Zobrazeno 1 - 9
of 9
pro vyhledávání: '"Akihito Nonoyama"'
Publikováno v:
Nature Communications, Vol 13, Iss 1, Pp 1-13 (2022)
Non-heme iron and α-ketoglutarate-dependent (Fe/αKG) oxygenases have attracted attention for their application as biocatalysts due to their flexibility and high efficiency. Here, the authors show the biochemical and structural characterizations of
Externí odkaz:
https://doaj.org/article/e00ab63426854cd7a09fe5b5accee271
Autor:
Huiping Zhang, Akihito Nonoyama, Ikuro Abe, Fumiaki Hayashi, Hui Tao, Takahiro Mori, Shuang Lyu, He-Ping Chen, Shoukou Lee
Non-heme iron and α-ketoglutarate-dependent (Fe/αKG) oxygenases catalyze various oxidative biotransformations. Due to their catalytic flexibility and high efficiency, Fe/αKG oxygenases have attracted keen attention for their application as biocata
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::23457551ea88d9d8ecb567924e240c61
https://doi.org/10.21203/rs.3.rs-736558/v1
https://doi.org/10.21203/rs.3.rs-736558/v1
Autor:
Ando Takeya, Fukuda Nobuhisa, Yoshio Nakai, Satoshi Suzuki, Hiroaki Tanaka, Shoukou Lee, Akihito Nonoyama, Kazuhiko Takahashi
Publikováno v:
Organic Process Research & Development. 23:499-511
Here, we describe an efficient and cost-effective telescoping route to the pharmacologically active form (2), which is a key manufacturing precursor to a novel renin inhibitor for the treatment of ...
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::bec276388cd89c5142f63611f0228dd6
https://doi.org/10.1021/acs.oprd.8b00414
https://doi.org/10.1021/acs.oprd.8b00414
Publikováno v:
Tetrahedron. 73:1517-1521
An anti-selective catalytic asymmetric nitroaldol reaction was implemented in a continuous-flow reaction platform for the synthesis of a key intermediate of a drug candidate. The requisite solid-phase catalyst was readily prepared by mixing an amide-
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::4c0bbad029ed85f9d687b95e0e8ec6f3
https://doi.org/10.1016/j.tet.2017.01.066
https://doi.org/10.1016/j.tet.2017.01.066
Publikováno v:
Tetrahedron Letters. 57:1815-1819
A Nd/Na heterobimetallic complex prepared from an amide-based chiral ligand, Nd alkoxide, and NaHMDS is a highly efficient heterogeneous catalyst for an anti-selective catalytic asymmetric nitroaldol reaction. Nd alkoxide is sensitive to moisture, ex
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::95a27af0854a3a67fc39bdef17179c6c
https://doi.org/10.1016/j.tetlet.2016.03.041
https://doi.org/10.1016/j.tetlet.2016.03.041
Publikováno v:
ChemInform. 47
A Nd/Na heterobimetallic complex prepared from an amide-based chiral ligand, Nd alkoxide, and NaHMDS is a highly efficient heterogeneous catalyst for an anti-selective catalytic asymmetric nitroaldol reaction. Nd alkoxide is sensitive to moisture, ex
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::1928cf86e60f0a8c3171b33243d8df30
https://doi.org/10.1002/chin.201631064
https://doi.org/10.1002/chin.201631064
Autor:
Chunxiang Kuang, Masaaki Suzuki, Ikuya Ban, Akihito Nonoyama, Hisashi Doi, Hideo Tsukada, Kengo Sumi, Takamitsu Hosoya
Publikováno v:
Chemistry - A European Journal. 15:4165-4171
A new synthetic methodology for the rapid methylation and fluoromethylation on aryl and alkenyl frameworks by using methyl and fluoromethyl iodide with an organoboronic acid ester has been developed under the simple and mild conditions of [Pd(2)(dba)
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::06474cc5663d931bba587e8d586a766a
https://doi.org/10.1002/chem.200801974
https://doi.org/10.1002/chem.200801974
Publikováno v:
Tetrahedron. 63:5886-5894
A tricyclic model ether compound comprising 6/8/6 ether rings was synthesized via a new route including conjugate addition to form a symmetric eight-membered ether-ketone with syn/trans stereochemistry in selective manner. The corresponding vinyl tri
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::72bcbd094138c6bcb73966006e2a48b3
https://doi.org/10.1016/j.tet.2007.03.012
https://doi.org/10.1016/j.tet.2007.03.012
Autor:
Hisashi, Doi, Ikuya, Ban, Akihito, Nonoyama, Kengo, Sumi, Chunxiang, Kuang, Takamitsu, Hosoya, Hideo, Tsukada, Masaaki, Suzuki
Publikováno v:
Chemistry (Weinheim an der Bergstrasse, Germany). 15(16)
A new synthetic methodology for the rapid methylation and fluoromethylation on aryl and alkenyl frameworks by using methyl and fluoromethyl iodide with an organoboronic acid ester has been developed under the simple and mild conditions of [Pd(2)(dba)
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::293084c3b128ddce4f53824c393aa913
https://pubmed.ncbi.nlm.nih.gov/19283823
https://pubmed.ncbi.nlm.nih.gov/19283823