Zobrazeno 1 - 9
of 9
pro vyhledávání: '"Akifumi Shioda"'
Autor:
Tetsuya Wakabayashi, Yuji Sano, Masayuki Mishima, Yoshika Iwata, Tatsuya Ikuno, Hirotake Shiraiwa, Akifumi Shioda, Asako Harada
Publikováno v:
Toxicology in vitro : an international journal published in association with BIBRA. 66
An emerging structure for anti-tumor antibody drugs utilizes a bispecific antibody (BiAb) that recognizes a tumor surface antigen and CD3 on T cells. An impurity that commonly contaminates these BiAb products is an anti-CD3 monoclonal antibody (mAb).
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::9bdb354769e049e5d97c5c82ae0a3f18
https://pubmed.ncbi.nlm.nih.gov/32247040
https://pubmed.ncbi.nlm.nih.gov/32247040
Autor:
Hans Peter Grimm, Yuichiro Sakamoto, Heinrich Bürgin, Akifumi Shioda, Wolfgang F. Richter, Jun Amano, Lutz Müller, Masami Suzuki, Ryo Takai, Yoshinobu Higuchi, Shuichi Chiba, Akinori Kawamura, Takayuki Sakurai
Publikováno v:
Birth Defects Research Part B: Developmental and Reproductive Toxicology. 98:170-182
Interleukin-6 (IL-6) is involved in the pathogenesis of multiple disorders, including juvenile autoimmune diseases. IL-6 participates in a broad spectrum of physiological events, and the IL-6 receptor (IL-6R) is widely distributed across multiple org
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::c30f06fe5157f2ecbc043c4bb57d54d5
https://doi.org/10.1002/bdrb.21053
https://doi.org/10.1002/bdrb.21053
Autor:
Tetsuya Mitsui, Mariko Yano, Koji Yamaguchi, Akifumi Shioda, Kenji Tanaka, Asako Harada, Masayuki Mishima, Akira Kawase, Akira Takeiri
Publikováno v:
Genes and Environment. 34:107-114
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::1cafa9fee5ef7b8d58b51eb5fe0b35cc
https://doi.org/10.3123/jemsge.34.107
https://doi.org/10.3123/jemsge.34.107
Autor:
Kenji Tanaka, Akira Takeiri, Takehiko Nohmi, Asako Harada, Masayuki Mishima, Akifumi Shioda, Kenichi Masumura
Publikováno v:
Genes and Environment. 29:89-99
Cisplatin is an active antitumor drug but its stereoisomer, i.e., transplatin, is clinically inactive. We characterized the gene mutations induced by both isomers using cell line GDL1 established from gpt delta transgenic mice. Because cisplatin exhi
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::8edf903a24826a4157dc5cb5cb6c66ec
https://doi.org/10.3123/jemsge.29.89
https://doi.org/10.3123/jemsge.29.89
Autor:
Takayuki, Sakurai, Ryo, Takai, Heinrich, Bürgin, Akifumi, Shioda, Yuichiro, Sakamoto, Jun, Amano, Hans Peter, Grimm, Wolfgang F, Richter, Yoshinobu, Higuchi, Shuichi, Chiba, Akinori, Kawamura, Masami, Suzuki, Lutz, Müller
Publikováno v:
Birth defects research. Part B, Developmental and reproductive toxicology. 98(2)
Interleukin-6 (IL-6) is involved in the pathogenesis of multiple disorders, including juvenile autoimmune diseases. IL-6 participates in a broad spectrum of physiological events, and the IL-6 receptor (IL-6R) is widely distributed across multiple org
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::3bc4503cabf145d58aaf1955dd96982a
https://pubmed.ncbi.nlm.nih.gov/23529913
https://pubmed.ncbi.nlm.nih.gov/23529913
Autor:
Kenji Tanaka, Akifumi Shioda, Akira Takeiri, Kazuto Watanabe, Masayuki Mishima, Kenichi Masumura, Asako Harada, Takehiko Nohmi
Publikováno v:
Mutation research. 609(1)
In order to create a novel in vitro test system for detection of large deletions and point mutations, we developed an immortalized cell line. A SV40 large T antigen expression unit was introduced into fibroblasts derived from gpt delta mouse lung tis
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::67b1041bbb41a8fdc866c879a454072f
https://pubmed.ncbi.nlm.nih.gov/16916616
https://pubmed.ncbi.nlm.nih.gov/16916616
Autor:
Ryosuke Watanabe, Keiji Terao, Keiji Mizoguchi, Tetsuro Sugimoto, Akifumi Shioda, Kazuto Watanabe
Publikováno v:
The Journal of toxicological sciences. 28(3)
We investigated the mechanism of hemolytic anemia detected in a repeated-dose toxicity study using cynomolgus monkeys that were treated with a humanized antibody drug. This drug was an IgG1 monoclonal antibody (MoAb) that binds to the human HM1.24 an
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::937f11b288f56a3da37a9d250f26e03b
https://pubmed.ncbi.nlm.nih.gov/12974605
https://pubmed.ncbi.nlm.nih.gov/12974605
Autor:
Kozo Fujisaki, Akifumi Shioda, Yoshitaka Omata, Takeshi Mikami, Masayuki Mishima, Hideyuki Nagasawa, Xuenan Xuan
Publikováno v:
The Journal of veterinary medical science. 63(4)
Numerous studies have supported the importance of immunity to SAG1, the most predominant antigen of Toxoplasma tachyzoite, in protection against Toxoplasma gondii infection. Nevertheless, vaccination with SAGI provides insufficient protection when co
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::0fc5f149ebd6057fe2e08a5dee625be3
https://pubmed.ncbi.nlm.nih.gov/11346179
https://pubmed.ncbi.nlm.nih.gov/11346179
Autor:
Tetsuya Kobayashi, Kazutoshi Yamamoto, Noriyuki Takahashi, Akifumi Shioda, Satoshi Miura, Sakae Kikuyama, Tom Kouki, Toshiki Nakai, Takeo Iwata
Publikováno v:
General and comparative endocrinology. 117(1)
Complementary DNA (cDNA) encoding newt (Cynops pyrrhogaster) growth hormone (nGH) was cloned from a cDNA library constructed from mRNAs of newt pituitary glands and was expressed in Escherichia coli. Based on Northern blot analysis using the cDNA as
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d071ba4d1c283a8015d94c069b6611d7
https://pubmed.ncbi.nlm.nih.gov/10620427
https://pubmed.ncbi.nlm.nih.gov/10620427