Zobrazeno 1 - 4
of 4
pro vyhledávání: '"Akhil Upad"'
Publikováno v:
Protein & Cell, Vol 11, Iss 6, Pp 401-416 (2020)
Abstract Epigenetic modifications, including those on DNA and histones, have been shown to regulate cellular metabolism by controlling expression of enzymes involved in the corresponding metabolic pathways. In turn, metabolic flux influences epigenet
Externí odkaz:
https://doaj.org/article/350d58bb43bc427e893cd6482c0b69f7
Autor:
Qingfei Zheng, Ryan M. Bastle, Shuai Zhao, Lingchun Kong, Lauren Vostal, Aarthi Ramakrishnan, Li Shen, Sasha L. Fulton, Haifeng Wang, Baichao Zhang, Akhil Upad, Robert E. Thompson, Henrik Molina, Stephanie Stransky, Simone Sidoli, Tom W. Muir, Haitao Li, Yael David, Ian Maze
Histone H3 monoaminylations at glutamine(Q) 5 represent an important family of epigenetic markers in neurons that play critical roles in the mediation of permissive gene expression (1, 2). We previously demonstrated that H3Q5 serotonylation(ser) and
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::39f4bcd087bc9641bf57dddcc13738e2
https://doi.org/10.1101/2022.12.06.519310
https://doi.org/10.1101/2022.12.06.519310
Publikováno v:
Protein & Cell, Vol 11, Iss 6, Pp 401-416 (2020)
Protein & Cell
Protein & Cell
Epigenetic modifications, including those on DNA and histones, have been shown to regulate cellular metabolism by controlling expression of enzymes involved in the corresponding metabolic pathways. In turn, metabolic flux influences epigenetic regula
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::5bc99fe6d9fc692ac35d4e73183466fd
https://doi.org/10.1007/s13238-020-00722-w
https://doi.org/10.1007/s13238-020-00722-w
Publikováno v:
J Org Chem
Methylglyoxal (MGO) is a reactive dicarbonyl metabolite that modifies histones in vivo and induces changes in chromatin structure and function. Here we report the synthesis and application of a chemical probe for investigating MGO-glycation. A two-st
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::fc4e65d1391c36cae161cd51ba318b8f
https://doi.org/10.1021/acs.joc.9b02504
https://doi.org/10.1021/acs.joc.9b02504