Zobrazeno 1 - 10
of 250
pro vyhledávání: '"Akihiro INOUE"'
Autor:
Nobuhide Hayashi, Junya Fukai, Hirokazu Nakatogawa, Hiroshi Kawaji, Ema Yoshioka, Yoshinori Kodama, Kosuke Nakajo, Takehiro Uda, Kentaro Naito, Noriyuki Kijima, Yoshiko Okita, Naoki Kagawa, Yoshinobu Takahashi, Naoya Hashimoto, Hideyuki Arita, Koji Takano, Daisuke Sakamoto, Tomoko Iida, Yoshiki Arakawa, Takeshi Kawauchi, Yukihiko Sonoda, Yuta Mitobe, Kenichi Ishibashi, Masahide Matsuda, Takamune Achiha, Takahiro Tomita, Masahiro Nonaka, Keijiro Hara, Noriyoshi Takebe, Takashi Tsuzuki, Yoshikazu Nakajima, Shiro Ohue, Nobuyuki Nakajima, Akira Watanabe, Akihiro Inoue, Masao Umegaki, Daisuke Kanematsu, Asako Katsuma, Miho Sumida, Tomoko Shofuda, Masayuki Mano, Manabu Kinoshita, Kanji Mori, Naoyuki Nakao, Yonehiro Kanemura
Publikováno v:
Acta Neuropathologica Communications, Vol 12, Iss 1, Pp 1-17 (2024)
Abstract This study aims to elucidate the clinical and molecular characteristics, treatment outcomes and prognostic factors of patients with histone H3 K27-mutant diffuse midline glioma. We retrospectively analyzed 93 patients with diffuse midline gl
Externí odkaz:
https://doaj.org/article/8bd62f025029495cab438e2f08c4ba17
Autor:
Nobuhide Hayashi, Junya Fukai, Hirokazu Nakatogawa, Hiroshi Kawaji, Ema Yoshioka, Yoshinori Kodama, Kosuke Nakajo, Takehiro Uda, Kentaro Naito, Noriyuki Kijima, Yoshiko Okita, Naoki Kagawa, Yoshinobu Takahashi, Naoya Hashimoto, Hideyuki Arita, Koji Takano, Daisuke Sakamoto, Tomoko Iida, Yoshiki Arakawa, Takeshi Kawauchi, Yukihiko Sonoda, Yuta Mitobe, Kenichi Ishibashi, Masahide Matsuda, Takamune Achiha, Takahiro Tomita, Masahiro Nonaka, Keijiro Hara, Noriyoshi Takebe, Takashi Tsuzuki, Yoshikazu Nakajima, Shiro Ohue, Nobuyuki Nakajima, Akira Watanabe, Akihiro Inoue, Masao Umegaki, Daisuke Kanematsu, Asako Katsuma, Miho Sumida, Tomoko Shofuda, Masayuki Mano, Manabu Kinoshita, Kanji Mori, Naoyuki Nakao, Yonehiro Kanemura
Publikováno v:
Acta Neuropathologica Communications, Vol 12, Iss 1, Pp 1-2 (2024)
Externí odkaz:
https://doaj.org/article/672dfe218c974cd28e3032804cbf853d
Autor:
Akihiro Inoue, Takanori Ohnishi, Masahiro Nishikawa, Hideaki Watanabe, Kosuke Kusakabe, Mashio Taniwaki, Hajime Yano, Yoshihiro Ohtsuka, Shirabe Matsumoto, Satoshi Suehiro, Daisuke Yamashita, Seiji Shigekawa, Hisaaki Takahashi, Riko Kitazawa, Junya Tanaka, Takeharu Kunieda
Publikováno v:
Biomedicines, Vol 11, Iss 9, p 2369 (2023)
Recurrent glioblastoma multiforme (GBM) is largely attributed to peritumoral infiltration of tumor cells. As higher CD44 expression in the tumor periphery correlates with higher risk of GBM invasion, the present study analyzed the relationship betwee
Externí odkaz:
https://doaj.org/article/44706f2a476847e3abcc2f9a4dfed5f5
Autor:
Saya Ozaki, Akihiro Umakoshi, Hajime Yano, Shota Ohsumi, Yutaro Sumida, Erika Hayase, Eika Usa, Afsana Islam, Mohammed E. Choudhury, Yusuke Nishi, Daisuke Yamashita, Yoshihiro Ohtsuka, Masahiro Nishikawa, Akihiro Inoue, Satoshi Suehiro, Jun Kuwabara, Hideaki Watanabe, Yasutsugu Takada, Yuji Watanabe, Ichiro Nakano, Takeharu Kunieda, Junya Tanaka
Publikováno v:
Neoplasia: An International Journal for Oncology Research, Vol 23, Iss 8, Pp 754-765 (2021)
The abilities to invade surrounding tissues and metastasize to distant organs are the most outstanding features that distinguish malignant from benign tumors. However, the mechanisms preventing the invasion and metastasis of benign tumor cells remain
Externí odkaz:
https://doaj.org/article/b56b30c37d804d6299ad8d65387f3147
Autor:
Shirabe Matsumoto, Mohammed E. Choudhury, Haruna Takeda, Arisa Sato, Nanako Kihara, Kanta Mikami, Akihiro Inoue, Hajime Yano, Hideaki Watanabe, Yoshiaki Kumon, Takeharu Kunieda, Junya Tanaka
Publikováno v:
Frontiers in Neuroscience, Vol 16 (2022)
Ischemic stroke is a leading cause of mortality and permanent disability. Chronic stroke lesions increase gradually due to the secondary neuroinflammation that occurs following acute ischemic neuronal degeneration. In this study, the ameliorating eff
Externí odkaz:
https://doaj.org/article/4ecd7bcc070346809c94f2c50fc1e634
Autor:
Masahiro Nishikawa, Akihiro Inoue, Takanori Ohnishi, Hajime Yano, Yonehiro Kanemura, Shohei Kohno, Shiro Ohue, Saya Ozaki, Shirabe Matsumoto, Satoshi Suehiro, Yawara Nakamura, Seiji Shigekawa, Hideaki Watanabe, Riko Kitazawa, Junya Tanaka, Takeharu Kunieda
Publikováno v:
Cancer Medicine, Vol 10, Iss 6, Pp 2013-2025 (2021)
Abstract Antiangiogenic therapy with bevacizumab (Bev), a monoclonal antibody targeting vascular endothelial growth factor (VEGF), is a common treatment for recurrent glioblastoma (GBM), but its survival benefit is limited. Resistance to Bev is thoug
Externí odkaz:
https://doaj.org/article/c9c9b0ba3246479ab1c5326b3e7cd505
Autor:
Hiroki Takeuchi, Mari Yamamoto, Megumi Fukui, Akihiro Inoue, Tadashi Maezawa, Mikiko Nishioka, Eiji Kondo, Tomoaki Ikeda, Kazuya Matsumoto, Kei Miyamoto
Publikováno v:
Reproductive Medicine and Biology, Vol 21, Iss 1, Pp n/a-n/a (2022)
Abstract Purpose In vitro maturation (IVM) of human oocytes offers an invaluable opportunity for infertility treatment. However, in vitro matured oocytes often show lower developmental abilities than their in vivo counterparts, and molecular mechanis
Externí odkaz:
https://doaj.org/article/6c17ed69beb34dbea0cdd8fbc91fcc79
Autor:
Shogo B. Kobayashi, Hirofumi Noda, Teruaki Enoto, Tomohisa Kawashima, Akihiro Inoue, Ken Ohsuga
Publikováno v:
The Astrophysical Journal, Vol 955, Iss 2, p 124 (2023)
A phase-resolved analysis on the X-ray spectrum of ultraluminous X-ray pulsar (ULXP) NGC 300 ULX-1 is performed with data taken with XMM-Newton and NuSTAR on 2016 December 16. In addition to the classical phase-restricting analysis, a method develope
Externí odkaz:
https://doaj.org/article/7c52aed408424204880e0fb5c415e905
Publikováno v:
The Astrophysical Journal, Vol 952, Iss 1, p 62 (2023)
We perform general relativistic radiation magnetohydrodynamics simulations of super-Eddington accretion flows around a neutron star with a dipole magnetic field for modeling the Galactic ultraluminous X-ray source exhibiting X-ray pulsations, Swift J
Externí odkaz:
https://doaj.org/article/b9ab56328902491c8e321ee910d1c602
Autor:
Masahiro Nishikawa, Akihiro Inoue, Takanori Ohnishi, Hajime Yano, Saya Ozaki, Yonehiro Kanemura, Satoshi Suehiro, Yoshihiro Ohtsuka, Shohei Kohno, Shiro Ohue, Seiji Shigekawa, Hideaki Watanabe, Riko Kitazawa, Junya Tanaka, Takeharu Kunieda
Publikováno v:
Translational Oncology, Vol 14, Iss 8, Pp 101137- (2021)
The poor prognosis of glioblastoma multiforme (GBM) is primarily due to highly invasive glioma stem-like cells (GSCs) in tumors. Upon GBM recurrence, GSCs with highly invasive and highly migratory activities must assume a less-motile state and prolif
Externí odkaz:
https://doaj.org/article/33c4ef903c5b4700aee894ff74b59436