Zobrazeno 1 - 10
of 47
pro vyhledávání: '"Akihiro Muto"'
Autor:
Takatsune Shimizu, Eiji Sugihara, Hideyuki Takeshima, Hiroyuki Nobusue, Rui Yamaguchi, Sayaka Yamaguchi-Iwai, Yumi Fukuchi, Toshikazu Ushijima, Akihiro Muto, Hideyuki Saya
Publikováno v:
Cells, Vol 11, Iss 22, p 3614 (2022)
Novel therapeutic targets are needed to better treat osteosarcoma, which is the most common bone malignancy. We previously developed mouse osteosarcoma cells, designated AX (accelerated bone formation) cells from bone marrow stromal cells. AX cells h
Externí odkaz:
https://doaj.org/article/de4a4d3f2f8c4e9385400a22d71adffb
Autor:
Arisa Ueki, Takatsune Shimizu, Kenta Masuda, Sayaka I Yamaguchi, Tomoki Ishikawa, Eiji Sugihara, Nobuyuki Onishi, Shinji Kuninaka, Keita Miyoshi, Akihiro Muto, Yoshiaki Toyama, Kouji Banno, Daisuke Aoki, Hideyuki Saya
Publikováno v:
PLoS ONE, Vol 7, Iss 11, p e50621 (2012)
Osteosarcoma is a high-grade malignant bone tumor that manifests ingravescent clinical behavior. The intrinsic events that confer malignant properties on osteosarcoma cells have remained unclear, however. We previously established two lines of mouse
Externí odkaz:
https://doaj.org/article/b952486073264347888952b05644f1bc
Autor:
Takatsune Shimizu, Hideyuki Saya, Akihiro Muto, Koichi Matsuo, Yumi Fukuchi, Kenta Maki, Nobuyuki Onishi, Sayaka Yamaguchi-Iwai, Hiroyuki Nobusue, Eiji Sugihara, Walied A. Kamel
(A, B) Weight of AXT cell-derived tumors formed in mice treated with saline or simvastatin administered either by intraperitoneal injection (40 mg/kg per day) (A) or by oral gavage (80 mg/kg per day) (B) Data are means {plus minus} SD. (C) Viability
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::172fbff31b825b2b411b140fd92c13f6
https://doi.org/10.1158/1535-7163.22508217.v1
https://doi.org/10.1158/1535-7163.22508217.v1
Autor:
Takatsune Shimizu, Hideyuki Saya, Akihiro Muto, Koichi Matsuo, Yumi Fukuchi, Kenta Maki, Nobuyuki Onishi, Sayaka Yamaguchi-Iwai, Hiroyuki Nobusue, Eiji Sugihara, Walied A. Kamel
Supplementary Figure Legends.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::095306695057ff9eb85b085d13825930
https://doi.org/10.1158/1535-7163.22508226.v1
https://doi.org/10.1158/1535-7163.22508226.v1
Autor:
Hideyuki Saya, Akihiro Muto, Yoshiaki Toyama, Junya Toguchida, Toshihiro Nagai, Yumi Fukuchi, Koichi Matsuo, Junzo Kamei, Hiroko Ikeda, Nobuyuki Onishi, Satoru Osuka, Tatsuyuki Chiyoda, Tomoki Ishikawa, Arisa Ueki, Walied Kamel, Yuko Koyama, Sakura Tamaki, Sayaka Yamaguchi-Iwai, Eiji Sugihara, Takatsune Shimizu
Supplementary Figure S4: (A,B) Viable AXT cells after the treatment of chemotherapeutic agents. (C) Representative flow cytometric analysis of γ-H2AX abundance in AXT cells as described in Fig.4E. (D) Immunofluorescence analysis of γ-H2
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::63c4bece361bd6c77a17b75797f066b5
https://doi.org/10.1158/0008-5472.22404185.v1
https://doi.org/10.1158/0008-5472.22404185.v1
Autor:
Hideyuki Saya, Akihiro Muto, Yoshiaki Toyama, Junya Toguchida, Toshihiro Nagai, Yumi Fukuchi, Koichi Matsuo, Junzo Kamei, Hiroko Ikeda, Nobuyuki Onishi, Satoru Osuka, Tatsuyuki Chiyoda, Tomoki Ishikawa, Arisa Ueki, Walied Kamel, Yuko Koyama, Sakura Tamaki, Sayaka Yamaguchi-Iwai, Eiji Sugihara, Takatsune Shimizu
Supplementary Table S1. Sequences of primers and predicted product sizes for real-time RT-PCR analysis
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::27716f09845b6d14fdf06f221bb201af
https://doi.org/10.1158/0008-5472.22404173
https://doi.org/10.1158/0008-5472.22404173
Autor:
Hideyuki Saya, Akihiro Muto, Yoshiaki Toyama, Junya Toguchida, Toshihiro Nagai, Yumi Fukuchi, Koichi Matsuo, Junzo Kamei, Hiroko Ikeda, Nobuyuki Onishi, Satoru Osuka, Tatsuyuki Chiyoda, Tomoki Ishikawa, Arisa Ueki, Walied Kamel, Yuko Koyama, Sakura Tamaki, Sayaka Yamaguchi-Iwai, Eiji Sugihara, Takatsune Shimizu
Supplementary Information. Supplementary Materials and Methods and Supplementary Figure Legends
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::aa8585967dc698bbaa868a8ff362520d
https://doi.org/10.1158/0008-5472.22404176.v1
https://doi.org/10.1158/0008-5472.22404176.v1
Autor:
Hideyuki Saya, Akihiro Muto, Yoshiaki Toyama, Junya Toguchida, Toshihiro Nagai, Yumi Fukuchi, Koichi Matsuo, Junzo Kamei, Hiroko Ikeda, Nobuyuki Onishi, Satoru Osuka, Tatsuyuki Chiyoda, Tomoki Ishikawa, Arisa Ueki, Walied Kamel, Yuko Koyama, Sakura Tamaki, Sayaka Yamaguchi-Iwai, Eiji Sugihara, Takatsune Shimizu
Supplementary movie S1
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::04741b9ef236e3ef6ccbd5475d6050a3
https://doi.org/10.1158/0008-5472.22404167.v1
https://doi.org/10.1158/0008-5472.22404167.v1
Autor:
Kaori Saitoh, Oltea Sampetrean, Hiroyuki Nobusue, Sayaka Yamaguchi-Iwai, Kiyomi Kimura, Tomoyoshi Soga, Takatsune Shimizu, Eiji Sugihara, Hideyuki Saya, Akihiro Muto, Yumi Fukuchi, Keiko Kato, Yuji Otsuki
Publikováno v:
Journal of orthopaedic research : official publication of the Orthopaedic Research SocietyREFERENCES. 39(12)
Osteosarcoma is the most common high-grade malignancy of bone, and novel therapeutic options are urgently required. Previously, we developed mouse osteosarcoma AXT cells that can proliferate both under adherent and nonadherent conditions. Based on me
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::824903b5e6451045888224f19d624b96
https://pubmed.ncbi.nlm.nih.gov/33751653
https://pubmed.ncbi.nlm.nih.gov/33751653
Autor:
Takatsune Shimizu, Akihiro Muto, Yumi Fukuchi, Walied A. Kamel, Sayaka Yamaguchi-Iwai, Hideyuki Saya
Publikováno v:
Cancer Science
Osteosarcoma is the most common type of primary bone tumor, and novel therapeutic approaches for this disease are urgently required. To identify effective agents, we screened a panel of Food and Drug Administration (FDA)‐approved drugs in AXT cells
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::77e000e494d6fb1ffb15d4796ef72f6d
https://doi.org/10.1111/cas.13304
https://doi.org/10.1111/cas.13304