Zobrazeno 1 - 10
of 218
pro vyhledávání: '"Akihiko Taguchi"'
E4BP4 in macrophages induces an anti-inflammatory phenotype that ameliorates the severity of colitis
Autor:
Yasuko Kajimura, Akihiko Taguchi, Yuko Nagao, Kaoru Yamamoto, Konosuke Masuda, Kensuke Shibata, Yoichi Asaoka, Makoto Furutani-Seiki, Yukio Tanizawa, Yasuharu Ohta
Publikováno v:
Communications Biology, Vol 7, Iss 1, Pp 1-13 (2024)
Abstract Macrophages are versatile cells of the innate immune system that work by altering their pro- or anti-inflammatory features. Their dysregulation leads to inflammatory disorders such as inflammatory bowel disease. We show that macrophage-speci
Externí odkaz:
https://doaj.org/article/879803a9b0d84608b6eb34f41f5360eb
Autor:
Kazuta Yasui, Yuko Ogawa, Orie Saino, Rie Akamatsu, Akihiro Fuchizaki, Yoriko Irie, Makoto Nabetani, Mitsunobu Tanaka, Yoshihiro Takihara, Akihiko Taguchi, Takafumi Kimura
Publikováno v:
Scientific Reports, Vol 14, Iss 1, Pp 1-14 (2024)
Abstract Although regenerative therapy with stem cells is believed to be affected by their proliferation and differentiation potential, there is insufficient evidence regarding the molecular and cellular mechanisms underlying this regenerative effect
Externí odkaz:
https://doaj.org/article/af37cbcf8f50440eb72beebeee0cfdf9
Autor:
Ryoko Hatanaka, Akihiko Taguchi, Yuko Nagao, Kaito Yorimoto, Akari Takesato, Konosuke Masuda, Takao Ono, Yoshishige Samukawa, Yukio Tanizawa, Yasuharu Ohta
Publikováno v:
Heliyon, Vol 10, Iss 16, Pp e35978- (2024)
Sudachitin, a member of the flavonoid family, reportedly improves glucose metabolism after long-term administration, but details of the underlying mechanisms are unknown. We found that Sudachitin approximately doubles insulin secretion under high glu
Externí odkaz:
https://doaj.org/article/0afeab4bfa374e88974e359860586d45
Autor:
Ruriko Fujimoto, Ysuharu Ohta, Konosuke Masuda, Akihiko Taguchi, Masaru Akiyama, Kaoru Yamamoto, Hiroko Nakabayashi, Yuko Nagao, Takuro Matsumura, Syunsuke Hiroshige, Yasuko Kajimura, Makoto Akashi, Yukio Tanizawa
Publikováno v:
Journal of Diabetes Investigation, Vol 13, Iss 9, Pp 1496-1505 (2022)
Abstract Aims/Introduction Understanding morning–evening variation in metabolic state is critical for managing metabolic disorders. We aimed to characterize this variation from the viewpoints of insulin secretion and insulin sensitivity, including
Externí odkaz:
https://doaj.org/article/beb03a85e06c4f5486ed371cc7ca4bc2
Publikováno v:
Cell Transplantation, Vol 32 (2023)
Autism spectrum disorder (ASD) is a complex neurodevelopmental disorder characterized by difficulties in social communication, repetitive behaviors, and restricted interests, with onset early in life. The prevalence of ASD has increased worldwide in
Externí odkaz:
https://doaj.org/article/42769ac663f048acbca09e1d0efbc552
Autor:
Yuko Ogawa, Rie Akamatsu, Akihiro Fuchizaki, Kazuta Yasui, Orie Saino, Mitsunobu Tanaka, Akie Kikuchi-Taura, Takafumi Kimura, Akihiko Taguchi
Publikováno v:
Cell Transplantation, Vol 31 (2022)
We have previously demonstrated that small molecular transfer, such as glucose, between hematopoietic stem cells (HSCs) or mesenchymal stem cells (MSCs) and vascular endothelial cells via gap junctions constitutes an important mechanism of stem cell
Externí odkaz:
https://doaj.org/article/616031fe4aaf4aa8b5178e4811abe088
Autor:
Yuko Ogawa, Yuka Okinaka, Akie Kikuchi-Taura, Orie Saino, Ayumi Tani-Yokoyama, Satoru Masuda, Miki Komatsu-Horii, Yoshihiko Ikemoto, Atsuhiko Kawamoto, Masanori Fukushima, Akihiko Taguchi
Publikováno v:
Frontiers in Medicine, Vol 9 (2022)
This study was conducted to evaluate the safety and efficacy of human peripheral blood CD34 positive (CD34+) cells transplanted into a murine chronic stroke model to obtain pre-clinical proof of concept, prior to clinical testing. Granulocyte colony
Externí odkaz:
https://doaj.org/article/2d937bb7b7eb4906b9ea8701e52ba131
Publikováno v:
International Journal of Molecular Sciences, Vol 24, Iss 2, p 1774 (2023)
Microglial cells (MGs), originally derived from progenitor cells in a yolk sac during early development, are glial cells located in a physiological and pathological brain. Since the brain contains various cell types, MGs could frequently interact wit
Externí odkaz:
https://doaj.org/article/3fb48c4a08c14a61badd0ca6ec260d70
Autor:
Yukiko Takeuchi, Orie Saino, Yuka Okinaka, Yuko Ogawa, Rie Akamatsu, Akie Kikuchi-Taura, Yosky Kataoka, Mitsuyo Maeda, Sheraz Gul, Carsten Claussen, Johannes Boltze, Akihiko Taguchi
Publikováno v:
Frontiers in Aging Neuroscience, Vol 14 (2022)
Circulating white blood cells (WBC) contribute toward maintenance of cerebral metabolism and brain function. Recently, we showed that during aging, transcription of metabolism related genes, including energy source transports, in the brain significan
Externí odkaz:
https://doaj.org/article/1b2dedb6992a4ec2813b5cc2b7637eb2
Autor:
Biliana Marcheva, Benjamin J Weidemann, Akihiko Taguchi, Mark Perelis, Kathryn Moynihan Ramsey, Marsha V Newman, Yumiko Kobayashi, Chiaki Omura, Jocelyn E Manning Fox, Haopeng Lin, Patrick E Macdonald, Joseph Bass
Publikováno v:
eLife, Vol 11 (2022)
The mammalian circadian clock drives daily oscillations in physiology and behavior through an autoregulatory transcription feedback loop present in central and peripheral cells. Ablation of the core clock within the endocrine pancreas of adult animal
Externí odkaz:
https://doaj.org/article/4ba877e38361469da7c8d4a16351a710