Zobrazeno 1 - 10
of 99
pro vyhledávání: '"Akihiro Kurimasa"'
Autor:
Kazuo Tomita, Yoshikazu Kuwahara, Kento Igarashi, Junichi Kitanaka, Nobue Kitanaka, Yuko Takashi, Koh-ichi Tanaka, Mehryar Habibi Roudkenar, Amaneh Mohammadi Roushandeh, Akihiro Kurimasa, Yoshihiro Nishitani, Tomoaki Sato
Publikováno v:
Japanese Dental Science Review, Vol 59, Iss , Pp 431-438 (2023)
Patients with neurological diseases, such as schizophrenia, tend to show low K+-Cl- co-transporter 2 (KCC2) levels in the brain. The cause of these diseases has been associated with stress and neuroinflammation. However, since the pathogenesis of the
Externí odkaz:
https://doaj.org/article/e727f14819824679bcf66fd6b2e36fd6
Autor:
Yoshikazu Kuwahara PhD, Kazuo Tomita PhD, Mehryar Habibi Roudkenar PhD, Amaneh Mohammadi Roushandeh PhD, Yusuke Urushihara PhD, Kento Igarashi PhD, Taisuke Nagasawa DDS, Akihiro Kurimasa MD, PhD, Manabu Fukumoto MD, PhD, Tomoaki Sato DDS, PhD
Publikováno v:
Technology in Cancer Research & Treatment, Vol 19 (2020)
Background: Radiation therapy is a highly cost-effective treatment for cancer, but the existence of radio-resistant cells remains the most critical obstacle in radiotherapy. We have been established clinically relevant radioresistant (CRR) cell lines
Externí odkaz:
https://doaj.org/article/43a424dceef7490d9ef73917c96bfa07
Autor:
Yuko Takashi, Kazuo Tomita, Yoshikazu Kuwahara, Hideki Nabika, Kento Igarashi, Taisuke Nagasawa, Akihiro Kurimasa, Manabu Fukumoto, Yoshihiro Nishitani, Tomoaki Sato
Publikováno v:
Data in Brief, Vol 20, Iss , Pp 402-410 (2018)
We present data about mitochondrial DNA (mtDNA) copy number and aquaporin (AQP) gene expression in clinically radioresistant (CRR), ρ0, and their parental cells from human cervical cancer and human tongue squamous cell carcinoma. In both ρ0 and CRR
Externí odkaz:
https://doaj.org/article/e9727d12b96d4928b51bc00a61d2ac2d
Autor:
Kazuo Tomita, Yoshikazu Kuwahara, Yuko Takashi, Kento Igarashi, Taisuke Nagasawa, Hideki Nabika, Akihiro Kurimasa, Manabu Fukumoto, Yoshihiro Nishitani, Tomoaki Sato
Publikováno v:
Tumor Biology, Vol 40 (2018)
Radiation therapy is one of the choices to treat malignant tumors. In radiation therapy, existence of radiation-resistant cell is a major problem to overcome. We established clinically relevant radioresistant cells that had been obtained by exposing
Externí odkaz:
https://doaj.org/article/8c9e911fa93743dfb51b1f6c358d8422
Autor:
Yu-Fen Lin, Hatsumi Nagasawa, John B Little, Takamitsu A Kato, Hung-Ying Shih, Xian-Jin Xie, Paul F Wilson, John R Brogan, Akihiro Kurimasa, David J Chen, Joel S Bedford, Benjamin P C Chen
Publikováno v:
PLoS ONE, Vol 9, Iss 4, p e93579 (2014)
We have examined cell-cycle dependence of chromosomal aberration induction and cell killing after high or low dose-rate γ irradiation in cells bearing DNA-PKcs mutations in the S2056 cluster, the T2609 cluster, or the kinase domain. We also compared
Externí odkaz:
https://doaj.org/article/c5e76ff023f84fe181a3f8854d96a82b
Autor:
Yoshikazu Kuwahara, Kazuo Tomita, Mehryar Habibi Roudkenar, Amaneh Mohammadi Roushandeh, Tomoaki Sato, Akihiro Kurimasa
Publikováno v:
Human Cell. 36:963-971
Autor:
Kento Igarashi, Haruki Iwai, Koh-ichi Tanaka, Yoshikazu Kuwahara, Junichi Kitanaka, Nobue Kitanaka, Akihiro Kurimasa, Kazuo Tomita, Tomoaki Sato
Publikováno v:
Biochemical and Biophysical Research Communications. 612:1-7
Cranial radiation therapy (CRT) is an effective treatment for brain tumors; however, it also causes brain injuries. The pediatric brain is considered especially vulnerable compared to the adult brain; thus, brain injuries caused by CRT may severely a
Autor:
Honoka, Obata, Atsushi B, Tsuji, Katsushi, Kumata, Hitomi, Sudo, Katsuyuki, Minegishi, Kotaro, Nagatsu, Hideo, Takakura, Mikako, Ogawa, Akihiro, Kurimasa, Ming-Rong, Zhang
Publikováno v:
Journal of medicinal chemistry. 65(7)
This study aims to establish new labeling methods for no-carrier-added radio-Pt (
Development of Novel 191Pt-Labeled Hoechst33258: 191Pt Is More Suitable than 111In for Targeting DNA
Autor:
Honoka Obata, Atsushi B. Tsuji, Katsushi Kumata, Hitomi Sudo, Katsuyuki Minegishi, Kotaro Nagatsu, Hideo Takakura, Mikako Ogawa, Akihiro Kurimasa, Ming-Rong Zhang
Publikováno v:
Journal of Medicinal Chemistry. 65:5690-5700
Autor:
Honoka Obata, Akihiro Kurimasa, Tadanori Muraoka, Atsushi B. Tsuji, Katsuya Kondo, Yoshikazu Kuwahara, Katsuyuki Minegishi, Kotaro Nagatsu, Mikako Ogawa, Ming-Rong Zhang
Publikováno v:
Biochemical and biophysical research communications. 637
Auger electrons can induce nanoscale physiochemical damage to DNA. The present study reports a sequential and systematic evaluation of the relationship between DNA damage such as double-strand breaks (DSBs) and the cell cycle for the Auger electron-e