Zobrazeno 1 - 10
of 29
pro vyhledávání: '"Akhlesh Kumar Jain"'
Publikováno v:
Current Pharmaceutical Design. 29:1026-1045
Abstract: Microsponges are polymeric delivery devices composed of porous microspheres that range in size from 5 to 300 micrometers. These have been explored for biomedical applications such as targeted drug delivery, transdermal drug delivery, antica
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::58a461ba90bb4d1cba29d80544126709
https://doi.org/10.2174/1381612829666230404082743
https://doi.org/10.2174/1381612829666230404082743
Publikováno v:
Current Pharmaceutical Design. 29:79-94
Abstract: About 2.8% of the global population are being suffered from Diabetes mellitus. Diabetes mellitus is a group of metabolic disorders that is characterized by an absolute lack of insulin and resulting in hyperglycemia. To overcome the challeng
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::8324e9fcd31cdab2777b12bd0a8f9b93
https://doi.org/10.2174/1381612829666221220115649
https://doi.org/10.2174/1381612829666221220115649
Autor:
Avadh Biharee, Arpita Yadav, Kailash Jangid, Yogesh Singh, Swanand Kulkarni, Devesh M. Sawant, Pradeep Kumar, Suresh Thareja, Akhlesh Kumar Jain
Publikováno v:
Journal of Biomolecular Structure and Dynamics. :1-12
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::d0ef4453e0552941823eeccdb8ed9699
https://doi.org/10.1080/07391102.2022.2126397
https://doi.org/10.1080/07391102.2022.2126397
Publikováno v:
Current Drug Delivery. 19:93-103
Introduction: Metformin, an anti-diabetic drug, has low bioavailability and short biological half-life. Thus, bioavailability enhancement and prolonged release of the drug are highly desirable. In this regard, we aimed to developed gastroretentive na
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::89171d8516a8721288477aa3049e8097
https://doi.org/10.2174/1567201818666210614095159
https://doi.org/10.2174/1567201818666210614095159
Autor:
Laxmi Banjare, Yogesh Singh, Sant Kumar Verma, Atul Kumar Singh, Pradeep Kumar, Shashank Kumar, Akhlesh Kumar Jain, Suresh Thareja
Publikováno v:
Journal of Biomolecular Structure and Dynamics. 41:1322-1341
Aromatase, a cytochrome P450 enzyme, is responsible for the conversion of androgens to estrogens, which fuel the multiplication of cancerous cells. Inhibition of estrogen biosynthesis by aromatase inhibitors (AIs) is one of the highly advanced therap
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::6ad20d03c1efafe20a6b5d3ad0f491f9
https://doi.org/10.1080/07391102.2021.2019122
https://doi.org/10.1080/07391102.2021.2019122
Publikováno v:
Mini-Reviews in Medicinal Chemistry. 21:3144-3165
Abstract: Breast cancer is the most frequent diagnosed cancer in women and the second most common form of cancer, causing death after lung cancer, all across the globe at an alarming rate. The level of estrogens, in breast cancer tissues of postmenop
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::62296812badd2d03f94f1555de50eb97
https://doi.org/10.2174/1389557521666210119123840
https://doi.org/10.2174/1389557521666210119123840
Autor:
Avadh, Biharee, Arpita, Yadav, Kailash, Jangid, Yogesh, Singh, Swanand, Kulkarni, Devesh M, Sawant, Pradeep, Kumar, Suresh, Thareja, Akhlesh Kumar, Jain
Publikováno v:
Journal of biomolecular structuredynamics.
Cancer is one of the most concerning diseases to humankind. Various treatment strategies are being employed for its treatment, out of which use of natural products is an essential one. Flavonoids have proven to be promising anticancer targets since d
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::f50340b77be5848b8c2f5dd3685542d4
https://pubmed.ncbi.nlm.nih.gov/36165610
https://pubmed.ncbi.nlm.nih.gov/36165610
Autor:
Sant Kumar Verma, Seema Mandavi, Akhlesh Kumar Jain, Amit Dubey, Renu Bhatt, Laxmi Banjare, Suresh Thareja
Publikováno v:
Medicinal Chemistry. 17:611-622
Aim The present research aims to insight into target binding and mapping of spatial fingerprints of noscapinoids as inhibitors of tubulin. Background Owing to its potential to interfere in microtubule dynamics in mitotic phase of cell cycle and selec
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d596b9a33396de12f1b2ffdfd646f0af
https://doi.org/10.2174/1573406416666200117120348
https://doi.org/10.2174/1573406416666200117120348
Autor:
Akhlesh Kumar Jain, Keerti Mishra
Publikováno v:
Current Pharmaceutical Design. 27:2398-2414
Background: Conventional drug delivery agents for a life-threatening disease, i.e., cancer, lack specificity towards cancer cells, producing a greater degree of side effects in the normal cells with a poor therapeutic index. These toxic side effects
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::8b60a47e6a2b5bc5b0bbdf86c69607fa
https://doi.org/10.2174/1381612827666210406141449
https://doi.org/10.2174/1381612827666210406141449
Publikováno v:
Current Drug Delivery. 18:369-380
Aim: To design D-Mannose conjugated 5-Fluorouracil (5-FU) loaded Jackfruit Seed Starch Nanoparticles (JFSSNPs) for site-specific delivery. Background: Liver cancer is the third leading cause of death in the world and the fifth most often diagnosed ca
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::aa3e8b10dcc7e044c4706d17d6544f5a
https://doi.org/10.2174/1567201817666200903171124
https://doi.org/10.2174/1567201817666200903171124