Zobrazeno 1 - 10
of 165
pro vyhledávání: '"Akiharu Kubo"'
Autor:
Risa Kakuta, Keiji Tanese, Kenro Hirata, Katsura Emoto, Sakiko Takeuchi, Chihiro Shiiya, Masayuki Amagai, Akiharu Kubo
Publikováno v:
JEADV Clinical Practice, Vol 2, Iss 3, Pp 594-597 (2023)
Abstract Recently, immune checkpoint inhibitors have been administered for several cancers and have shown great efficacy. However, they are associated with various immune‐related adverse events. Here, we report a case with severe lichenoid eruption
Externí odkaz:
https://doaj.org/article/b74789de0217460d98e2cff48d6ab2ec
Autor:
Hisato Iriki, MD, PhD, Noriko Umegaki-Arao, MD, PhD, Risa Kakuta, MD, PhD, Harumi Fujita, PhD, Satomi Aoki, Masayuki Amagai, MD, PhD, Takashi Sasaki, PhD, Yasuo Hamamoto, MD, PhD, Robert Nakayama, MD, PhD, Akiharu Kubo, MD, PhD
Publikováno v:
JAAD Case Reports, Vol 25, Iss , Pp 89-92 (2022)
Externí odkaz:
https://doaj.org/article/6545edb8676945d5a3359f55b8767f6e
Autor:
Takayuki Miyamoto, Yoshitaka Honda, Kazushi Izawa, Nobuo Kanazawa, Saori Kadowaki, Hidenori Ohnishi, Masakazu Fujimoto, Naotomo Kambe, Naoya Kase, Takeshi Shiba, Yasuo Nakagishi, Shuji Akizuki, Kosaku Murakami, Masahiro Bamba, Yutaka Nishida, Ayano Inui, Tomoo Fujisawa, Daisuke Nishida, Naomi Iwata, Yoshikazu Otsubo, Shingo Ishimori, Momoko Nishikori, Kiminobu Tanizawa, Tomoyuki Nakamura, Takeshi Ueda, Yoko Ohwada, Yu Tsuyusaki, Masaki Shimizu, Takasuke Ebato, Kousho Iwao, Akiharu Kubo, Toshinao Kawai, Tadashi Matsubayashi, Tatsuhiko Miyazaki, Tomohiro Kanayama, Masahiko Nishitani-Isa, Hiroshi Nihira, Junya Abe, Takayuki Tanaka, Eitaro Hiejima, Satoshi Okada, Osamu Ohara, Megumu K. Saito, Junko Takita, Ryuta Nishikomori, Takahiro Yasumi
Publikováno v:
Frontiers in Immunology, Vol 13 (2022)
PurposeUpregulation of type I interferon (IFN) signaling has been increasingly detected in inflammatory diseases. Recently, upregulation of the IFN signature has been suggested as a potential biomarker of IFN-driven inflammatory diseases. Yet, it rem
Externí odkaz:
https://doaj.org/article/5700023cf0774dc68dac5c83825a3a61
Publikováno v:
Acta Dermato-Venereologica, Vol 101, Iss 9, p adv00549 (2021)
Externí odkaz:
https://doaj.org/article/17faac1da05c44f4919e146ab41135d1
Autor:
Matthias Rübsam, Aaron F. Mertz, Akiharu Kubo, Susanna Marg, Christian Jüngst, Gladiola Goranci-Buzhala, Astrid C. Schauss, Valerie Horsley, Eric R. Dufresne, Markus Moser, Wolfgang Ziegler, Masayuki Amagai, Sara A. Wickström, Carien M. Niessen
Publikováno v:
Nature Communications, Vol 8, Iss 1, Pp 1-16 (2017)
In multi-layered epithelia tight junctions (TJ) are confined to the most suprabasal viable layer. Here the authors show that this is regulated by ubiquitously localized E-cadherin tuning junctional tension and EGFR activity to inhibit TJ formation in
Externí odkaz:
https://doaj.org/article/13725cc72379417abbcc0dbb0fa23102
Autor:
Akimasa Adachi, Mayumi Komine, Takeo Maekawa, Satoru Murata, Aiko Shiohama, Akiharu Kubo, Mamitaro Ohtsuki
Publikováno v:
Acta Dermato-Venereologica, Vol 97, Iss 6, Pp 756-758 (2017)
Externí odkaz:
https://doaj.org/article/ff3d59d9a37b49ba998fd5b025857cc5
Autor:
Mariko Yokouchi, Toru Atsugi, Mark van Logtestijn, Reiko J Tanaka, Mayumi Kajimura, Makoto Suematsu, Mikio Furuse, Masayuki Amagai, Akiharu Kubo
Publikováno v:
eLife, Vol 5 (2016)
In multicellular organisms, cells adopt various shapes, from flattened sheets of endothelium to dendritic neurons, that allow the cells to function effectively. Here, we elucidated the unique shape of cells in the cornified stratified epithelia of th
Externí odkaz:
https://doaj.org/article/517aa6de09034e01bcb8847dbdcc8dc1
Autor:
Yasuhiko Asahina, Umi Tahara, Satomi Aoki, Kazuhiko Nakabayashi, Chiharu Tateishi, Daisuke Hayashi, Masayuki Amagai, Daisuke Tsuruta, Akiharu Kubo
Publikováno v:
European Journal of Human Genetics. 31(6):716-720
A prenatal second-hit genetic change that occurs on the wild-type allele in an embryo with a congenital pathogenic variant allele results in mosaicism of monoallelic and biallelic defect of the gene, which is called superimposed mosaicism. Superimpos
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::acd47467909027d4f8e2a42d1d29530b
https://hdl.handle.net/20.500.14094/0100482180
https://hdl.handle.net/20.500.14094/0100482180
Autor:
Ryo Tanaka, Yuichi Kurihara, Shohei Egami, Yasuko Saito, Takeshi Ouchi, Takeru Funakoshi, Hayato Takahashi, Noriko Umegaki‐Arao, Akiharu Kubo, Akiko Tanikawa, Masayuki Amagai, Jun Yamagami
Publikováno v:
The Journal of Dermatology. 50:203-211
Pemphigus and pemphigoid are autoimmune blistering diseases that affect mucosa and skin. Several clinical scoring systems, including the pemphigus disease area index (PDAI) and the bullous pemphigoid disease area index (BPDAI), have been validated fo
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::fae1f8d255ea9b7dcc89f5bb51fbc3cc
https://doi.org/10.1111/1346-8138.16532
https://doi.org/10.1111/1346-8138.16532
Autor:
Satoshi Nakamizo, Teruasa Murata, Yoshihiro Ishida, Satomi Aoki, Takashi Sasaki, Akiharu Kubo, Kenji Kabashima
Publikováno v:
The Journal of Dermatology.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::eb7839b8a97c15ba929cdd938e3500e1
https://doi.org/10.1111/1346-8138.16815
https://doi.org/10.1111/1346-8138.16815