Zobrazeno 1 - 10
of 33
pro vyhledávání: '"Akihiro Nyuya"'
Autor:
Kazuya Yasui, Toshiaki Toshima, Ryo Inada, Yuzo Umeda, Shuya Yano, Hiroaki Tanioka, Akihiro Nyuya, Toshiyoshi Fujiwara, Takeshi Yamada, Yoshio Naomoto, Ajay Goel, Takeshi Nagasaka
Publikováno v:
Molecular Cancer, Vol 23, Iss 1, Pp 1-8 (2024)
Abstract This study investigates methylation patterns in circulating cell-free DNA (ccfDNA) for their potential role in colorectal cancer (CRC) detection and the monitoring of treatment response. Through methylation microarrays and quantitative PCR a
Externí odkaz:
https://doaj.org/article/1c14b70e34c74e49905948114b61e039
Autor:
Fumitaka Taniguchi, Akihiro Nyuya, Toshiaki Toshima, Kazuya Yasui, Yoshiko Mori, Makoto Okawaki, Hiroyuki Kishimoto, Yuzo Umeda, Toshiyoshi Fujiwara, Hiroaki Tanioka, Yoshiyuki Yamaguchi, Ajay Goel, Takeshi Nagasaka
Publikováno v:
Future Science OA, Vol 7, Iss 10 (2021)
Aim: To evaluate whether PCR-reverse sequence-specific oligonucleotide can examine the concordance between liquid biopsy and metastatic lesions with acquired resistance. Materials & methods: We examined acquired mutations in chemoresistant lesions an
Externí odkaz:
https://doaj.org/article/ea0e4ef415a24da2a5f05b5e43157ddd
Autor:
Yuko Takehara, Takeshi Nagasaka, Akihiro Nyuya, Tomoko Haruma, Junko Haraga, Yoshiko Mori, Keiichiro Nakamura, Toshiyoshi Fujiwara, C. Richard Boland, Ajay Goel
Publikováno v:
Journal of Translational Medicine, Vol 16, Iss 1, Pp 1-11 (2018)
Abstract Background To screen tumors with microsatellite instability (MSI) arising due to DNA mismatch repair deficiency (dMMR), a panel of five quasi-monomorphic mononucleotide-repeat markers amplified in a multiplex PCR (Pentaplex) are commonly use
Externí odkaz:
https://doaj.org/article/5984a34338574fbd8b6b61c76f1dce1f
Autor:
Tomoko Haruma, Takeshi Nagasaka, Keiichiro Nakamura, Junko Haraga, Akihiro Nyuya, Takeshi Nishida, Ajay Goel, Hisashi Masuyama, Yuji Hiramatsu
Publikováno v:
PLoS ONE, Vol 13, Iss 4, p e0195655 (2018)
The molecular characterization of endometrial cancer (EC) can facilitate identification of various tumor subtypes. Although EC patients with POLE mutations reproducibly demonstrate better prognosis, the outcome of patients with microsatellite instabi
Externí odkaz:
https://doaj.org/article/8a6e972d04bd4648a1d14b396e0f44fc
Autor:
Hiroaki Tanioka, Makoto Okawaki, Shuya Yano, Tomomi Yoshimitsu, Kikue Tokuda, Akihiro Nyuya, Yoshiyuki Yamaguchi, Takeshi Nagasaka
Publikováno v:
Oncology Letters. 25
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::803e96f78c33fa91a307f59ba5f61550
https://doi.org/10.3892/ol.2023.13684
https://doi.org/10.3892/ol.2023.13684
Autor:
Toshiaki Toshima, Hiroaki Tanioka, Yoshiko Mori, Takehiro Tanaka, Kazuya Yasui, Keisuke Kimura, Yuzo Umeda, Toshiyoshi Fujiwara, Akihiro Nyuya, Shuya Yano, Takeshi Nagasaka
Publikováno v:
Oncology.
Introduction: Gastric cancer is divided into four subtypes by their molecular features linked with genetic alterations, e.g., Epstein-Barr virus (EBV), microsatellite instability-high (MSI-high), chromosomal instability (CIN), and genomically stable
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::999f7ebd8f428978c949cd92562a4ea2
https://pubmed.ncbi.nlm.nih.gov/36244328
https://pubmed.ncbi.nlm.nih.gov/36244328
Autor:
Akihiro Nyuya, Junko Haraga, Tomoko Haruma, Hisashi Masuyama, Keiichiro Nakamura, Takeshi Nagasaka
Publikováno v:
Anticancer Research. 40:3811-3818
Background/aim The objective of this study was to determine the molecular and clinicopathological features, as well as the prognosis of patients with endometrial cancer (EC) having prior malignancy (second primary EC: SPEC) compared with those withou
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::cc42ba9c3a96b0524daa1349790b55fe
https://doi.org/10.21873/anticanres.14370
https://doi.org/10.21873/anticanres.14370
Autor:
Tomomi Yoshimitsu, Kikue Tokuda, Takeshi Nagasaka, Hiroaki Tanioka, Makoto Okawaki, Shuya Yano, Akihiro Nyuya, Yosuke Katata
Background: The neutrophil-to-lymphocyte ratio (NLR) is a well-known prognostic marker for gastric cancer (GC) patients. However, for GC patients treated with palliative chemotherapy, the prognostic value of NLR remains obscure. Therefore, we evaluat
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::604f2f78f92c00a6ef7bb21cf98dae3f
https://doi.org/10.21203/rs.3.rs-960283/v1
https://doi.org/10.21203/rs.3.rs-960283/v1
Autor:
Takashi Kawai, Akihiro Nyuya, Toshiyoshi Fujiwara, Yuzo Umeda, Takeshi Nagasaka, Toshiaki Toshima, Fumitaka Taniguchi, Tomokazu Fuji, Kazuya Yasui, Kazuhiro Yoshida, Ajay Goel
Publikováno v:
International Journal of Cancer. 144:2169-2180
Because of the different forms of circulating miRNAs in plasma, Argonaute2 (Ago2)-miRNAs and extracellular vesicles (EV-miRNAs), we examined the two forms of extracellular miRNAs in vitro and developed a unique methodology to detect circulating Ago2-
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::122ba4a90acae9972ec907d2b3ad9c1a
https://doi.org/10.1002/ijc.31960
https://doi.org/10.1002/ijc.31960
Autor:
Toshiyoshi Fujiwara, Yoshiko Mori, Akihiro Nyuya, Ajay Goel, Hiroaki Tanioka, Hiroyuki Kishimoto, Yoshiyuki Yamaguchi, Yuzo Umeda, Makoto Okawaki, Kazuya Yasui, Toshiaki Toshima, Fumitaka Taniguchi, Takeshi Nagasaka
Publikováno v:
Future Science OA
Aim: To evaluate whether PCR-reverse sequence-specific oligonucleotide can examine the concordance between liquid biopsy and metastatic lesions with acquired resistance. Materials & methods: We examined acquired mutations in chemoresistant lesions an
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c1344a11e4a5951b5547e70e270fc37a
https://pubmed.ncbi.nlm.nih.gov/34840814
https://pubmed.ncbi.nlm.nih.gov/34840814