Zobrazeno 1 - 6
of 6
pro vyhledávání: '"Aki Kawagishi"'
Autor:
Yoshikazu Iwasawa, Takahiro Ogawa, Takumitsu Machida, Aki Kawagishi, Akiko Osada, Kenichi Matsuo, Teruhiro Utsugi, Satoshi Yamashita, Ryo Hatanaka, Kenjiro Ito, Tadashi Imaoka
Publikováno v:
Molecular Cancer Therapeutics. 17:A169-A169
Background: Lysine-specific demethylase 1A (LSD1/KDM1A) is a flavin adenine dinucleotide (FAD)-dependent histone demethylase that specifically modifies histone H3 lysine 4 and lysine 9. LSD1 activity is implicated in the pathogenesis of several human
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::053c529424e1a9d4d0cbc7f813e0f71c
https://doi.org/10.1158/1535-7163.targ-17-a169
https://doi.org/10.1158/1535-7163.targ-17-a169
Autor:
Hideki Kurihara, Hisashi Ohta, Aki Kawagishi, Masayuki Nakamura, Morihiro Mitsuya, Gentaroh Suzuki, Naohiro Tsukamoto, Hiroshi Fushiki, Mitsuru Ohkubo
Publikováno v:
Journal of Pharmacology and Experimental Therapeutics. 323:147-156
Novel isoxazolopyridone derivatives that are metabotropic glutamate receptor (mGluR) 7 antagonists were discovered and pharmacologically characterized. 5-Methyl-3,6-diphenylisoxazolo[4,5- c ]pyridin-4(5 H )-one (MDIP) was identified by random screeni
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::dc0ca64032631f3f52fe8e63152786ee
https://doi.org/10.1124/jpet.107.124701
https://doi.org/10.1124/jpet.107.124701
Autor:
Aki Kawagishi, Toshiharu Hayashi, Akikazu Sakudo, Yoshitsugu Matsumoto, Atsutaka Kubosaki, Keiichi Saeki, Natsumi Takeyama, Takashi Onodera
Publikováno v:
Biochemical and Biophysical Research Communications. 310:791-795
Encephalomyocarditis (EMC) virus induces insulin-dependent diabetes and myocarditis in several strains of mice. The T-cell receptor (TCR) Vbeta genes of infiltrating T cells in the pancreas and myocardium of BALB/C mice infected with EMC virus D-vari
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a4c5fd30d852c450fc6b9fdbe9391b33
https://doi.org/10.1016/j.bbrc.2003.09.078
https://doi.org/10.1016/j.bbrc.2003.09.078
Publikováno v:
Molecular Cancer
Molecular Cancer, Vol 8, Iss 1, p 44 (2009)
Molecular Cancer, Vol 8, Iss 1, p 44 (2009)
Background The Hedgehog (HH) pathway promotes tumorigenesis in a diversity of cancers. Activation of the HH signaling pathway is caused by overexpression of HH ligands or mutations in the components of the HH/GLI1 cascade, which lead to increased tra
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::8432e450086b1cf59dc4e973c001e0b4
https://doi.org/10.1186/1476-4598-8-44
https://doi.org/10.1186/1476-4598-8-44
Publikováno v:
Molecular Cancer Therapeutics. 12:A274-A274
Background: Diffuse large B-cell lymphoma (DLBCL) has two major subtypes with distinct biological and clinical characteristics: activated B-cell like (ABC) and germinal center B-cell like (GCB) lymphoma. A Bruton's tyrosine kinase (BTK) inhibitor has
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::5d0119b2f7f68950cae31acf1d6e4016
https://doi.org/10.1158/1535-7163.targ-13-a274
https://doi.org/10.1158/1535-7163.targ-13-a274
Autor:
Shingo Tsuji, Keiko Ishihara, Hideya Komatani, Naoko Fujino, Aki Kawagishi, Yoshio Ogino, Yoko Nakatsuru, Jiro Kuze, Teruhiro Utsugi, Hiroki Irie
Publikováno v:
Molecular Cancer Therapeutics. 12:A273-A273
Background: Chronic activation of the B-cell receptor (BCR) pathway is critical for proliferation and survival of malignant B cells, and is implicated in the pathogenesis of B-cell lymphomas. Spleen tyrosine kinase (SYK) is a central regulator of the
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::a1b1f3117e4c804102045605f5fa787e
https://doi.org/10.1158/1535-7163.targ-13-a273
https://doi.org/10.1158/1535-7163.targ-13-a273