Zobrazeno 1 - 10 of 35 pro vyhledávání: '"Akie Maehara"'
1
Akademický článek
Neuronal substance P-driven MRGPRX2-dependent mast cell degranulation products differentially promote vascular permeability
Autor: Masakazu Nagamine, Ayako Kaitani, Kumi Izawa, Tomoaki Ando, Akihisa Yoshikawa, Masahiro Nakamura, Akie Maehara, Risa Yamamoto, Yoko Okamoto, Hexing Wang, Hiromichi Yamada, Keiko Maeda, Nobuhiro Nakano, Toshiaki Shimizu, Hideoki Ogawa, Ko Okumura, Jiro Kitaura
Publikováno v: Frontiers in Immunology, Vol 15 (2024)
Mas-related G protein-coupled receptor b2 (Mrgprb2) binding to its cationic endogenous and exogenous ligands induces mast cell degranulation and promotes inflammation in mice. However, the physiological roles of its human homologue MRGPRX2 remain unc
Externí odkaz: https://doaj.org/article/67499c2594a54902b0e3692c6995aefd
Zobrazit plný text záznamu
2
Akademický článek
Intranasal administration of ceramide liposome suppresses allergic rhinitis by targeting CD300f in murine models
Autor: Takuma Ide, Kumi Izawa, Wahyu Diono, Anna Kamei, Tomoaki Ando, Ayako Kaitani, Akie Maehara, Akihisa Yoshikawa, Risa Yamamoto, Shino Uchida, Hexing Wang, Mayuki Kojima, Keiko Maeda, Nobuhiro Nakano, Masahiro Nakamura, Toshiaki Shimizu, Hideoki Ogawa, Ko Okumura, Fumihiko Matsumoto, Katsuhisa Ikeda, Motonobu Goto, Jiro Kitaura
Publikováno v: Scientific Reports, Vol 14, Iss 1, Pp 1-15 (2024)
Abstract Allergic rhinitis (AR) is caused by type I hypersensitivity reaction in the nasal tissues. The interaction between CD300f and its ligand ceramide suppresses immunoglobulin E (IgE)-mediated mast cell activation. However, whether CD300f inhibi
Externí odkaz: https://doaj.org/article/86f2797652e548cc944bc465f4ee2c59
Zobrazit plný text záznamu
3
Akademický článek
Murine model identifies tropomyosin as IgE cross-reactive protein between house dust mite and coho salmon that possibly contributes to the development of salmon allergy
Autor: Risa Yamamoto, Kumi Izawa, Tomoaki Ando, Ayako Kaitani, Atsushi Tanabe, Hiromichi Yamada, Shino Uchida, Akihisa Yoshikawa, Yasuharu Kume, Shun Toriumi, Akie Maehara, Hexing Wang, Masakazu Nagamine, Naoko Negishi, Nobuhiro Nakano, Nobuyuki Ebihara, Toshiaki Shimizu, Hideoki Ogawa, Ko Okumura, Jiro Kitaura
Publikováno v: Frontiers in Immunology, Vol 14 (2023)
BackgroundRecently, we have developed a method to identify IgE cross-reactive allergens. However, the mechanism by which IgE cross-reactive allergens cause food allergy is not yet fully understood how. In this study, we aimed to understand the underl
Externí odkaz: https://doaj.org/article/395c411aa5cd42189715112e200e5e73
Zobrazit plný text záznamu
4
Akademický článek
Staphylococcus aureus δ-toxin present on skin promotes the development of food allergy in a murine model
Autor: Hiromichi Yamada, Ayako Kaitani, Kumi Izawa, Tomoaki Ando, Anna Kamei, Shino Uchida, Akie Maehara, Mayuki Kojima, Risa Yamamoto, Hexing Wang, Masakazu Nagamine, Keiko Maeda, Koichiro Uchida, Nobuhiro Nakano, Yoshikazu Ohtsuka, Hideoki Ogawa, Ko Okumura, Toshiaki Shimizu, Jiro Kitaura
Publikováno v: Frontiers in Immunology, Vol 14 (2023)
BackgroundPatients with food allergy often suffer from atopic dermatitis, in which Staphylococcus aureus colonization is frequently observed. Staphylococcus aureus δ-toxin activates mast cells and promotes T helper 2 type skin inflammation in the ta
Externí odkaz: https://doaj.org/article/e445b93ce4be4f868a2491362ea214fd
Zobrazit plný text záznamu
5
Akademický článek
Development of mouse model for oral allergy syndrome to identify IgE cross-reactive pollen and food allergens: ragweed pollen cross-reacts with fennel and black pepper
Autor: Anna Kamei, Kumi Izawa, Tomoaki Ando, Ayako Kaitani, Risa Yamamoto, Akie Maehara, Takuma Ide, Hiromichi Yamada, Mayuki Kojima, Hexing Wang, Koji Tokushige, Nobuhiro Nakano, Toshiaki Shimizu, Hideoki Ogawa, Ko Okumura, Jiro Kitaura
Publikováno v: Frontiers in Immunology, Vol 13 (2022)
Oral allergy syndrome (OAS) is an IgE-mediated immediate food allergy that is localized to the oral mucosa. Pollen food allergy syndrome (PFAS), a pollinosis-associated OAS, is caused by cross-reactivity between food and pollen allergens. However, we
Externí odkaz: https://doaj.org/article/3f853d76cc5d4984b142228d15e63824
Zobrazit plný text záznamu
6
Akademický článek
Disrupting ceramide-CD300f interaction prevents septic peritonitis by stimulating neutrophil recruitment
Autor: Kumi Izawa, Akie Maehara, Masamichi Isobe, Yuka Yasuda, Makoto Urai, Yasutaka Hoshino, Keigo Ueno, Toshihiro Matsukawa, Mariko Takahashi, Ayako Kaitani, Emiko Shiba, Ayako Takamori, Shino Uchida, Koichiro Uchida, Keiko Maeda, Nobuhiro Nakano, Yoshinori Yamanishi, Toshihiko Oki, David Voehringer, Axel Roers, Susumu Nakae, Junko Ishikawa, Yuki Kinjo, Toshiaki Shimizu, Hideoki Ogawa, Ko Okumura, Toshio Kitamura, Jiro Kitaura
Publikováno v: Scientific Reports, Vol 7, Iss 1, Pp 1-13 (2017)
Abstract Sepsis is a serious clinical problem. Negative regulation of innate immunity is associated with sepsis progression, but the underlying mechanisms remains unclear. Here we show that the receptor CD300f promotes disease progression in sepsis.
Externí odkaz: https://doaj.org/article/aa59ba0107c3416ea07d058e0838adee
Zobrazit plný text záznamu

Vyhledávací nástroje:

Upřesnit hledání

Omezení vyhledávání
Plný text Recenzováno Digitální knihovna AV ČR
Zdroje