Výsledky vyhledávání - "Akihiro Kamiya"

CysLT2 receptor activation is involved in LTC4-induced lung air-trapping in guinea pigs

Autor: Kazuhito Kawabata, Akihiro Kamiya, Takeshi Nabe, Tomohiko Sekioka, Michiaki Kadode, Manabu Fujita, Yasuo Yonetomi

Publikováno v: European Journal of Pharmacology. 794:147-153

CysLT1 receptors are known to be involved in the pathogenesis of asthma. However, the functional roles of CysLT2 receptors in this condition have not been determined. The purpose of this study is to develop an experimental model of CysLT2 receptor-me

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::c1ceb7e82ca41047fe936457966f8964
https://doi.org/10.1016/j.ejphar.2016.11.036

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Direct evidence for α ether linkage between lignin and carbohydrates in wood cell walls

Autor: Masato Katahira, Takashi Nagata, Akihiro Kamiya, Hiroshi Nishimura, Takashi Watanabe

Publikováno v: Scientific Reports, Vol 8, Iss 1, Pp 1-11 (2018)
Scientific Reports

Cross-linking between lignin and polysaccharide in plant cell-wall determines physical, chemical, and biological features of lignocellulosic biomass. Since Erdmann’s first report in 1866, numerous studies have suggested the presence of a bond betwe

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::5fa8406473fa425017c63f7a2859623b
http://hdl.handle.net/2433/230957

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Effects of ONO-6950, a novel dual cysteinyl leukotriene 1 and 2 receptors antagonist, in a guinea pig model of asthma

Autor: Fumio Nambu, Manabu Fujita, Takafumi Nakao, Hiroaki Nomura, Shinji Nakade, Kazuhito Kawabata, Yasuo Yonetomi, Tetsuya Kitamine, Atsuto Inoue, Shintaro Nakao, Masayuki Murata, Tomohiko Sekioka, Michiaki Kadode, Akihiro Kamiya

Publikováno v: European Journal of Pharmacology. 765:242-248

We assessed in this study the anti-asthmatic effects of ONO-6950, a novel cysteinyl leukotriene 1 (CysLT1) and 2 (CysLT2) receptors dual antagonist, in normal and S-hexyl glutathione (S-hexyl GSH)-treated guinea pigs, and compared these effects to th

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::dff687090db39742cec78e3d8e4d40e9
https://doi.org/10.1016/j.ejphar.2015.08.041

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Leukotriene C4 induces bronchoconstriction and airway vascular hyperpermeability via the cysteinyl leukotriene receptor 2 in S-hexyl glutathione-treated guinea pigs

Autor: Manabu Fujita, Kazuhito Kawabata, Yasuo Yonetomi, Tetsuya Kitamine, Naoya Matsumura, Tomohiko Sekioka, Michiaki Kadode, Akihiro Kamiya

Publikováno v: European Journal of Pharmacology. 754:98-104

Cysteinyl leukotrienes act through G-protein-coupled receptors termed cysteinyl leukotriene 1 (CysLT1) and cysteinyl leukotriene 2 (CysLT2) receptors. However, little is known about the pathophysiological role of CysLT2 receptors in asthma. To elucid

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::aaf67b00db2e6818149a699bedc19b3c
https://doi.org/10.1016/j.ejphar.2015.02.014

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Expression of chromobox homolog 7 (CBX7) is associated with poor prognosis in ovarian clear cell adenocarcinomaviaTRAIL-induced apoptotic pathway regulation

Autor: Eiko Yamamoto, Nozomi Uno, Yuka Sakaguchi, Takashi Takahashi, Tetsuro Nagasaka, Kiyosumi Shibata, Shinya Akatsuka, Kanako Shinjo, Fumitaka Kikkawa, Hiroaki Kajiyama, Yoriko Yamashita, Kaoru Niimi, Akihiro Kamiya, Shinya Toyokuni

Publikováno v: International Journal of Cancer. 135:308-318

Ovarian cancer is the most lethal gynecologic malignancy, and clear cell adenocarcinoma of the ovary (OCCA), in particular, has a relatively poor prognosis among the ovarian cancer subtypes because of its high chemoresistance. Chromobox (CBX) 7 is a

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::3655b247d71ea88b42a9b5983a882c64
https://doi.org/10.1002/ijc.28692

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