Zobrazeno 1 - 10 of 12 pro vyhledávání: '"Akihisa Toratani"'
1
Effects of Bradykinin on Prostaglandin I 2 Synthesis in Human Vascular Endothelial Cells
Autor: Takeshi Kawahara, Sumio Komatsu, Toshiyuki Tamagaki, Masao Nakagawa, Hajime Tsuji, Shohei Sawada, Yusuke Tada, Akihisa Toratani, Yoshihito Kono, Tadashi Higaki, Hitoshi Imamura, Naoaki Akamatsu, Toshiyuki Sato, Yutaka Tsuda, Seiki Yamasaki
Publikováno v: Hypertension. 36:201-207
Abstract —The effects of bradykinin on the regulatory mechanisms of prostacyclin synthesis in endothelial cells were investigated in association with intracellular Ca 2+ kinetics, cytosolic phospholipase A 2 (cPLA 2 ) activity, and mRNA expression
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d15d7e5211fe4aad65dc206b3cac24bf
https://doi.org/10.1161/01.hyp.36.2.201
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2
A Role of Protein Kinase C in the Regulation of Cytosolic Phospholipase A2 in Bradykinin-Induced PGI2 Synthesis by Human Vascular Endothelial Cells
Autor: Yutaka Tsuda, Yusuke Tada, Masao Nakagawa, Tadashi Higaki, Seiki Yamasaki, Toshiyuki Sato, Toshiyuki Tamagaki, Shohei Sawada, Hajime Tsuji, Akihisa Toratani, Yoshihito Kono, Naoaki Akamatsu, Hitoshi Imamura, Sumio Komatsu
Publikováno v: Microvascular Research. 58:144-155
The purpose of this study was to elucidate the mechanism by which bradykinin (BK) enhances prostacyclin (PGI 2 ) production in human umbilical vein endothelial cells (HUVEC). BK-induced enhancement of PGI 2 synthesis was observed in a dose- and time-
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::7ed17fb1cec5bd6fb491c36d18b6460e
https://doi.org/10.1006/mvre.1999.2163
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3
Interleukin-1α Stimulated Prostacyclin Release by Increasing Gene Transcription of Prostaglandin H Synthase and Phospholipase A2 in Human Vascular Endothelial Cells
Autor: Masao Nakagawa, Sumio Komatsu, Shohei Sawada, Hitoshi Imamura, Hajime Tsuji, Seiki Yamasaki, Akihisa Toratani, Toshiyuki Tamagaki, Toshiyuki Sato, Naoaki Akamatsu, Tadashi Higaki, Yoshihito Kono, Katsumi Nakagawa, Yusuke Tada
Publikováno v: Journal of Cardiovascular Pharmacology. 33:843-851
This study was conducted to evaluate the effects of interleukin-1alpha (IL-1alpha) on prostacyclin (PGI2) production in cultured human vascular endothelial cells in association with intracellular Ca2+, inositol 1,4,5-trisphosphate (IP3), and with pro
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::5cbc3814d8a22ec64370d90a3140d932
https://doi.org/10.1097/00005344-199906000-00003
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5
The Mechanism of Thrombin Induced Prostaglandin I2 (PGI2) Enhancement in Human Umbilical Vein Endothelial Cells with Reference to the Gene Expression of PGI2 Related Enzymes and Calcium Ion Kinetics
Autor: Kazuharu Kato, Seiki Yamazaki, Hajime Tsuji, Toshiyuki Sato, Akihisa Toratani, Sumio Komatsu, Yusuke Tada, Naoaki Akamatsu, Masao Nakagawa, Toshiyuki Tamagaki, Hitoshi Imamura, Shohei Sawada, Tadashi Higaki, Masahito Yamagami, Katsumi Nakagawa
Publikováno v: Japanese Journal of Thrombosis and Hemostasis. 8:112-121
Signal induction and molecular mechanisms of the thrombin induced prostaglandin I2 (PGI2) synthesis in human umbilical vein endothelial cells (HUVEC) were investigated in association with the intra Ca2+ and the gene expression of prostaglandin H2 syn
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::d1eff5156cd422f42b1c088cd55e5731
https://doi.org/10.2491/jjsth.8.112
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6
Effects of high-density lipoproteins on intracellular pH and proliferation of human vascular endothelial cells
Autor: Hajime Tsuji, Katsumi Nakagawa, Akihisa Toratani, Shohei Sawada, Toshiyuki Sato, Hitoshi Imamura, Sumio Komatsu, Masao Nakagawa, Kazuharu Kato, Katsumi Yamamoto, Toshiyuki Tamagaki, Tadashi Higaki, Seiki Yamasaki, Naoaki Akamatsu, Kaoru Shirai, Kyoichiro Kobayashi, Keizo Yamada, Mashahito Yamagami, Y. Tada
Publikováno v: Atherosclerosis. 123:73-82
We investigated the effects of high-density lipoprotein (HDL) on the intracellular pH ([pH] i ), and on the proliferation of human vascular endothelial cells (HUVEC), as well as on their production of prostacyclin (PGI 2 ). The [pH] i was slightly ac
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b5d9404f0193d9100e98d4b3b57c1eb1
https://doi.org/10.1016/0021-9150(95)05774-9
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7
Effect of probucol on intracellular pH and proliferation of human vascular endothelial cells
Autor: Masao Nakagawa, Yutaka Tsuda, Shohei Sawada, Hitoshi Imamura, Y. Tada, Hajime Tsuji, Naoaki Akamatsu, Yoshihito Kono, Seiki Yamasaki, Akihisa Toratani, Tadashi Higaki, Sumio Komatsu, Toshiyuki Sato, Toshiyuki Tamagaki
Publikováno v: Journal of pharmacological and toxicological methods. 41(1)
We investigated the effect of probucol on the intracellular pH ([pH]i) and proliferation of human umbilical vein endothelial cells (HUVEC), as well as their production of prostacyclin (PGI2). The addition of probucol produced a biphasic shift in [pH]
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::1e7cf70e0ace93c97d7b0f2834f6477b
https://pubmed.ncbi.nlm.nih.gov/10507756
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