Zobrazeno 1 - 10
of 161
pro vyhledávání: '"Akihiro, Tsuboi"'
Autor:
Hikaru Minagawa, Yoshiko Hashii, Hiroko Nakajima, Fumihiro Fujiki, Soyoko Morimoto, Jun Nakata, Toshiro Shirakawa, Takane Katayama, Akihiro Tsuboi, Keiichi Ozono
Publikováno v:
BMC Cancer, Vol 23, Iss 1, Pp 1-11 (2023)
Abstract Background A Wilms’ tumor 1 (WT1) oral vaccine, Bifidobacterium longum (B. longum) 420, in which the bacterium is used as a vector for WT1 protein, triggers immune responses through cellular immunity consisting of cytotoxic T lymphocytes (
Externí odkaz:
https://doaj.org/article/530ac44263ef437fa04cd0dcba8fa563
Autor:
Fumihiro Fujiki, Soyoko Morimoto, Akiko Katsuhara, Akane Okuda, Saeka Ogawa, Eriko Ueda, Maki Miyazaki, Ayako Isotani, Masahito Ikawa, Sumiyuki Nishida, Hiroko Nakajima, Akihiro Tsuboi, Yoshihiro Oka, Jun Nakata, Naoki Hosen, Atsushi Kumanogoh, Yusuke Oji, Haruo Sugiyama
Publikováno v:
Frontiers in Immunology, Vol 13 (2022)
Memory T cells play an essential role in infectious and tumor immunity. Vitamin A metabolites such as retinoic acid are immune modulators, but the role of vitamin A metabolism in memory T-cell differentiation is unclear. In this study, we identified
Externí odkaz:
https://doaj.org/article/be408ef12699491a8d81c30d652284b0
Autor:
Yoshiko Hashii, Yoshihiro Oka, Naoki Kagawa, Naoya Hashimoto, Hiroyuki Saitou, Syogo Fukuya, Mizuki Kanegae, Sayaka Ikejima, Yusuke Oji, Keiichi Ozono, Akihiro Tsuboi, Haruo Sugiyama
Publikováno v:
Frontiers in Oncology, Vol 10 (2020)
Diffuse midline glioma (DMG) in children is a highly aggressive, malignant brain tumor that is fatal when relapsed. Wilms tumor 1 (WT1) is a high-priority antigen target for cancer immunotherapy. We hereby report on a pediatric patient who had DMG th
Externí odkaz:
https://doaj.org/article/1d662f20d7d34a838619aa5f8de91774
Autor:
Jun Nakata, Kayako Isohashi, Yoshihiro Oka, Hiroko Nakajima, Soyoko Morimoto, Fumihiro Fujiki, Yusuke Oji, Akihiro Tsuboi, Atsushi Kumanogoh, Naoya Hashimoto, Jun Hatazawa, Haruo Sugiyama
Publikováno v:
Diagnostics, Vol 11, Iss 6, p 1041 (2021)
Assessment of tumor response during treatment is one of the most important purposes of imaging. Before the appearance of immunotherapy, response evaluation criteria in solid tumors (RECIST) and positron emission tomography response criteria in solid
Externí odkaz:
https://doaj.org/article/a4175109914048c59d1b9fef5e02ee8a
Autor:
Natsuki Nakagawa, Yoshiko Hashii, Hisako Kayama, Ryu Okumura, Hiroko Nakajima, Hikaru Minagawa, Soyoko Morimoto, Fumihiro Fujiki, Jun Nakata, Toshiro Shirakawa, Takane Katayama, Kiyoshi Takeda, Akihiro Tsuboi, Keiichi Ozono
Publikováno v:
Cancer Immunology, Immunotherapy. 72:39-53
Wilms’ tumor 1 (WT1) is a promising tumor-associated antigen for cancer immunotherapy. We developed an oral protein vaccine platform composed of WT1-anchored, genetically engineered Bifidobacterium longum (B. longum) and conducted an in vivo study
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::48b62b2f682184424c4cdfae1acae8f1
https://doi.org/10.1007/s00262-022-03214-4
https://doi.org/10.1007/s00262-022-03214-4
Autor:
Fumihiro Fujiki, Soyoko Morimoto, Yuya Nishida, Satoe Tanii, Nao Aoyama, Miki Inatome, Kento Inoue, Akiko Katsuhara, Hiroko Nakajima, Jun Nakata, Sumiyuki Nishida, Akihiro Tsuboi, Yoshihiro Oka, Yusuke Oji, Shinji Sogo, Haruo Sugiyama
Publikováno v:
Cancer Immunology, Immunotherapy.
CD4+ T cells that recognize antigenic peptides presented on HLA class II are essential for inducing an optimal anti-tumor immune response, and adoptive transfer of tumor antigen-specific TCR-transduced CD4+ T cells with high responsiveness against tu
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::23d779525c9dfd7cc9d1e7ec93514433
https://doi.org/10.1007/s00262-023-03420-8
https://doi.org/10.1007/s00262-023-03420-8
Autor:
Akihiro Tsuboi, Haruo Sugiyama, Shinji Sogo, Naoki Hosen, Kanako Imafuku, Kana Hasegawa, Sumiyuki Nishida, Soyoko Morimoto, Keiko Udaka, Kazuki Isokawa, Fumihiro Fujiki, Jun Nakata, Yusuke Oji, Hiroko Nakajima, Yoshiko Hashii, Hiromu Hayashibara, Yoshihiro Oka
Publikováno v:
Cancer Immunology, Immunotherapy. 70:3323-3335
Helper T lymphocytes (HTLs) play a central role in cancer immunity because they can not only help the induction and proliferation of cytotoxic T lymphocytes (CTLs) but also their differentiation into cytotoxic CD4+ T cells and directly kill the targe
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::54612aeda12e13a368231ccfd79f9115
https://doi.org/10.1007/s00262-021-03003-5
https://doi.org/10.1007/s00262-021-03003-5
Autor:
Akane Okuda, Maki Miyazaki, Naoki Hosen, Soyoko Morimoto, Haruo Sugiyama, Saeka Ogawa, Atsushi Kumanogoh, Yusuke Oji, Akihiro Tsuboi, Hiroko Nakajima, Eriko Ueda, Ayako Isotani, Akiko Katsuhara, Jun Nakata, Yoshihiro Oka, Fumihiro Fujiki, Masahito Ikawa, Sumiyuki Nishida
Publikováno v:
Frontiers in immunology. 13
Memory T cells play an essential role in infectious and tumor immunity. Vitamin A metabolites such as retinoic acid are immune modulators, but the role of vitamin A metabolism in memory T- cell differentiation is unclear. In this study, we identified
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::81df43e3d0261ebc9f7c8bf5f4fe63eb
https://pubmed.ncbi.nlm.nih.gov/35844620
https://pubmed.ncbi.nlm.nih.gov/35844620
Autor:
Kana Hasegawa, Satomi Tanaka, Fumihiro Fujiki, Soyoko Morimoto, Katsuhiko Nakano, Hiroko Kinoshita, Atsushi Okumura, Yuka Fujioka, Rika Urakawa, Hiroko Nakajima, Naoya Tatsumi, Jun Nakata, Satoshi Takashima, Sumiyuki Nishida, Akihiro Tsuboi, Yoshihiro Oka, Yusuke Oji, Eiji Miyoshi, Takako Hirata, Atsushi Kumanogoh, Haruo Sugiyama, Naoki Hosen
Publikováno v:
PLoS ONE, Vol 11, Iss 3, p e0152326 (2016)
To improve cancer immunotherapy, it is important to understand how tumor cells counteract immune-surveillance. In this study, we sought to identify cell-surface molecules associated with resistance of leukemia cells to cytotoxic T cell (CTL)-mediated
Externí odkaz:
https://doaj.org/article/94c069a8b32e45ffa55603171c95423f
Autor:
Naoya Hashimoto, Kana Hasegawa, Shinji Sogo, Haruo Sugiyama, Yoshihiro Oka, Yusuke Oji, Naoki Hosen, Fumihiro Fujiki, Jun Nakata, Soyoko Morimoto, Akihiro Tsuboi, Hiroko Nakajima, Sumiyuki Nishida, Miki Inatome
Publikováno v:
Cancer Immunology, Immunotherapy. 70:253-263
Simultaneous induction of tumor antigen-specific cytotoxic T lymphocytes (CTLs) and helper T lymphocytes (HTLs) is required for an optimal anti-tumor immune response. WT1332, a 16-mer WT1-derived helper peptide, induce HTLs in an HLA class II-restric
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::6ee133ee71b13085a1901d4ad1c89107
https://doi.org/10.1007/s00262-020-02675-9
https://doi.org/10.1007/s00262-020-02675-9