Zobrazeno 1 - 10
of 23
pro vyhledávání: '"Akie, Yamahira"'
Publikováno v:
International Journal of Medical Sciences, Vol 9, Iss 10, Pp 901-908 (2012)
Quantification of tumor-associated mRNA extracted from blood cells/tissues containing tumor cells is used for evaluation of treatment efficacy or residual tumor cell burden in tumors including leukemia. However, this method using tumor cell-containin
Externí odkaz:
https://doaj.org/article/6fa610ebd6bf49918ede402a09705804
Autor:
Atsushi Shiga, Tomohiko Ishihara, Akinori Miyashita, Misaki Kuwabara, Taisuke Kato, Norihiro Watanabe, Akie Yamahira, Chigusa Kondo, Akio Yokoseki, Masuhiro Takahashi, Ryozo Kuwano, Akiyoshi Kakita, Masatoyo Nishizawa, Hitoshi Takahashi, Osamu Onodera
Publikováno v:
PLoS ONE, Vol 7, Iss 8, p e43120 (2012)
Amyotrophic lateral sclerosis (ALS) is an adult-onset neurodegenerative disease caused by selective loss of motor neurons. In the ALS motor neurons, TAR DNA-binding protein of 43 kDa (TDP-43) is dislocated from the nucleus to cytoplasm and forms incl
Externí odkaz:
https://doaj.org/article/fd6d5c3d72e94dc3a0cac8c1ae4623f7
Autor:
Takayoshi Uchiyama, Masuhiro Takahashi, Hirohito Sone, Tatsuo Furukawa, Minami Iwabuchi, Miwako Narita, Aya Kojima, Naoya Satoh, Akie Yamahira, Anri Saito
Publikováno v:
International Journal of Medical Sciences
Quantification of tumor-associated mRNA extracted from blood cells/tissues containing tumor cells is used for evaluation of treatment efficacy or residual tumor cell burden in tumors including leukemia. However, this method using tumor cell-containin
Direct effect of dasatinib on proliferation and cytotoxicity of natural killer cells inin vitrostudy
Autor:
Takayoshi Uchiyama, Miwako Narita, Tatsuo Furukawa, Naoya Sato, Minami Iwabuchi, Hirohito Sone, Akie Yamahira, Masuhiro Takahashi
Publikováno v:
Hematological Oncology. 31:156-163
Lymphocytosis predominantly due to natural killer (NK) cells has been reported in nearly a half of chronic myelogenous leukemia (CML) patients who were being treated with dasatinib. Besides, dasatinib-treated patients with lymphocytosis have a better
Autor:
Akie Yamahira, Miwako Narita, Masahide Takahashi, Ken Toba, Takeshi Nakamura, Y. Aizawa, Tatsuo Furukawa, Ichiro Fuse, Norihiro Watanabe, Masayoshi Masuko
Publikováno v:
International Journal of Laboratory Hematology. 33:378-390
SUMMARY Introduction: Although the roles of each low-frequency immunocom- petent cells such as dendritic cells (DCs), cdT cells, and Treg cells in induction of acute or chronic graft versus host disease (GVHD) have been discussed in several reports,
Autor:
Shigeo Hashimoto, Ichiro Fuse, Norihiro Watanabe, Tatsuo Furukawa, Akie Yamahira, Ken Toba, Miwako Narita, Yoshifusa Aizawa, Nozomi Tochiki, Anri Saitoh, Masuhiro Takahashi, Masami Kaji, Takeshi Nakamura
Publikováno v:
Leukemia Research. 34:1517-1524
We investigated the transformation from pDCs to mDCs in a pDC line (PMDC05) which was established from a patient with pDC leukemia in our laboratory. PMDC05 cells were separated into two fractions according to the expression of BDCA1 and CD123. BDCA1
Autor:
Tatsuo Furukawa, Masayoshi Masuko, Yoshifusa Aizawa, Masami Kaji, Norihiro Watanabe, Masuhiro Takahashi, Nozomi Tochiki, Ken Toba, Akie Yamahira, Miwako Narita, Anri Saitoh, Ichiro Fuse, Takeshi Nakamura
Publikováno v:
Medical Oncology. 28:219-230
Although antigen-specific immune responses including cytotoxic T cells (CTLs) against antigen peptide could be enhanced after tumor antigen peptide vaccinations, the immune responses do not necessarily result in a decrease or eradication of tumor cel
Autor:
Masami Kaji, Takeshi Nakamura, Nozomi Tochiki, Ken Toba, Akie Yamahira, Miwako Narita, Norihiro Watanabe, Anri Saitoh, Yoshifusa Aizawa, Ichiro Fuse, Tatsuo Furukawa, Shigeo Hashimoto, Masuhiro Takahashi
Publikováno v:
Leukemia Research. 33:1224-1232
We established a plasmacytoid dendritic cell (pDC) line (PMDC05) from leukemia cells of pDC leukemia. PMDC05 cells were positive for CD4, CD56, CD33, HLA-DR, CD123 (IL-3Ralpha) and CD86 in the absence of lineage markers. mRNA of TLR1, TLR2, TLR4, TLR
Autor:
Akie, Yamahira, Miwako, Narita, Minami, Iwabuchi, Takayoshi, Uchiyama, Shunpei, Iwaya, Rie, Ohiwa, Yoshinori, Nishizawa, Takafumi, Suzuki, Yusaku, Yokoyama, Shigeo, Hashimoto, Jun, Takizawa, Hirohito, Sone, Masuhiro, Takahashi
Publikováno v:
Anticancer research. 34(8)
Indoleamine-2,3-dioxygenase (IDO) is a rate-limiting enzyme for tryptophan metabolism and plays an immunosuppressive role. Antigen-presenting cells, when activated, increase the expression of IDO, which results in the suppression of subsequent immune
Autor:
Takayoshi, Uchiyama, Naoya, Sato, Miwako, Narita, Akie, Yamahira, Minami, Iwabuchi, Tatsuo, Furukawa, Hirohito, Sone, Masuhiro, Takahashi
Publikováno v:
Hematological oncology. 31(3)
Lymphocytosis predominantly due to natural killer (NK) cells has been reported in nearly a half of chronic myelogenous leukemia (CML) patients who were being treated with dasatinib. Besides, dasatinib-treated patients with lymphocytosis have a better