Inceptor binds to and directs insulin towards lysosomal degradation in β cells.

Autor: Siehler J; Institute of Diabetes and Regeneration Research, Helmholtz Diabetes Center, Helmholtz Zentrum München, Neuherberg, Germany.; German Center for Diabetes Research (DZD), Neuherberg, Germany.; School of Medicine and Health, Technische Universität München, Munich, Germany., Bilekova S; Institute of Diabetes and Regeneration Research, Helmholtz Diabetes Center, Helmholtz Zentrum München, Neuherberg, Germany.; German Center for Diabetes Research (DZD), Neuherberg, Germany.; School of Medicine and Health, Technische Universität München, Munich, Germany., Chapouton P; Institute of Diabetes and Regeneration Research, Helmholtz Diabetes Center, Helmholtz Zentrum München, Neuherberg, Germany.; German Center for Diabetes Research (DZD), Neuherberg, Germany., Dema A; Institute of Diabetes and Regeneration Research, Helmholtz Diabetes Center, Helmholtz Zentrum München, Neuherberg, Germany.; German Center for Diabetes Research (DZD), Neuherberg, Germany., Albanese P; Biomolecular Mass Spectrometry and Proteomics, Bijvoet Center for Biomolecular Research, Utrecht University, Utrecht, The Netherlands.; Utrecht Institute for Pharmaceutical Sciences, Utrecht University, Utrecht, Netherlands.; Proteomics Centre, Utrecht, The Netherlands.; Université Grenoble Alpes, IRIG, CEA, CNRS, INRAE, UMR 5168, 38000, Grenoble, France.; Université Grenoble Alpes, INSERM, IRIG, CEA, UA13 BGE, CNRS, CEA, FR2048 ProFI, 38000, Grenoble, France., Tamara S; Biomolecular Mass Spectrometry and Proteomics, Bijvoet Center for Biomolecular Research, Utrecht University, Utrecht, The Netherlands.; Utrecht Institute for Pharmaceutical Sciences, Utrecht University, Utrecht, Netherlands.; Proteomics Centre, Utrecht, The Netherlands., Jain C; Institute of Diabetes and Regeneration Research, Helmholtz Diabetes Center, Helmholtz Zentrum München, Neuherberg, Germany.; German Center for Diabetes Research (DZD), Neuherberg, Germany., Sterr M; Institute of Diabetes and Regeneration Research, Helmholtz Diabetes Center, Helmholtz Zentrum München, Neuherberg, Germany.; German Center for Diabetes Research (DZD), Neuherberg, Germany., Enos SJ; German Center for Diabetes Research (DZD), Neuherberg, Germany.; Institute of Physiology, Faculty of Medicine Carl Gustav Carus, Dresden University of Technology, Dresden, Germany.; Paul Langerhans Institute Dresden (PLID) of the Helmholtz Zentrum München at the University Clinic Carl Gustav Carus of Dresden University of Technology, Dresden, Germany., Chen C; German Center for Diabetes Research (DZD), Neuherberg, Germany.; Institute of Physiology, Faculty of Medicine Carl Gustav Carus, Dresden University of Technology, Dresden, Germany.; Paul Langerhans Institute Dresden (PLID) of the Helmholtz Zentrum München at the University Clinic Carl Gustav Carus of Dresden University of Technology, Dresden, Germany., Malhotra C; Institute of Diabetes and Regeneration Research, Helmholtz Diabetes Center, Helmholtz Zentrum München, Neuherberg, Germany.; TUM School of Life Sciences, Technische Universität München, Freising, Germany., Villalba A; Université Paris Cité, Institut Cochin, CNRS, INSERM, Paris, France., Schomann L; Institute of Diabetes and Regeneration Research, Helmholtz Diabetes Center, Helmholtz Zentrum München, Neuherberg, Germany.; German Center for Diabetes Research (DZD), Neuherberg, Germany.; School of Medicine and Health, Technische Universität München, Munich, Germany., Bhattacharya S; Institute of Diabetes and Regeneration Research, Helmholtz Diabetes Center, Helmholtz Zentrum München, Neuherberg, Germany.; German Center for Diabetes Research (DZD), Neuherberg, Germany.; School of Medicine and Health, Technische Universität München, Munich, Germany., Feng J; Institute of Diabetes and Regeneration Research, Helmholtz Diabetes Center, Helmholtz Zentrum München, Neuherberg, Germany.; German Center for Diabetes Research (DZD), Neuherberg, Germany.; School of Medicine and Health, Technische Universität München, Munich, Germany., Akgün Canan M; Institute of Diabetes and Regeneration Research, Helmholtz Diabetes Center, Helmholtz Zentrum München, Neuherberg, Germany.; German Center for Diabetes Research (DZD), Neuherberg, Germany.; School of Medicine and Health, Technische Universität München, Munich, Germany., Ribaudo F; Institute of Diabetes and Regeneration Research, Helmholtz Diabetes Center, Helmholtz Zentrum München, Neuherberg, Germany.; German Center for Diabetes Research (DZD), Neuherberg, Germany., Ansarullah; Institute of Diabetes and Regeneration Research, Helmholtz Diabetes Center, Helmholtz Zentrum München, Neuherberg, Germany.; German Center for Diabetes Research (DZD), Neuherberg, Germany., Burtscher I; Institute of Diabetes and Regeneration Research, Helmholtz Diabetes Center, Helmholtz Zentrum München, Neuherberg, Germany.; German Center for Diabetes Research (DZD), Neuherberg, Germany., Ahlbrecht C; German Center for Diabetes Research (DZD), Neuherberg, Germany.; Institute for Medicinal Chemistry, Molecular Targets and Therapeutics Center, Helmholtz Zentrum München, Neuherberg, Germany.; Institute of Organic Chemistry (BMWZ) and Laboratory for Nano- and Quantum Engineering (LNQE), Center of Biomolecular Research, Leibniz, University Hannover, Hannover, Germany., Plettenburg O; German Center for Diabetes Research (DZD), Neuherberg, Germany.; Institute for Medicinal Chemistry, Molecular Targets and Therapeutics Center, Helmholtz Zentrum München, Neuherberg, Germany.; Institute of Organic Chemistry (BMWZ) and Laboratory for Nano- and Quantum Engineering (LNQE), Center of Biomolecular Research, Leibniz, University Hannover, Hannover, Germany.; Institute of Lung Health (ILH), Giessen, Germany., Kurth T; Center for Molecular and Cellular Bioengineering (CMCB), Technology Platform, Core Facility Electron Microscopy and Histology, Dresden University of Technology, Dresden, Germany., Scharfmann R; Université Paris Cité, Institut Cochin, CNRS, INSERM, Paris, France., Speier S; German Center for Diabetes Research (DZD), Neuherberg, Germany.; Institute of Physiology, Faculty of Medicine Carl Gustav Carus, Dresden University of Technology, Dresden, Germany.; Paul Langerhans Institute Dresden (PLID) of the Helmholtz Zentrum München at the University Clinic Carl Gustav Carus of Dresden University of Technology, Dresden, Germany., Scheltema RA; Biomolecular Mass Spectrometry and Proteomics, Bijvoet Center for Biomolecular Research, Utrecht University, Utrecht, The Netherlands.; Utrecht Institute for Pharmaceutical Sciences, Utrecht University, Utrecht, Netherlands.; Proteomics Centre, Utrecht, The Netherlands.; Center for Proteome, Research and Department of Biochemistry, University of Liverpool, Liverpool, UK., Lickert H; Institute of Diabetes and Regeneration Research, Helmholtz Diabetes Center, Helmholtz Zentrum München, Neuherberg, Germany. heiko.lickert@helmholtz-munich.de.; German Center for Diabetes Research (DZD), Neuherberg, Germany. heiko.lickert@helmholtz-munich.de.; School of Medicine and Health, Technische Universität München, Munich, Germany. heiko.lickert@helmholtz-munich.de.

Publikováno v: Nature metabolism [Nat Metab] 2024 Dec; Vol. 6 (12), pp. 2374-2390. Date of Electronic Publication: 2024 Nov 25.

Krankheit und Krankheitsmanagement

Autor: Kliegel, Matthias, Brom, Sarah Susanne, Melzer, Marlen, Akgün, Canan

Publikováno v: Angewandte Gerontologie: Interventionen für ein gutes Altern in 100 Schlüsselbegriffen

Krankheit im Alter zeichnet sich durch Multimorbidität und Chronizität aus. Demnach leiden ältere Erwachsene häufig an mehreren Erkrankungen, bei denen keine vollständige Heilung zu erwarten ist und die umfassende psychische Anpassungen sowie Ve

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=od______1400::8ae44805ae3cd0c75187146230f980ac
https://archive-ouverte.unige.ch/unige:98306

Prospective Memory Across Adolescence: The Effects of Age and Cue Focality.

Autor: Lijuan Wang¹, Altgassen, Mareike², Wei Liu³, Weirui Xiong¹, Akgün, Canan², Kliegel, Matthias² kliegel@psychologie.tu-dresden.de

Publikováno v: Developmental Psychology. Jan2011, Vol. 47 Issue 1, p226-232. 7p. 1 Chart, 1 Graph.