Zobrazeno 1 - 10
of 117
pro vyhledávání: '"Akihiko Kameyama"'
Autor:
Takanori Sugiura, Kazuhiko Hashimoto, Kazutaka Kikuta, Ukei Anazawa, Takeshi Nomura, Akihiko Kameyama
Publikováno v:
Scientific Reports, Vol 13, Iss 1, Pp 1-9 (2023)
Abstract Mucoepidermoid carcinoma (MEC) is the most frequent of the rare salivary gland malignancies. We previously reported high expression of Mucin 1 (MUC1) modified with sialylated core-2 O-glycans in MEC by using tissue homogenates. In this study
Externí odkaz:
https://doaj.org/article/34a4279b5ebe4beaac14d2b4c09102af
Publikováno v:
PLoS ONE, Vol 16, Iss 1, p e0245607 (2021)
Mucins, the major components of salivary mucus, are large glycoproteins abundantly modified with O-glycans. Mucins present on the surface of oral tissues contribute greatly to the maintenance of oral hygiene by selectively adhering to the surfaces of
Externí odkaz:
https://doaj.org/article/6ede6f82ed7e404591e5554e554817ff
Publikováno v:
PLoS ONE, Vol 13, Iss 5, p e0196800 (2018)
Glycan analysis may result in exploitation of glycan biomarkers and evaluation of heterogeneity of glycosylation of biopharmaceuticals. For N-linked glycan analysis, we investigated alkaline hydrolysis of the asparagine glycosyl carboxamide of glycop
Externí odkaz:
https://doaj.org/article/4d18b07a41f240fea49c0c80e7b8afee
Autor:
Eisaku Isaka, Takanori Sugiura, Kazuhiko Hashimoto, Kazutaka Kikuta, Ukei Anazawa, Takeshi Nomura, Akihiko Kameyama
Publikováno v:
Electrophoresis Letters. 66:67-70
Publikováno v:
Applied Microbiology and Biotechnology. 104:8761-8773
Aspergillus oryzae produces glycoside hydrolases to degrade xyloglucan. We identified and characterized two xyloglucan-specific endo-1,4-glucanases (xyloglucanases) named Xeg12A and Xeg5A. Based on their amino acid sequences, Xeg12A and Xeg5A were cl
Autor:
Wenzhe Li, Weijie Dong, Akihiko Kameyama, Guoling Huang, Jianguo Gu, Gang Liu, Zhi Li, Shijie Sun, Yuqing Li
Publikováno v:
Biochemical Journal. 477:1179-1201
Fucosyltransferase 8 (FUT8) and β-galactoside α-2,6-sialyltransferase 1 (ST6GAL1) are glycosyltransferases that catalyze α1,6-fucosylation and α2,6-sialylation, respectively, in the mammalian N-glycosylation pathway. They are aberrantly expressed
Autor:
Tomohiko Matsuzawa, Masahiro Watanabe, Yusuke Nakamichi, Akihiko Kameyama, Naoshi Kojima, Katsuro Yaoi
Publikováno v:
Applied microbiology and biotechnologyReferences. 106(2)
α-Xylosidases release the α-D-xylopyranosyl side chain from di- and oligosaccharides derived from xyloglucans and are involved in xyloglucan degradation. In this study, an extracellular α-xylosidase, named AxyB, is identified and characterized in
Autor:
Takeshi Nomura, Ukei Anazawa, Takanori Sugiura, Eisaku Isaka, Kazutaka Kikuta, Kazuhiko Hashimoto, Akihiko Kameyama
Publikováno v:
Oncology Letters
Mucoepidermoid carcinoma (MEC) is one of the most frequently misdiagnosed tumors. Glycans are modulated by malignant transformation. Mucin 1 (MUC1) is a mucin whose expression is upregulated in various tumors, including MEC, and it has previously bee
Publikováno v:
The FEBS Journal. 286:3182-3193
The galactosylation of xyloglucan blocks many of the enzymatic processes targeting this oligosaccharide. We found that the expression of a gene encoding Aspergillus oryzae β-galactosidase (LacA) is induced in the presence of xyloglucan oligosacchari
Autor:
Lei Shi, Tonghui Ma, Akihiko Kameyama, Gang Liu, Hui Yang, Weijie Dong, Zhi Li, Lingling Jin, Hebin Sun, Xiaolin Cui, Jing Xu, Guoling Huang
Publikováno v:
Scientific Reports, Vol 9, Iss 1, Pp 1-10 (2019)
Scientific Reports
Scientific Reports
Western blotting is the most extensively used technique for the identification and characterisation of proteins and their expression levels. One of the major issues with this technique is the loss of proteins from the blotted membrane during the incu