Zobrazeno 1 - 10
of 50
pro vyhledávání: '"Aki, SUGANO"'
Autor:
Tomohiko Yamamura, Tomoko Horinouchi, Tomomi Adachi, Maki Terakawa, Yutaka Takaoka, Kohei Omachi, Minoru Takasato, Kiyosumi Takaishi, Takao Shoji, Yoshiyuki Onishi, Yoshito Kanazawa, Makoto Koizumi, Yasuko Tomono, Aki Sugano, Akemi Shono, Shogo Minamikawa, China Nagano, Nana Sakakibara, Shinya Ishiko, Yuya Aoto, Misato Kamura, Yutaka Harita, Kenichiro Miura, Shoichiro Kanda, Naoya Morisada, Rini Rossanti, Ming Juan Ye, Yoshimi Nozu, Masafumi Matsuo, Hirofumi Kai, Kazumoto Iijima, Kandai Nozu
Publikováno v:
Nature Communications, Vol 11, Iss 1, Pp 1-8 (2020)
Alport syndrome is a progressive inherited nephritis accompanied by sensorineural loss of hearing and ocular abnormalities, for which there is currently no effective therapy. Here, the authors develop an exon-skipping therapy using an antisense-oligo
Externí odkaz:
https://doaj.org/article/165df2dbd3f44073aaae13fc966489b5
Autor:
Kenji Sugawara, Kazuhiro Nomura, Yuko Okada, Aki Sugano, Masaaki Matsumoto, Toru Takarada, Atsuko Takeuchi, Hiroyuki Awano, Yushi Hirota, Hisahide Nishio, Yutaka Takaoka, Wataru Ogawa
Publikováno v:
Journal of Diabetes Investigation, Vol 10, Iss 3, Pp 680-684 (2019)
Abstract Mutations of the hepatocyte nuclear factor 4α (HNF4α) gene give rise to maturity‐onset diabetes of the young type 1. Although many such mutations have been identified in affected individuals, part of these mutations has been characterize
Externí odkaz:
https://doaj.org/article/70dab074f4e34bc998d9513fc7ca9a37
Autor:
Aki Sugano, Yutaka Takaoka, Haruyuki Kataguchi, Mika Ohta, Shigemi Kimura, Masatake Araki, Yoshitomo Morinaga, Yoshihiro Yamamoto
Publikováno v:
Microorganisms, Vol 10, Iss 10, p 2090 (2022)
Previously, we developed a mathematical model via molecular simulation analysis to predict the infectivity of six SARS-CoV-2 variants. In this report, we aimed to predict the relative risk of the recent new variants of SARS-CoV-2 based on our previou
Externí odkaz:
https://doaj.org/article/0024f18bd8a745ac97e5fa2fe8dfb9b3
Autor:
Yutaka Takaoka, Mika Ohta, Satoshi Tateishi, Aki Sugano, Eiji Nakano, Kenji Miura, Takashi Suzuki, Chikako Nishigori
Publikováno v:
Biomedicines, Vol 9, Iss 3, p 249 (2021)
Xeroderma pigmentosum complementation group D (XPD) is a UV-sensitive syndrome and a rare incurable genetic disease which is caused by the genetic mutation of the excision repair cross-complementation group 2 gene (ERCC2). Patients who harbor only XP
Externí odkaz:
https://doaj.org/article/d519288b3295445da882cc5d8cfd204d
Establishment of the experimental procedure for prediction of conjugation capacity in mutant UGT1A1.
Autor:
Yutaka Takaoka, Atsuko Takeuchi, Aki Sugano, Kenji Miura, Mika Ohta, Takashi Suzuki, Daisuke Kobayashi, Takuji Kimura, Juichi Sato, Nobutaro Ban, Hisahide Nishio, Toshiyuki Sakaeda
Publikováno v:
PLoS ONE, Vol 14, Iss 11, p e0225244 (2019)
UDP-glucuronosyltransferase 1A1 (UGT1A1) is an enzyme that is found in the endoplasmic reticulum membrane and can reportedly have a large number of amino acid substitutions that result in the reduction of glucuronidation capacity. For example, advers
Externí odkaz:
https://doaj.org/article/5c987badd56346a1b30ffdc27ddf910c
Autor:
Aki Sugano, Haruyuki Kataguchi, Mika Ohta, Yoshiaki Someya, Shigemi Kimura, Yoshimasa Maniwa, Toshihide Tabata, Yutaka Takaoka
In this research, we aimed to predict the relative risk of the recent new variants of severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) on the basis of our previous research. We first performed molecular docking simulation analyses of the
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::9acfe84ff02e6f3ea109b3a61ba8db88
https://doi.org/10.1101/2023.01.18.524660
https://doi.org/10.1101/2023.01.18.524660
Autor:
Aki Sugano, Yutaka Takaoka, Haruyuki Kataguchi, Minoru Kumaoka, Mika Ohta, Shigemi Kimura, Masatake Araki, Yoshitomo Morinaga, Yoshihiro Yamamoto
ObjectivesIn our previous research, we developed a mathematical model via molecular simulation analysis to predict the infectivity of seven SARS-CoV-2 variants. In this report, we aimed to predict the relative risk of the recent new variants of SARS-
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::bf1ac20d0d97377871c78d4f058c9047
https://doi.org/10.1101/2022.08.25.505217
https://doi.org/10.1101/2022.08.25.505217
Publikováno v:
PLoS ONE, Vol 12, Iss 11, p e0188407 (2017)
Interleukin-13 (IL-13) is associated with allergic airway inflammation and airway remodeling. Our group found a variant with a single nucleotide polymorphism in the IL13 gene at position +2044G>A (rs20541) that was expected to result in the non-conse
Externí odkaz:
https://doaj.org/article/d59f84fe9dfe44718c09e208004e8de8
Publikováno v:
JAPANESE JOURNAL OF GYNECOLOGIC AND OBSTETRIC ENDOSCOPY. 37:112-116
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::0fc7f9ef61688c9de8ad51f43ef592ca
https://doi.org/10.5180/jsgoe.37.1_112
https://doi.org/10.5180/jsgoe.37.1_112
Autor:
Satoshi Yamashita, Kensaku Mori, Shintaro Oyama, Yoshimune Shiratori, Keiko Yamashita, Naoki Ishiguro, Daisuke Kobayashi, Aki Sugano, Chiaki Funada, Kikue Sato, Taiki Furukawa, Tomohiro Otani
Publikováno v:
Journal of the American Medical Informatics Association : JAMIA
Purpose Location visualization is essential for locating people/objects, improving efficiency, and preventing accidents. In hospitals, Wi-Fi, Bluetooth low energy (BLE) Beacon, indoor messaging system, and similar methods have generally been used for
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a76bac19431304fafe36ae3f45cfdd6d
https://doi.org/10.1093/jamia/ocaa204
https://doi.org/10.1093/jamia/ocaa204