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Bacterial symbionts of insect pathogenic nematodes of the families Steinernematidae and Heterorhabditidae

Autor: Akhurst, RJ

Insect pathogenic nematodes of the families Steinermatidae and Heterorhabditidae from 42 populations (four, genera and over nine species) from Australasia, Europe and North America were found to be symbiotically associated with bacteria of the genus

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::bfe7bf966f2fbc50ad2083be5e74afed

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A study of the free-living phase of Deladenus, nematodes parasitic in woodwasps

Autor: Akhurst, RJ

1. Two populations of D. siricidicoZa and one of D. rudyi which had been maintained continuously in monoxenic culture for 1 year (D. siricidicoZa (S), D. rudyi (T)) and 6 years (D. siricidicoZa (H)) were used to study the effects of a range of enviro

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::185f12f4d22e0654f2e70b816756c350

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Genetic polymorphism in Methylenetetrahydrofolate Reductase chloride transport protein 6 (MTHFR CLCN6) gene is associated with keratinocyte skin cancer in a cohort of renal transplant recipients

Autor: Griffin, L, Ho, L, Akhurst, RJ, Arron, ST, Boggs, JME, Conlon, P, O'Kelly, P, Toland, AE, Epstein, EH, Balmain, A, Bastian, BC, Moloney, FJ, Murphy, GM, Laing, ME

Publikováno v: Skin health and disease, vol 2, iss 2

BackgroundRenal transplant recipients (RTRs) are at increased risk of keratinocyte cancer (KC), especially cutaneous squamous cell carcinoma (cSCC). Previous studies identified a genetic variant of the Methylenetetrahydrofolate Reductase (MTHFR) gene

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=od_______325::598e5ce946c1b01f1d20790fdaf2026e
https://escholarship.org/uc/item/43c8z3rt

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ShcA Protects against Epithelial–Mesenchymal Transition through Compartmentalized Inhibition of TGF-β-Induced Smad Activation

Autor: Akhurst, Rosemary, Muthusamy, BP, Budi, EH, Katsuno, Y, Lee, MK, Smith, SM, Mirza, AM, Akhurst, RJ, Derynck, R

Publikováno v: Akhurst, Rosemary; Muthusamy, BP; Budi, EH; Katsuno, Y; Lee, MK; Smith, SM; et al.(2015). ShcA Protects against Epithelial–Mesenchymal Transition through Compartmentalized Inhibition of TGF-β-Induced Smad Activation. UC San Francisco: Retrieved from: http://www.escholarship.org/uc/item/9hb7d04r

© 2015 Muthusamy et al.Epithelial–mesenchymal transition (EMT) is a normal cell differentiation event during development and contributes pathologically to carcinoma and fibrosis progression. EMT often associates with increased transforming growth

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=od_______325::a363037defa8dcc77a86027d86b1e882
http://www.escholarship.org/uc/item/9hb7d04r

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Complexities of TGF-β targeted cancer therapy

Autor: Akhurst, Rosemary, Connolly, EC, Freimuth, J, Akhurst, RJ

Publikováno v: Akhurst, Rosemary; Connolly, EC; Freimuth, J; & Akhurst, RJ. (2012). Complexities of TGF-β targeted cancer therapy.. UC San Francisco: Retrieved from: http://www.escholarship.org/uc/item/12n3m9v6

Many advanced tumors produce excessive amounts of Transforming Growth Factor-β (TGF-β) which, in normal epithelial cells, is a potent growth inhibitor. However, in oncogenically activated cells, the homeostatic action of TGF-β is often diverted al

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=od_______325::a637015ad7a6249cf22e2d5130774cd6
http://www.escholarship.org/uc/item/12n3m9v6

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Erratum: Targeting the TGFβ signalling pathway in disease (Nature Reviews Drug Discovery (2012) 11 (790-811))

Autor: Akhurst, RJ, Hata, A

Publikováno v: Nature Reviews Drug Discovery, vol 11, iss 11
Akhurst, RJ; & Hata, A. (2012). Erratum: Targeting the TGFβ signalling pathway in disease (Nature Reviews Drug Discovery (2012) 11 (790-811)). Nature Reviews Drug Discovery, 11(11), 886. doi: 10.1038/nrd3878. UCSF: Retrieved from: http://www.escholarship.org/uc/item/77w4h5ww

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=dedup_wf_001::397380d42bdcbb13e5ac9fa43f4d4d4b
https://escholarship.org/uc/item/77w4h5ww

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