Zobrazeno 1 - 10
of 17
pro vyhledávání: '"Akie Okada"'
Autor:
Hiroaki Todo, Rina Niki, Akie Okada, Ibuki Narita, Kazuya Inamura, Ayu Ito, Shoko Itakura, Ichiro Hijikuro, Kenji Sugibayashi
Publikováno v:
Frontiers in Drug Delivery, Vol 3 (2023)
Non-lamellar liquid crystal (NLLC) structures have gained increasing attention for the controlled release of entrapped drugs. In the present study, an in situ NLLC structure-forming depot formulation through contact with water was developed using a t
Externí odkaz:
https://doaj.org/article/c9c6b2ca48e54baf8776b7e15015be95
Autor:
Ayu Ito, Shoko Itakura, Yuya Hasegawa, Miyu Hashimoto, Akie Okada, Mamoru Hirafuji, Hidenori Nakamura, Kenji Sugibayashi, Hiroaki Todo
Publikováno v:
Frontiers in Drug Delivery, Vol 3 (2023)
Patients receiving chemotherapy by intravenous (i.v.) or oral administration of anticancer drugs often experience side effects. In this study, an electro-osmotic flow (EO) pump was used for the direct administration of an anticancer drug with minimum
Externí odkaz:
https://doaj.org/article/4bb2d619a61945f5bc998ac069e0bd7b
Autor:
Akie Okada, Rina Niki, Yutaka Inoue, Junki Tomita, Hiroaki Todo, Shoko Itakura, Kenji Sugibayashi
Publikováno v:
Pharmaceutics, Vol 14, Iss 4, p 785 (2022)
In recent years, the development of self-injectable formulations has attracted much attention, and the development of formulations to control pharmacokinetics, as well as drug release and migration in the skin, has become an active research area. In
Externí odkaz:
https://doaj.org/article/93aede3a775c4e119d7af268cac7bd7b
Publikováno v:
Pharmaceutics, Vol 10, Iss 4, p 163 (2018)
N-Palmitoyl-Glycine-Histidine (Pal-GH) is a novel low molecular weight gelator. In our previous report, ivermectin, a lipophilic drug, was effectively delivered to skin tissue after topical application with Pal-GH as a spray gel formulation, and a mu
Externí odkaz:
https://doaj.org/article/d3535d6babc146cba598f7c0a630310d
Publikováno v:
Chemical and Pharmaceutical Bulletin. 69:727-733
Recently, a novel humidifier that sprays water fine droplets equipped with a copolymer, poly(3,4-ethylene dioxythiophene)-poly(styrene sulfonate) (PEDOT/PSS) was developed. PEDOT/PSS in the humidifier absorbs water from the environment and releases f
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c72155500af80ddc583f6a0b43c76ee3
https://doi.org/10.1248/cpb.c21-00110
https://doi.org/10.1248/cpb.c21-00110
Publikováno v:
Pharmaceutical Research
Purpose: Non-lamellar liquid crystal (NLLC)-forming lipids have gained attention as a novel component because of their ability to self-assemble upon contact with body fluids. In this study, a novel NLLC-forming lipid, mono-O-(5, 9, 13-trimethyl-4-tet
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::3bac8adec33d6909c7e27df8e482982f
http://europepmc.org/articles/PMC7909736
http://europepmc.org/articles/PMC7909736
Publikováno v:
Chemical and Pharmaceutical Bulletin. 68:1025-1033
We examined the physicochemical and biochemical properties of mono-O-(5,9,13-trimethyl-4-tetradecenyl)glycerol ester (MGE), including ease of handling, high bioadhesiveness, quick and stable in vivo self-organization (forming a non-lamellar lyotropic
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::19793e09093011e7e3e9b6269b0aa04c
https://doi.org/10.1248/cpb.c20-00333
https://doi.org/10.1248/cpb.c20-00333
Publikováno v:
International Journal of Pharmaceutics. 577:1-9
Skin offers an easily accessible and convenient site for the administration of drugs. Therefore, the development of injectable formulations with controlled drug release properties are now expected to deliver middle- and large-size biomolecules. In th
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::6c8f150ee5403605deb724d9fe60d29d
https://libir.josai.ac.jp/il/meta_pub/G0000284repository_JOS-j.ijpharm.2019.118944
https://libir.josai.ac.jp/il/meta_pub/G0000284repository_JOS-j.ijpharm.2019.118944
Autor:
Muhammad Fikri Bin Mohd Fadli, Sabrina Dahlizar, Masanori Katakura, Akie Okada, Hiroaki Todo, Gerard Lee See, Florencio Arce, Shoko Itakura, Kenji Sugibayashi, Ichiro Hijikuro
Publikováno v:
Journal of controlled release : official journal of the Controlled Release Society. 325
Intranasal administration is poised as a competent method in delivering drugs to the brain, because the nasal route has a direct link with the central nervous system bypassing the formidable blood-brain barrier. C17-monoglycerol ester (MGE) and glyce
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ef6fa4be27126620f47be2712f8051bb
https://pubmed.ncbi.nlm.nih.gov/32598958
https://pubmed.ncbi.nlm.nih.gov/32598958
Publikováno v:
Journal of Drug Delivery Science and Technology. 44:58-64
This study attempted to identify a good selection method for phospholipids to design liposome preparations with high skin penetration-enhancing effects. Five kinds of phosphatidylcholines and phosphatidylglycerols each were selected. First, phospholi
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b5ac33ec9fd4d29614d1ada8b4d73977
https://doi.org/10.1016/j.jddst.2017.11.021
https://doi.org/10.1016/j.jddst.2017.11.021