Zobrazeno 1 - 10
of 145
pro vyhledávání: '"Akihiro Tai"'
Autor:
Takeru Koga, Naoaki Kawahara, Mei Aburada, Asako Ono, Shiori Mae, Aina Yoshida, Yuji Iwaoka, Hideyuki Ito, Akihiro Tai
Publikováno v:
Molecules, Vol 29, Iss 1, p 69 (2023)
2-O-Alkyl-l-ascorbic acids and 3-O-alkyl-l-ascorbic acids were synthesized, and their degranulation inhibitory activities were evaluated. Among ascorbic acid derivatives with butyl, octyl, dodecyl, hexadecyl, and octadecyl groups introduced at the C-
Externí odkaz:
https://doaj.org/article/9a22bb2fa1d54289b1fc6338bc69a30b
Publikováno v:
Molecules, Vol 27, Iss 22, p 7670 (2022)
Isorhamnetin-3-O-glucoside and astragalin, flavonol glucosides, were isolated from the petals of Paeonia lactiflora as neurite outgrowth-promoting compounds. Isoquercitrin, formed by demethylating the B ring of isorhamnetin-3-O-glucoside or by adding
Externí odkaz:
https://doaj.org/article/9625543d1d64442f9ed53e0a6227e0ee
Autor:
Takeru Koga, Akihiro Tai
Publikováno v:
Nutrients, Vol 14, Iss 7, p 1422 (2022)
Cockscomb hydrolysate was found to have neurite outgrowth-promoting activity in PC12 cells. To investigate the neurite outgrowth-promoting compounds derived from cockscomb hydrolysate, bioassay-guided purification was carried out. Purified active fra
Externí odkaz:
https://doaj.org/article/53acee1f77e247a18b6a248eb6f7cd82
Publikováno v:
Molecules, Vol 26, Iss 15, p 4684 (2021)
Allergy is an excessive immune response to a specific antigen. Type I allergies, such as hay fever and food allergies, have increased significantly in recent years and have become a worldwide problem. We previously reported that an ascorbic acid deri
Externí odkaz:
https://doaj.org/article/b8a9626d4e04433ab3042eb3cd7cbb7e
Autor:
Kaori Miura, Akihiro Tai
Publikováno v:
Biochemistry and Biophysics Reports, Vol 10, Iss C, Pp 232-236 (2017)
Ascorbic acid (AA) has been reported as a treatment for cancer patients. Intravenous (iv) administration of high-dose AA increases plasma AA levels to pharmacologic concentrations and generates reactive oxygen species (ROS) to exert anti-tumor activi
Externí odkaz:
https://doaj.org/article/abfdf93110d940bd874fd4b5700a9b39
Publikováno v:
Molecules, Vol 25, Iss 20, p 4748 (2020)
In the current super-aging society, the establishment of methods for prevention and treatment of Alzheimer’s disease (AD) is an urgent task. One of the causes of AD is thought to be a decrease in the revel of nerve growth factor (NGF) in the brain.
Externí odkaz:
https://doaj.org/article/286e73d801cb47379b20eeae994efb57
Publikováno v:
Molecules, Vol 22, Iss 12, p 2202 (2017)
2-O-α-d-Glucopyranosyl-l-ascorbic acid (AA-2G) is one of the stable ascorbic acid (AA) derivatives known as provitamin C agents. We have previously synthesized two types of monoacylated derivatives of AA-2G, 6-O-acyl-2-O-α-d-glucopyranosyl-l-ascorb
Externí odkaz:
https://doaj.org/article/809b9a2de3ab4505a00a753626330c7c
Publikováno v:
Journal of Pharmacological Sciences, Vol 91, Iss 2, Pp 158-162 (2003)
Bursaphelenchus xylophilus (B. xylophilus) is a pine wood nematode that is known to cause pine wilt disease. We report here that B. xylophilus extracts augmented the polyclonal immunoglobulin E (IgE) production induced by lipopolysaccharide (LPS) plu
Externí odkaz:
https://doaj.org/article/ce3a29dd85f34fa0b7b4e20c421f70bc
Autor:
Futoshi Yazama, Akihiro Tai
Publikováno v:
PLoS ONE, Vol 6, Iss 5, p e19387 (2011)
BackgroundHeat shock severely affects sperm production (spermatogenesis) and results in a rapid loss of haploid germ cells, or in other words, sperm formation (spermiogenesis) is inhibited. However, the mechanisms behind the effects of heat shock on
Externí odkaz:
https://doaj.org/article/49de893cced34d049a1706cc0f14a5a2
Publikováno v:
Records of Natural Products. :645-650