Zobrazeno 1 - 10
of 40
pro vyhledávání: '"Akhil, Varshney"'
Autor:
Shruti Rathore, Aman Verma, Ria Ratna, Navjot Marwa, Yagya Ghiya, Santosh G Honavar, Anil Tiwari, Sima Das, Akhil Varshney
Publikováno v:
Indian Journal of Ophthalmology, Vol 71, Iss 7, Pp 2662-2676 (2023)
Retinoblastoma is a retinal cancer that affects children and is the most prevalent intraocular tumor worldwide. Despite tremendous breakthroughs in our understanding of the fundamental mechanisms that regulate progression of retinoblastoma, the devel
Externí odkaz:
https://doaj.org/article/ece9e98f696e4d49866e6ed36c743d36
Autor:
Nidhi Gupta, Maninder Bhogal, Pravin K Vaddavalli, Alessandro Boldini, Francesco Semeraro, Akhil Varshney, Vito Romano
Publikováno v:
Indian Journal of Ophthalmology, Vol 71, Iss 5, Pp 2230-2233 (2023)
Here we describe a new, non-human, ex-vivo model (goat eye model) for training surgeons in DMEK surgeons. In a wet lab setting, goat eyes were used to obtain a pseudo-DMEK graft of 8 mm from the goat lens capsule that was injected into another goat e
Externí odkaz:
https://doaj.org/article/b68f7ed8a2e7429a8052b447a24aa1b7
Autor:
Sima Das, Akhil Varshney
Publikováno v:
Indian Journal of Ophthalmology, Vol 71, Iss 2, Pp 432-433 (2023)
Externí odkaz:
https://doaj.org/article/e44505bd00eb4f7482861732fb2c29ea
Autor:
Balamurali K. Ambati, Akhil Varshney, Kenneth Lundstrom, Giorgio Palú, Bruce D. Uhal, Vladimir N. Uversky, Adam M. Brufsky
Publikováno v:
Frontiers in Virology, Vol 2 (2022)
Externí odkaz:
https://doaj.org/article/e8ad1abce0214d3ab7e670974a380428
Autor:
Siddharth Narendran, Felipe Pereira, Praveen Yerramothu, Ivana Apicella, Shao-bin Wang, Kameshwari Ambati, Shuichiro Hirahara, Younghee Kim, Meenakshi Ambati, Vidya L. Ambati, Peirong Huang, Akhil Varshney, Yosuke Nagasaka, Shinichi Fukuda, Kirstie L. Baker, Kenneth M. Marion, Jan M. Deussing, Srinivas R. Sadda, Bradley D. Gelfand, Jayakrishna Ambati
Publikováno v:
Signal Transduction and Targeted Therapy, Vol 6, Iss 1, Pp 1-9 (2021)
Abstract Nonfibrillar amyloid-β oligomers (AβOs) are a major component of drusen, the sub-retinal pigmented epithelium (RPE) extracellular deposits characteristic of age-related macular degeneration (AMD), a common cause of global blindness. We rep
Externí odkaz:
https://doaj.org/article/3b63bb9d0ace4f3fbe816152ffbe4d39
Autor:
Jayakrishna Ambati, Joseph Magagnoli, Hannah Leung, Shao-bin Wang, Chris A. Andrews, Dongxu Fu, Akshat Pandey, Srabani Sahu, Siddharth Narendran, Shuichiro Hirahara, Shinichi Fukuda, Jian Sun, Lekha Pandya, Meenakshi Ambati, Felipe Pereira, Akhil Varshney, Tammy Cummings, James W. Hardin, Babatunde Edun, Charles L. Bennett, Kameshwari Ambati, Benjamin J. Fowler, Nagaraj Kerur, Christian Röver, Norbert Leitinger, Brian C. Werner, Joshua D. Stein, S. Scott Sutton, Bradley D. Gelfand
Publikováno v:
Nature Communications, Vol 11, Iss 1, Pp 1-12 (2020)
Inflammasome activation may contribute to type 2 diabetes, but whether targeting inflammasome is beneficial is unclear. Here the authors show that repurposing nucleoside reverse transcriptase inhibitors for inhibiting inflammasome activation is assoc
Externí odkaz:
https://doaj.org/article/3c663125a9b94db7a11c2309f51581c5
Autor:
Balamurali K. Ambati, Akhil Varshney, Kenneth Lundstrom, Giorgio Palú, Bruce D. Uhal, Vladimir N. Uversky, Adam M. Brufsky
Publikováno v:
Frontiers in Virology, Vol 2 (2022)
Among numerous point mutation differences between the SARS-CoV-2 and the bat RaTG13 coronavirus, only the 12-nucleotide furin cleavage site (FCS) exceeds 3 nucleotides. A BLAST search revealed that a 19 nucleotide portion of the SARS-CoV-2 genome enc
Externí odkaz:
https://doaj.org/article/69725fd0c98f4969a77f29fda8d21271
Autor:
Sudhir Verma, Aastha Singh, Akhil Varshney, R. Arun Chandru, Manisha Acharya, Jyoti Rajput, Virender Singh Sangwan, Amit K. Tiwari, Tuhin Bhowmick, Anil Tiwari
Publikováno v:
Frontiers in Immunology, Vol 12 (2021)
Epigenetic mechanisms modulate gene expression and function without altering the base sequence of DNA. These reversible, heritable, and environment-influenced mechanisms generate various cell types during development and orchestrate the cellular resp
Externí odkaz:
https://doaj.org/article/e3c5379e5b4b435f9033c62d36bc5723
Autor:
Nidhi Gupta, Akhil Varshney, Muralidhar Ramappa, Sayan Basu, Vito Romano, Manisha Acharya, Abha Gaur, Neha Kapur, Aastha Singh, Gaurav Shah, Isha Chaudhary, Nikunj Patel, Anil Tiwari, Anahita Kate, Virender Sangwan, Umang Mathur
Publikováno v:
Diagnostics, Vol 12, Iss 4, p 918 (2022)
Optical coherence tomography (OCT) is analogous to ultrasound biometry in the cross sectional imaging of ocular tissues. Development of current devices with deeper penetration and higher resolution has made it popular tool in clinics for visualizatio
Externí odkaz:
https://doaj.org/article/949cb0c782514e859fff276b9aa1a8d2
Autor:
Vidya L. Ambati, Ivana Apicella, Srinivas R. Sadda, Peirong Huang, Akhil Varshney, Nagaraj Kerur, Shaobin Wang, Meenakshi Ambati, Felipe Pereira, Siddharth Narendran, Kameshwari Ambati, Kirstie Baker, Yosuke Nagasaka, Dionne Argyle, Bo Liu, Bradley D. Gelfand, Kenneth M. Marion, Tamer Sallam, Scott W. Canna, Kartik Gupta, Praveen Yerramothu, Jayakrishna Ambati, Shuichiro Hirahara, David R. Hinton
Publikováno v:
Science Immunology. 6
Detection of microbial products by multiprotein complexes known as inflammasomes is pivotal to host defense against pathogens. Nucleotide-binding domain leucine-rich repeat (NLR) CARD domain containing 4 (NLRC4) forms an inflammasome in response to b
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b9dae64677cc0a97a7ae747b43001eab
https://doi.org/10.1126/sciimmunol.abi4493
https://doi.org/10.1126/sciimmunol.abi4493