Zobrazeno 1 - 10
of 185
pro vyhledávání: '"Akihiro IMAMURA"'
Autor:
Erik P. Lillehoj, Yafan Yu, Avelino C. Verceles, Akihiro Imamura, Hideharu Ishida, Kurt H. Piepenbrink, Simeon E. Goldblum
Publikováno v:
iScience, Vol 27, Iss 9, Pp 110866- (2024)
Summary: Stenotrophomonas maltophilia (Sm), a multidrug-resistant pathogen often isolated from immunocompromised individuals, presents its flagellin to multimeric tandem repeats within the ectodomain of mucin-1 (MUC1-ED), expressed on airway epitheli
Externí odkaz:
https://doaj.org/article/321142e490cf4f108f71724009877c4d
Autor:
Shogo Hamajima, Naoko Komura, Hide-Nori Tanaka, Akihiro Imamura, Hideharu Ishida, Tsuyoshi Ichiyanagi, Hiromune Ando
Publikováno v:
Molecules, Vol 28, Iss 1, p 102 (2022)
Chemical synthesis of 3-deoxy-d-manno-2-octulosonic acid (Kdo)-containing glycans, such as bacterial lipopolysaccharides (LPSs) and capsular polysaccharides (CPSs), is in high demand for the development of vaccines against pathogenic bacteria. We hav
Externí odkaz:
https://doaj.org/article/7dda1693ce254c84a610edfd9a38b88b
Autor:
Naoko Matsubara, Akihiro Imamura, Tatsuya Yonemizu, Chizuru Akatsu, Hongrui Yang, Akiharu Ueki, Natsuki Watanabe, Hajjaj Abdu-Allah, Nobutaka Numoto, Hiromu Takematsu, Shinobu Kitazume, Thomas F. Tedder, Jamey D. Marth, Nobutoshi Ito, Hiromune Ando, Hideharu Ishida, Makoto Kiso, Takeshi Tsubata
Publikováno v:
Frontiers in Immunology, Vol 9 (2018)
Sialic acid-binding immunoglobulin-like lectins (Siglecs) are expressed in various immune cells and most of them carry signaling functions. High-affinity synthetic sialoside ligands have been developed for various Siglecs. Therapeutic potentials of t
Externí odkaz:
https://doaj.org/article/b295e45b1a9243a2b75066dfbe524004
Autor:
Megumi Yamagishi, Ritsuko Hosoda-Yabe, Hideki Tamai, Miku Konishi, Akihiro Imamura, Hideharu Ishida, Tomio Yabe, Hiromune Ando, Makoto Kiso
Publikováno v:
Marine Drugs, Vol 13, Iss 12, Pp 7250-7274 (2015)
LLG-3 is a ganglioside isolated from the starfish Linchia laevigata. To clarify the structure-activity relationship of the glycan of LLG-3 toward rat pheochromocytoma PC12 cells in the presence of nerve growth factor, a series of mono- to tetrasaccha
Externí odkaz:
https://doaj.org/article/ce526e434542440dbd5f813448d8f009
Publikováno v:
Molecules, Vol 18, Iss 12, Pp 15153-15181 (2013)
The development of a novel cyclic glucosyl ceramide cassette acceptor for efficient glycolipid syntheses was investigated. p-Methoxybenzyl (PMB) groups were selected as protecting groups at C2 and C3 of the glucose residue with the aim of improving t
Externí odkaz:
https://doaj.org/article/18534c9f8fed467fb11e97dfc0e19e0d
Publikováno v:
Molecules, Vol 19, Iss 1, Pp 414-437 (2013)
A new chemical approach to synthesizing human ABO histo-blood type 2 antigenic determinants was developed. N-Phthaloyl-protected lactosaminyl thioglycoside derived from lactulose via the Heyns rearrangement was employed to obtain a type 2 core disacc
Externí odkaz:
https://doaj.org/article/bbe3d263edeb4e7885a264e27c51195f
Autor:
Tomohiro Nohara, Akihiro Imamura, Maho Yamaguchi, Kazuya I. P. J. Hidari, Takashi Suzuki, Tatsuya Komori, Hiromune Ando, Hideharu Ishida, Makoto Kiso
Publikováno v:
Molecules, Vol 17, Iss 8, Pp 9590-9620 (2012)
A novel ganglioside bearing Neua2-3Gal and Neua2-6Gal structures as distal sequences was designed as a ligand for influenza A viruses. The efficient synthesis of the designed ganglioside was accomplished by employing the cassette coupling approach as
Externí odkaz:
https://doaj.org/article/fe118eba9e694e7d8777254dec51ef88
Autor:
Daisuke Kobayashi, Akiharu Ueki, Tomoya Yamaji, Kazuya Nagao, Akihiro Imamura, Hiromune Ando, Makoto Kiso, Hideharu Ishida
Publikováno v:
Molecules, Vol 21, Iss 5, p 614 (2016)
The convergent synthesis of the Lewis A (Lea) tandem repeat is described. The Lea tandem repeat is a carbohydrate ligand for a mannose binding protein that shows potent inhibitory activity against carcinoma growth. The Lea unit, {β-d-Gal-(1→3)-[α
Externí odkaz:
https://doaj.org/article/cb3c21e701c54d23ac59569568447a0d
Autor:
Ursula Neu, Holger Hengel, Bärbel S Blaum, Rachel M Schowalter, Dennis Macejak, Michel Gilbert, Warren W Wakarchuk, Akihiro Imamura, Hiromune Ando, Makoto Kiso, Niklas Arnberg, Robert L Garcea, Thomas Peters, Christopher B Buck, Thilo Stehle
Publikováno v:
PLoS Pathogens, Vol 8, Iss 7, p e1002738 (2012)
The recently discovered human Merkel cell polyomavirus (MCPyV or MCV) causes the aggressive Merkel cell carcinoma (MCC) in the skin of immunocompromised individuals. Conflicting reports suggest that cellular glycans containing sialic acid (Neu5Ac) ma
Externí odkaz:
https://doaj.org/article/e1a4070320af41d0a03d18a140ddc822
Publikováno v:
PLoS Pathogens, Vol 4, Iss 8, p e1000129 (2008)
Botulinum neurotoxins have a very high affinity and specificity for their target cells requiring two different co-receptors located on the neuronal cell surface. Different toxin serotypes have different protein receptors; yet, most share a common gan
Externí odkaz:
https://doaj.org/article/cc26cd65e05f464fa41c8b2d574914c4