Zobrazeno 1 - 10
of 34
pro vyhledávání: '"Aki Takimoto"'
Autor:
Shinsei Yambe, Yuki Yoshimoto, Kazutaka Ikeda, Koichiro Maki, Aki Takimoto, Akihide Tokuyama, Shinnosuke Higuchi, Xinyi Yu, Kenta Uchibe, Shigenori Miura, Hitomi Watanabe, Tetsushi Sakuma, Takashi Yamamoto, Kotaro Tanimoto, Gen Kondoh, Masataka Kasahara, Toshihide Mizoguchi, Denitsa Docheva, Taiji Adachi, Chisa Shukunami
Publikováno v:
Frontiers in Cell and Developmental Biology, Vol 12 (2024)
Fibrocartilaginous entheses consist of tendons, unmineralized and mineralized fibrocartilage, and subchondral bone, each exhibiting varying stiffness. Here we examined the functional role of sclerostin, expressed in mature mineralized fibrochondrocyt
Externí odkaz:
https://doaj.org/article/427052bd41564fbcaaa067f05c89e21b
Autor:
Kiminori Yukata, Chisa Shukunami, Yoshito Matsui, Aki Takimoto, Tomohiro Goto, Mitsuhiko Takahashi, Atsushi Mihara, Tetsuya Seto, Takashi Sakai, Yuji Hiraki, Natsuo Yasui
Publikováno v:
PLoS ONE, Vol 18, Iss 2 (2023)
Chondromodulin (Cnmd) is a glycoprotein known to stimulate chondrocyte growth. We examined in this study the expression and functional role of Cnmd during distraction osteogenesis that is modulated by mechanical forces. The right tibiae of the mice w
Externí odkaz:
https://doaj.org/article/a043a9130ce0427fa1c173fc0ced48cb
Autor:
Katsumasa Ideo, Takuya Tokunaga, Chisa Shukunami, Aki Takimoto, Yuki Yoshimoto, Ryuji Yonemitsu, Tatsuki Karasugi, Hiroshi Mizuta, Yuji Hiraki, Takeshi Miyamoto
Publikováno v:
PLoS ONE, Vol 15, Iss 12, p e0242286 (2020)
A multipotent cell population co-expressing a basic-helix-loop-helix transcription factor scleraxis (Scx) and SRY-box 9 (Sox9) has been shown to contribute to the establishment of entheses (tendon attachment sites) during mouse embryonic development.
Externí odkaz:
https://doaj.org/article/71dd67dfc26943afb3f5a20815ac82be
Autor:
Chisa Shukunami, DDS, PhD, Yuki Yoshimoto, DVM, PhD, Aki Takimoto, PhD, Hiroshi Yamashita, PhD, Yuji Hiraki, PhD
Publikováno v:
Japanese Dental Science Review, Vol 52, Iss 4, Pp 84-92 (2016)
Tendons and ligaments are dense fibrous bands of connective tissue that integrate musculoskeletal components in vertebrates. Tendons connect skeletal muscles to the bone and function as mechanical force transmitters, whereas ligaments bind adjacent b
Externí odkaz:
https://doaj.org/article/59412829ce914130bac4edfce7f2fd03
Autor:
Long Guo, Hiroshi Yamashita, Ikuyo Kou, Aki Takimoto, Makiko Meguro-Horike, Shin-ichi Horike, Tetsushi Sakuma, Shigenori Miura, Taiji Adachi, Takashi Yamamoto, Shiro Ikegawa, Yuji Hiraki, Chisa Shukunami
Publikováno v:
PLoS Genetics, Vol 12, Iss 1, p e1005802 (2016)
Previously, we identified an adolescent idiopathic scoliosis susceptibility locus near human ladybird homeobox 1 (LBX1) and FLJ41350 by a genome-wide association study. Here, we characterized the associated non-coding variant and investigated the fun
Externí odkaz:
https://doaj.org/article/43be7d57ee104c5fb35c031b3296a3fa
Autor:
Shigenori Miura, Jun Kondo, Aki Takimoto, Hiroko Sano-Takai, Long Guo, Chisa Shukunami, Hideyuki Tanaka, Yuji Hiraki
Publikováno v:
PLoS ONE, Vol 9, Iss 4, p e94239 (2014)
Chondromodulin-I (ChM-I) is a 20-25 kDa anti-angiogenic glycoprotein in cartilage matrix. In the present study, we identified a novel 14-kDa species of ChM-I by immunoblotting, and purified it by immunoprecipitation with a newly raised monoclonal ant
Externí odkaz:
https://doaj.org/article/889130535b12493faed50c1c92e22cf9
Autor:
Yuji Hiraki, Aki Takimoto, Chisa Shukunami, Takeshi Miyamoto, Katsumasa Ideo, Takuya Tokunaga, Hiroshi Mizuta, Yuki Yoshimoto, Tatsuki Karasugi, Ryuji Yonemitsu
Publikováno v:
PLoS ONE, Vol 15, Iss 12, p e0242286 (2020)
PLoS ONE
PLoS ONE
A multipotent cell population co-expressing a basic-helix-loop-helix transcription factor scleraxis (Scx) and SRY-box 9 (Sox9) has been shown to contribute to the establishment of entheses (tendon attachment sites) during mouse embryonic development.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a5da7b215237c57c59c203ad6ccd26f4
https://doaj.org/article/71dd67dfc26943afb3f5a20815ac82be
https://doaj.org/article/71dd67dfc26943afb3f5a20815ac82be
Autor:
Masayoshi Kawatsu, Seiji Kimura, Aki Takimoto, Teruko Takano-Yamamoto, Arata Ito, Chisa Shukunami, Yuki Yoshimoto, Yuji Hiraki, Tadafumi Kawamoto, Nobuo Takeshita, Masahiro Seiryu
Publikováno v:
Bone. 149:115969
During tooth movement in orthodontic treatment, bone formation and resorption occur on the tension and compression sides of the alveolar bone, respectively. Although the bone formation activity increases in the periodontal ligament (PDL) on the tensi
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::94ddef7678816f3356b9369e58692507
https://doi.org/10.1016/j.bone.2021.115969
https://doi.org/10.1016/j.bone.2021.115969
Publikováno v:
Japanese Dental Science Review, Vol 52, Iss 4, Pp 84-92 (2016)
The Japanese Dental Science Review
The Japanese Dental Science Review
Summary Tendons and ligaments are dense fibrous bands of connective tissue that integrate musculoskeletal components in vertebrates. Tendons connect skeletal muscles to the bone and function as mechanical force transmitters, whereas ligaments bind ad
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::9835ad26a6a7da494b412f1ed6ad156c
http://www.sciencedirect.com/science/article/pii/S1882761616300072
http://www.sciencedirect.com/science/article/pii/S1882761616300072
Autor:
Gen Kondoh, Takashi Yamamoto, Chikara Kokubu, Chisa Shukunami, Hitomi Watanabe, Aki Takimoto, Tetsushi Sakuma, Yuji Hiraki
Publikováno v:
Scientific Reports
Scientific Reports, Vol 9, Iss 1, Pp 1-16 (2019)
Scientific Reports, Vol 9, Iss 1, Pp 1-16 (2019)
A previously identified enhancer 10 kb upstream of the Aggrecan (Acan) gene (UE) can drive cartilage specific reporter expression in vivo. Here, we report that the paralogous transcription factors PAX1 and PAX9 differentially drive UE, depending on t
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::373dafbe1f680f8b4a5e9f10695c4e95
https://pubmed.ncbi.nlm.nih.gov/30872687
https://pubmed.ncbi.nlm.nih.gov/30872687