c0504bf8bfba455a73a0ffac
Publikováno v:
European Journal of Case Reports in Internal Medicine (2021)
Angioimmunoblastic T-cell lymphoma (AITL) can be complicated by Epstein-Barr virus (EBV)-positive B-cell lymphoma. B-cell lymphoma may develop simultaneously at the time of AITL diagnosis or after treatment for AITL. EBV-associated B-cell lymphoma ca
Externí odkaz:
https://doaj.org/article/ce774f55475b42b7b6d8a13669d7e886
Publikováno v:
Clinical Case Reports, Vol 9, Iss 7, Pp n/a-n/a (2021)
Abstract A man with chronic kidney disease (CKD) under hemodialysis was diagnosed with acute promyelocytic leukemia (APL). He received arsenic trioxide as a single agent and achieved complete molecular remission without severe adverse events. Arsenic
Externí odkaz:
https://doaj.org/article/1363783f75174ed7b6117e3a91bfbb86
Autor:
Akiko Hashimoto, John W. Traphagan
The Japanese family is at a crossroads of demographic change and altered cultural values. While the population of children has been shrinking and that of elders rising, attitudes about rights and responsibilities within the family have changed signif
Autor:
Satoshi Wakita, Atsushi Marumo, Kaoru Morita, Shinichi Kako, Takashi Toya, Yuho Najima, Noriko Doki, Junya Kanda, Junya Kuroda, Shinichiro Mori, Atsushi Satake, Kensuke Usuki, Toshimitsu Ueki, Nobuhiko Uoshima, Yutaka Kobayashi, Eri Kawata, Kazutaka Nakayama, Yuhei Nagao, Katsuhiro Shono, Motoharu Shibusawa, Jiro Tadokoro, Masao Hagihara, Hitoji Uchiyama, Naoyuki Uchida, Yasushi Kubota, Shinya Kimura, Hisao Nagoshi, Tatsuo Ichinohe, Saiko Kurosawa, Sayuri Motomura, Akiko Hashimoto, Hideharu Muto, Eriko Sato, Masao Ogata, Kenjiro Mitsuhashi, Jun Ando, Haruko Tashiro, Masahiro Sakaguchi, Shunsuke Yui, Kunihito Arai, Tomoaki Kitano, Miho Miyata, Haruka Arai, Masayuki Kanda, Kako Itabashi, Takahiro Fukuda, Yoshinobu Kanda, Hiroki Yamaguchi
Publikováno v:
Cancer Science. 114:1297-1308
Nucleophosmin1 (NPM1) mutations are the most frequently detected gene mutations in acute myeloid leukemia (AML) and are considered a favorable prognostic factor. We retrospectively analyzed the prognosis of 605 Japanese patients with de novo AML, inc
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::5fb77020bb20fa0e906e6a89c687d30c
https://doi.org/10.1111/cas.15720
https://doi.org/10.1111/cas.15720
Publikováno v:
Acta Dermato-Venereologica, Vol 98, Iss 10, Pp 918-923 (2018)
Aryl hydrocarbon receptor (AHR) is a chemical sensor that is expressed abundantly in epidermal keratinocytes. Oxidative AHR ligands induce the production of reactive oxygen species. However, antioxidant AHR ligands inhibit reactive oxygen species gen
Externí odkaz:
https://doaj.org/article/cb3350c3711f45b9b9791278a26804e7