Zobrazeno 1 - 10
of 35
pro vyhledávání: '"Aki Uchida"'
Autor:
Aki Uchida, Juliet F. Zechner, Bharath K. Mani, Won-mee Park, Vincent Aguirre, Jeffrey M. Zigman
Publikováno v:
Molecular Metabolism, Vol 3, Iss 7, Pp 717-730 (2014)
The current study examined potential mechanisms for altered circulating ghrelin levels observed in diet-induced obesity (DIO) and following weight loss resulting from Roux-en-Y gastric bypass (RYGB). We hypothesized that circulating ghrelin levels we
Externí odkaz:
https://doaj.org/article/7d408b912eaa413c9949224b3825cb9d
Publikováno v:
PLoS ONE, Vol 10, Iss 10, p e0139960 (2015)
Leptin, the protein product of the ob gene, increases energy expenditure and reduces food intake, thereby promoting weight reduction. Leptin also regulates glucose homeostasis and hepatic insulin sensitivity via hypothalamic proopiomelanocortin neuro
Externí odkaz:
https://doaj.org/article/48692c7f6fd44cb7981054df9c5ef366
Autor:
Eric D. Berglund, Robert W. Arpke, Jonathan M. Graff, Daniel C. Berry, Michael Kyba, Elizabeth L. Close, Aki Uchida, Yuwei Jiang, David W. Reading
Publikováno v:
Cell Metabolism. 25:166-181
Cold temperatures induce progenitor cells within white adipose tissue to form beige adipocytes that burn energy and generate heat; this is a potential anti-diabesity therapy. However, the potential to form cold-induced beige adipocytes declines with
Autor:
Joao A.G. Duarte, Jeffrey D. Browning, Austin Potts, Mark A. Magnuson, Xiaorong Fu, Stanislaw Deja, Aki Uchida, Shawn C. Burgess, Eric D. Berglund, Blanka Kucejova
Cytosolic phosphoenolpyruvate carboxykinase (PEPCK) is a gluconeogenic enzyme that is highly expressed in the liver and kidney but is also expressed at lower levels in a variety of other tissues where it may play adjunct roles in fatty acid esterific
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c60279d22c495fbae18352001573828a
https://europepmc.org/articles/PMC6139646/
https://europepmc.org/articles/PMC6139646/
Autor:
Hiroshi Nishihara, Junpei Yuasa, Taka Aki Uchida, Koichi Nozaki, Yoshinori Yamanoi, Ryoma Ishii, Shinya Koga, Munetaka Iwamura, Masaki Shimada, Yu Kurihara, Tsuyoshi Kawai, Shuhei Ueki
Publikováno v:
The Journal of organic chemistry. 82(12)
Asymmetric arylation of secondary silanes catalyzed by a Pd-chiral phosphoramidite complex was developed for application to low-molecular-weight circularly polarized luminescence (CPL) materials. The asymmetric arylation provided a convenient, effici
Autor:
Yuki Yonenaga, Koichiro Hayashi, Taka-aki Uchida, Munetaka Iwamura, Tatsuya Itou, Kazuhisa Fujimoto, Koichi Nozaki, Masahiko Inouye
Publikováno v:
Angewandte Chemie International Edition. 53:14392-14396
The Sonogashira coupling of γ-CD-encapsulated alkynylpyrenes with terphenyl-type stopper molecules gave a doubly alkynylpyrene-threaded [4]rotaxane. The rotaxane showed only excimer emission, with a high fluorescence quantum yield of Φf =0.37, aris
Autor:
Joel K. Elmquist, Christina A. Mosher, Jeffrey M. Zigman, Tiemin Liu, Sherri Osborne-Lawrence, Eric D. Berglund, Qian Wang, Brittany L. Mason, Aki Uchida, Angela K. Walker, Chen Liu, Jen Chieh Chuang
Publikováno v:
Molecular Metabolism
The hormone ghrelin stimulates eating and helps maintain blood glucose upon caloric restriction. While previous studies have demonstrated that hypothalamic arcuate AgRP neurons are targets of ghrelin, the overall relevance of ghrelin signaling within
Autor:
Romain Christiano, Robert V. Farese, Huajin Wang, Florian Wilfling, Tobias C. Walther, Morven Graham, Joel T. Haas, Rosalind A. Coleman, Kimberly K. Buhman, Florian Fröhlich, Joerg Bewersdorf, Ji-Xin Cheng, Xinran Liu, Natalie Krahmer, Aki Uchida, Travis J. Gould
Publikováno v:
Developmental Cell. 24(4):384-399
SummaryLipid droplets (LDs) store metabolic energy and membrane lipid precursors. With excess metabolic energy, cells synthesize triacylglycerol (TG) and form LDs that grow dramatically. It is unclear how TG synthesis relates to LD formation and grow
Publikováno v:
Chemistry, an Asian journal. 11(17)
Circularly polarized luminescence (CPL) was observed from [Eu(dppda)2 ](-) (dppda=4,7-diphenyl-1,10-phenanthroline-2,9-dicarboxylic acid) and [Eu(pzpda)2 ](-) (pzpda=pyrazino[2,3-f][1,10]phenanthroline-7,10-dicarboxylic acid) in aqueous solutions con
Publikováno v:
Clinical & Experimental Metastasis. 28:733-741
We previously described a lipid-accumulating phenotype of estrogen receptor negative (ER(-)) breast cancer cells exemplified by the MDA-MB-231 and MDA-MB-436 cell lines. These cells had more lipid droplets, a higher uptake of oleic acid and LDL, a hi