Zobrazeno 1 - 3
of 3
pro vyhledávání: '"Aki Takeshima"'
Autor:
Naoyuki Kotoku, Shunichi Shibuya, Masaki Nogata, Aoi Ito, Aki Takeshima, Motomasa Kobayashi, Kanako Mizuno
Publikováno v:
Tetrahedron. 73:1342-1349
An improved method for synthesizing structurally simplified analogs of cortistatin A (1), a novel anti-angiogenic steroidal alkaloid from a marine sponge, was developed. In contrast to previous methods, step- and redox-economical synthesis was achiev
Autor:
Takuya Okamoto, Takeshi Tanaka, Takeshi Kodama, Hiroshi Kida, Yoshimitsu Tachi, Hiromi Inui, Yoshiki Morimoto, Aki Takeshima
Publikováno v:
ChemInform. 42
Key steps of the described synthesis are the diastereoselective construction of a diaryl-substituted stereogenic center by an intramolecular Pd-catalyze α-C-arylation and subsequent direct conversion of the vinologous imid function into the C2-C25 d
Autor:
Hiroshi Kida, Yoshimitsu Tachi, Hiromi Inui, Takeshi Tanaka, Yoshiki Morimoto, Takeshi Kodama, Takuya Okamoto, Aki Takeshima
Publikováno v:
Chemical Communications. 47:2949
The characteristic indeno-tetrahydropyridine core of cytotoxic haouamine B (2) was efficiently synthesized featuring the diastereoselective construction of a diaryl-substituted stereogenic quaternary center by an intramolecular Pd-catalyzed α-C-aryl