Basigin deficiency prevents anaplerosis and ameliorates insulin resistance and hepatosteatosis

Autor: Akihiro Ryuge, Tomoki Kosugi, Kayaho Maeda, Ryoichi Banno, Yang Gou, Kei Zaitsu, Takanori Ito, Yuka Sato, Akiyoshi Hirayama, Shoma Tsubota, Takashi Honda, Kazuki Nakajima, Tomoya Ozaki, Kunio Kondoh, Kazuo Takahashi, Noritoshi Kato, Takuji Ishimoto, Tomoyoshi Soga, Takahiko Nakagawa, Teruhiko Koike, Hiroshi Arima, Yukio Yuzawa, Yasuhiko Minokoshi, Shoichi Maruyama, Kenji Kadomatsu

Publikováno v: JCI Insight, Vol 6, Iss 20 (2021)

Monocarboxylates, such as lactate and pyruvate, are precursors for biosynthetic pathways, including those for glucose, lipids, and amino acids via the tricarboxylic acid (TCA) cycle and adjacent metabolic networks. The transportation of monocarboxyla

Externí odkaz: https://doaj.org/article/2d5d18e46a2a402ab5dd1a6ba411562d

CD147 Is Essential for the Development of Psoriasis via the Induction of Th17 Cell Differentiation

Autor: Aoi Okubo, Youhei Uchida, Yuko Higashi, Takuya Sato, Youichi Ogawa, Akihiro Ryuge, Kenji Kadomatsu, Takuro Kanekura

Publikováno v: International Journal of Molecular Sciences, Vol 23, Iss 177, p 177 (2022)
International Journal of Molecular Sciences; Volume 23; Issue 1; Pages: 177
International Journal of Molecular Sciences

Th17 cells play an important role in psoriasis. The differentiation of naïve CD4+ T cells into Th17 cells depends on glycolysis as the energy source. CD147/basigin, an integral transmembrane protein belonging to the immunoglobulin superfamily, regul

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::824b6742f79b767d0c419bb863825568
https://www.mdpi.com/1422-0067/23/1/177

Refractory Hypotension Caused by Selenium Deficiency in a Patient on Peritoneal Dialysis

Autor: Masashi Mizuno, Hangsoo Kim, Shoji Saito, Yasuhiro Suzuki, Akihiro Ryuge, Shoichi Maruyama, Noritoshi Kato, Masaki Okazaki, Takuji Ishimoto, Hiroshi Kojima, Tomoki Kosugi

Publikováno v: Internal Medicine

Selenium is essential for human health; its deficiency leads to cardiac dysfunction. We herein report a 79-year-old man on peritoneal dialysis who presented with refractory hypotension caused by selenium deficiency. He was admitted to our hospital wi

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::459382770e0bf00a3bcdd38021666e2c
http://europepmc.org/articles/PMC8381165

Calcium pyrophosphate deposition disease involving 'the largest' Bursa in the human body

Autor: Yoshiro Fujita, Naoho Takizawa, Akihiro Ryuge, Hideaki Shimizu, Atsushi Nomura, Masahiko Yazawa, Yoichiro Haji, Yukako Ohyama

Publikováno v: Journal of nephrology. 35(2)

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::921db537d49f1d5269970049627ceee1
https://pubmed.ncbi.nlm.nih.gov/34057674

examination of the effects of liraglutide on diabetic nephropathy

Autor: Akihiro Ryuge, Kusama Minoru, Kouchi Yu, Ozeki Takaya, Yazawa Masahiko, Yamaguchi Makoto, Ohyama Yukako, Haji Yoichiro, Imaizumi Takahiro, Tomino Tatsuhito, Shimizu Hideaki, Nakashima Eitaro, Fujita Yoshiro

Publikováno v: Kidney Research and Clinical Practice, Vol 31, Iss 2, p A70 (2012)

Liraglutide (Lira), a glucagon-like peptide-1 receptor agonist, can be administered to diabetic patients with renal failure without dose reduction, but experience with the use of Lira in these patients is limited. This study was designed to examine t

Externí odkaz: https://doaj.org/article/8410334723e24f49af3d4f9e360e6b23