Zobrazeno 1 - 10
of 140
pro vyhledávání: '"Akhil Bidani"'
Publikováno v:
Journal of Theoretical Biology. 244:190-207
This paper presents a novel multiscale methodology for quantitative analysis of pulmonary gas exchange. The process of oxygen uptake in the lungs is a complex multiscale process, characterized by multiple time and length scales which are coupled nonl
Autor:
Lisa Y. Armitige, Mark B. Snuggs, Akhil Bidani, Subramanian Dhandayuthapani, Chinnaswamy Jagannath, Rachel A. Moulton, Robert L. Hunter, Christopher R. Singh
Publikováno v:
The Journal of Immunology. 177:3250-3259
Mycobacterium tuberculosis (strain H37Rv) and bacillus Calmette-Guérin (BCG) vaccine inhibit phagosome maturation in macrophages and their effect on processing, and presentation of a secreted Ag85 complex B protein, Ag85B, by mouse macrophages was
Publikováno v:
IEEE Transactions on Neural Systems and Rehabilitation Engineering. 13:120-124
We have developed a model of the mammalian respiratory central pattern generator (rCPG) to mimic the salient characteristics of its constituent medullary neurons. This model is designed as a network of Hodgkin-Huxley-type medullary neurons driven by
Publikováno v:
IEEE Transactions on Nanobioscience. 3:257-264
An analytical model of V-type H/sup +/-translocating ATPase (V-ATPase) was developed based on an approximation to the mechanochemical model of Grabe et al. (Biophys. J., pp. 2798-2813, vol. 78, 2000). Grabe's work utilizes structural information and
Publikováno v:
Journal of Applied Physiology. 97:2284-2302
This paper presents an analytical expression for the diffusing capacity (Θt) of the red blood cell (RBC) for any reactive gas in terms of size and shape of the RBC, thickness of the unstirred plasma layer surrounding the RBC, diffusivities and solub
Autor:
Akhil Bidani, Thomas A. Heming
Publikováno v:
Lung. 181:121-135
The acid-base status and functional responses of alveolar macrophages (mphi) are influenced by the activity of plasmalemmal V-type H+-pump (V-ATPase), an electrogenic H+ extruder that provides a possible link between intracellular pH (pHi) and plasma
Autor:
Jason B. Jayroe, Donald J. Deyo, Dongfang Wang, Joseph B. Zwischenberger, Scott K. Alpard, Akhil Bidani
Publikováno v:
ASAIO Journal. 49:30-34
Arteriovenous carbon dioxide removal (AVCO2R) as an alternative treatment for acute respiratory distress syndrome uses a low resistance gas exchanger in a simple arteriovenous shunt to achieve total CO2 removal and allow lung rest. We have previously
Autor:
Thomas A. Heming, Akhil Bidani
Publikováno v:
Immunobiology. 207:141-148
The role of plasmalemmal V-type H+ translocating ATPase (V-ATPase) in regulation of intracellular pH (pHi) is unclear in monocytes. This study examined the plasmalemmal V-ATPase and Na+/H+ exchanger (NHE) in U937 human monocytes. The fluorescent prob
Publikováno v:
Cardiovascular Engineering: An International Journal. 3:1-19
We have developed a closed-loop model of whole-body human gas exchange to simulate apnea and apneic oxygenation and have included it in our previously developed model of the human cardiopulmonary (CP) system. In our previous CP model, gas exchange oc
Publikováno v:
Clinical Science. 103:567-575
Aquaporins (AQs) increase cell membrane CO(2) diffusivity, and it has been proposed that they may serve as transmembrane channels for CO(2) and other small gas molecules. In addition, it has been hypothesized that voltage-gated H(+) channels located