Zobrazeno 1 - 10
of 133
pro vyhledávání: '"Akihiko Maekawa"'
Publikováno v:
Journal of Toxicologic Pathology
Involvements of estrogen receptor (ER)α, proliferating cell nuclear antigen (PCNA) and p53 in the uterine carcinogenesis process in Donryu rats, a high yield strain of the uterine cancer were investigated immunohistochemically. ERα was expressed in
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a554fb6a7867956b31780fd4d96e4b8a
http://europepmc.org/articles/PMC3517919
http://europepmc.org/articles/PMC3517919
Autor:
Makoto Hayashi, Akihiko Maekawa, Toshio Imai, Midori Yoshida, Tatsuhiro Yamashita, Yuki Sakuratani, Jun Yamada, Satoshi Nishikawa
Publikováno v:
The Journal of Toxicological Sciences. 35:E1-E8
Because histopathological findings are often conclusive indicators of the toxicities of chemicals, standardization of nomenclature and construction of a thesaurus for histopathological findings are important for the comparative evaluation of histopat
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b2bf1860076766c04f1b1ae1f2c2f796
https://doi.org/10.2131/jts.35.e1
https://doi.org/10.2131/jts.35.e1
Autor:
Satoshi, Nishikawa, Tatsuhiro, Yamashita, Toshio, Imai, Midori, Yoshida, Yuki, Sakuratani, Jun, Yamada, Akihiko, Maekawa, Makoto, Hayashi
Publikováno v:
The Journal of Toxicological Sciences. 35:295-298
Because histopathological findings are often conclusive indicators of the toxicities of chemicals, standardization of nomenclature and construction of a thesaurus for histopathological findings are important for the comparative evaluation of histopat
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e153c77f5fad70af1a18aeb343f107f5
https://doi.org/10.2131/jts.35.295
https://doi.org/10.2131/jts.35.295
Autor:
Manabu Watanabe, Nozomi Miyajima, Tsuneyuki Oikawa, Yoshifumi Endo, Sumio Sugano, Maki Igarashi, Akihiko Maekawa, Takuya Sakurai, Toshiyuki Yamada, Dai Nakae, Midori Yoshida
Publikováno v:
Lung. 185:271-278
In this study we investigated the Ser33 phosphorylation status of beta-catenin protein in relation to genomic mutations in lung (pre)neoplastic lesions induced by N-nitrosobis(2-hydroxypropyl)amine (BHP) in male Fischer 344 rats. Six-week-old animals
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::50679abdbb7c690ab9174d5a045bfd19
https://doi.org/10.1007/s00408-007-9017-y
https://doi.org/10.1007/s00408-007-9017-y
The leukemogenic effect of 1-propyl- and 1-butyl-1-nitrosourea (PNU and BNU) was studied in Donryu and Sprague-Dawley rats, which received the chemical in their drinking water. BNU produced leukemia in 42 out of 46 (91%) of the Donryu rats, and the m
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::4a5a274387a865e27e4e68549c7c11d2
https://doi.org/10.1159/000397525
https://doi.org/10.1159/000397525
Autor:
Tadaichi Kitamura, Dai Nakae, Yoshinori Murakami, Shinji Kikuchi, Daisuke Yamada, Mari Masuda, Tsutomu Ohta, Takeshi Fukami, Tomoko Maruyama, Akihiko Maekawa, Midori Yoshida, Yuko N. Williams
Publikováno v:
Molecular and Cellular Biology. 26:3610-3624
TSLC1/IGSF4, an immunoglobulin superfamily molecule, is predominantly expressed in the brain, lungs, and testes and plays important roles in epithelial cell adhesion, cancer invasion, and synapse formation. We generated Tslc1/Igsf4-deficient mice by
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::0e9e620dcc5170c4b64139958a46f9b0
https://doi.org/10.1128/mcb.26.9.3610-3624.2006
https://doi.org/10.1128/mcb.26.9.3610-3624.2006
Autor:
Akihiko Maekawa, Koji Usuda, Noriko Suzuki, Tsutomu Okubo, Lekh Raj Juneja, Dai Nakae, Midori Yoshida, Maki Igarashi, Satoshi Furukawa, Masayoshi Abe
Publikováno v:
Journal of Toxicologic Pathology. 19:129-135
The present study was conducted as a preliminary evaluation of toxicologic and carcinogenic risks of copper gluconate and to determine its optimal dose for use in an upcoming study utilizing the medium-term multi-organ carcinogenesis protocol. Male B
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::9350c9154e1922ca0a8e9a2b166d734b
https://doi.org/10.1293/tox.19.129
https://doi.org/10.1293/tox.19.129
Autor:
Mayumi Nishimura, Ayako Teramoto, Shizuko Kakinuma, Tatsuhiko Imaoka, Akihiko Maekawa, Masami Ootawara, Harumi Osada, Yukiko Nishimura, Yoshiya Shimada
Publikováno v:
International Journal of Cancer. 115:187-193
Humans are continually exposed to various environmental carcinogens. Cancers may arise as a result of exposure to carcinogenic chemicals, ionizing radiation or a combination thereof. However, the mechanism of combined carcinogenesis has been only ded
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::dd55914d5e2e6ab6e0ce37e4573b7c3f
https://doi.org/10.1002/ijc.20904
https://doi.org/10.1002/ijc.20904
Autor:
Midori Yoshida, Dai Nakae, Fumiyuki Uematsu, Yoichi Konishi, Masakazu Takahashi, Yutaka Hatanaka, Akihiko Maekawa
Publikováno v:
Toxicologic Pathology. 33:185-203
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::944f85a58d7ce234fa7ff4da9f568405
https://doi.org/10.1080/01926230590881899
https://doi.org/10.1080/01926230590881899
Autor:
Shin-ichi Katsuda, Takasumi Shimomoto, Dai Nakae, Fumiyuki Uematsu, Masakazu Takahashi, Hiroki Kuniyasu, Akihiko Maekawa, Midori Yoshida
Publikováno v:
Journal of Toxicologic Pathology. 18:47-52
In human endometrium, α-smooth muscle actin (α-SMA)-positive stromal cells (SMA-SCs) surround endometrial glands, and the α-SMA expression is regulated by estrogen. The biological significance of these cells remains to be elucidated, and no inform
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::504a526efb3622279bea34581feafd98
https://doi.org/10.1293/tox.18.47
https://doi.org/10.1293/tox.18.47