Výsledky vyhledávání - "Akihiro Otuki"

Hsp70 promotes maturation of uromodulin mutants that cause familial juvenile hyperuricemic nephropathy and suppresses cellular damage

Autor: Sulistiyati Bayu Utami, Ryo Endo, Toshihiro Hamada, Tomomi Notsu, Hiroyuki Minato, Koji Komatsu, Yuji Nakayama, Yasuaki Shirayoshi, Kazuhiro Yamamoto, Shinichi Okada, Haruaki Ninomiya, Akihiro Otuki, Ichiro Hisatome

Publikováno v: Clinical and experimental nephrology. 26(6)

Familial juvenile hyperuricemic nephropathy (FJHN) is an autosomal dominant disorder caused by mutations in UMOD. Here we studied effects of genetic expression and pharmacological induction of Hsp70 on the UMOD mutants C112Y and C217G.We expressed wi

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::09e0b68c3c5eaaebc0cd4590a117bd42
https://pubmed.ncbi.nlm.nih.gov/35212881

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