Zobrazeno 1 - 10
of 25
pro vyhledávání: '"Akihiko Kubota"'
Autor:
Ruoshui Li, Bijun Chen, Akihiko Kubota, Anis Hanna, Claudio Humeres, Silvia C. Hernandez, Yang Liu, Richard Ma, Izabela Tuleta, Shuaibo Huang, Harikrishnan Venugopal, Fenglan Zhu, Kai Su, Jun Li, Jinghang Zhang, Deyou Zheng, Nikolaos G. Frangogiannis
Publikováno v:
Nature Communications, Vol 14, Iss 1, Pp 1-21 (2023)
Abstract Macrophages sense changes in the extracellular matrix environment through the integrins and play a central role in regulation of the reparative response after myocardial infarction. Here we show that macrophage integrin α5 protects the infa
Externí odkaz:
https://doaj.org/article/2c80b06b17ca43dea72a0bd195b86518
Publikováno v:
Scientific Reports, Vol 12, Iss 1, Pp 1-17 (2022)
Abstract Reliable tools for macrophage identification in mouse tissues are critical for studies investigating inflammatory and reparative responses. Transgenic reporter mice and anti-macrophage antibodies have been used as “specific pan-macrophage
Externí odkaz:
https://doaj.org/article/3b7ea66225014cfbbd3e63a02dbf7432
Autor:
Akihiko Kubota, Nikolaos Frangogiannis
Publikováno v:
American journal of physiology. Cell physiology. 323(4)
The heart contains a population of resident macrophages that markedly expands following injury through recruitment of monocytes and through proliferation of macrophages. In myocardial infarction, macrophages have been implicated in both injurious and
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::20d7e01ab88b0d664e6886280b265400
https://pubmed.ncbi.nlm.nih.gov/36094436
https://pubmed.ncbi.nlm.nih.gov/36094436
Publikováno v:
Scientific reports. 12(1)
Reliable tools for macrophage identification in mouse tissues are critical for studies investigating inflammatory and reparative responses. Transgenic reporter mice and anti-macrophage antibodies have been used as “specific pan-macrophage” marker
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::0b4b9863e03042e7ef4cd3dd313db566
https://pubmed.ncbi.nlm.nih.gov/35296717
https://pubmed.ncbi.nlm.nih.gov/35296717
Publikováno v:
Journal of Molecular and Cellular Cardiology. 131:41-52
Background Various immune cells are involved in different phases of cardiac repair after myocardial infarction (MI). Especially, Ly6Clow M2-like macrophages (Ly6Clo macrophages) are vital for cardiac repair after MI. However, the molecular mechanisms
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::96a4fe39c9bc2ea94340c471a419e61d
https://doi.org/10.1016/j.yjmcc.2019.04.007
https://doi.org/10.1016/j.yjmcc.2019.04.007
Publikováno v:
American Journal of Physiology: Cell Physiology; Oct2022, Vol. 323 Issue 4, pC1304-C1324, 21p
Autor:
Yoshio Kobayashi, Akihiko Kubota, Issei Komuro, Hiroyuki Takano, Tomoko Yamada-Inagawa, Hiroyuki Tadokoro, Hiroshi Hasegawa, Haixiu Wang, Yuka Kobara, Masanori Hirose
Publikováno v:
Journal of Molecular and Cellular Cardiology. 91:72-80
Aims Dipeptidyl peptidase-4 (DPP-4) inhibitors are reported to have protective effects on various cells but it is unclear how DPP-4 inhibitors have cardioprotective effects. Our aim was to study the mechanisms of cardioprotective effects by DPP-4 inh
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::9c31f1a7a2b055701a0a209c31e63dd3
https://doi.org/10.1016/j.yjmcc.2015.12.026
https://doi.org/10.1016/j.yjmcc.2015.12.026
Publikováno v:
Journal of molecular and cellular cardiology. 131
Various immune cells are involved in different phases of cardiac repair after myocardial infarction (MI). Especially, Ly6CTranscriptome analysis of Ly6CMMP-12 produced by Ly6C
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::140b8af44d1e7aac040cacd5d3273609
https://pubmed.ncbi.nlm.nih.gov/31009606
https://pubmed.ncbi.nlm.nih.gov/31009606
Autor:
Yuka Kobara, Hiroshi Hasegawa, Tomoko Yamada-Inagawa, Akihiko Kubota, Yoshio Kobayashi, Masanori Hirose, Hiroyuki Tadokoro, Genzou Takemura, Hiroyuki Takano
Publikováno v:
Circulation journal : official journal of the Japanese Circulation Society. 80(9)
Background Inflammatory responses, especially by CD4(+)T cells activated by dendritic cells, are known to be important in the pathophysiology of cardiac repair after myocardial infarction (MI). Although co-stimulatory signals through B7 (CD80/86) and
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c1590af89d497dc29de682088f45a4d9
https://pubmed.ncbi.nlm.nih.gov/27396441
https://pubmed.ncbi.nlm.nih.gov/27396441
Autor:
Issei Komuro, Hiroyuki Tadokoro, Hiroyuki Takano, Akihiko Kubota, Hiroshi Hasegawa, Yoshio Kobayashi, Yoshihito Kameda
Publikováno v:
Circulation Journal. 76:1159-1168
Background: 3-Hydroxy-3-methylglutaryl coenzyme A reductase inhibitors (statins), which are widely used to lower plasma cholesterol levels, have been reported to have various pleiotropic effects such as protective effect of endothelial cells, angioge
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::698ba2065f8eb641834e2c6e1eda9a9d
https://doi.org/10.1253/circj.cj-11-1114
https://doi.org/10.1253/circj.cj-11-1114