Zobrazeno 1 - 10
of 24
pro vyhledávání: '"Akey Krishna, Swaroop"'
Autor:
Chennu Manisha, Nagarjuna Palathoti, Jagdish Chand, Akey Krishna Swaroop, Jubie Selvaraj, B.R. Prashantha Kumar, Prisil Naveentha X, Brindha Durairaj, Antony Justin
Publikováno v:
Results in Chemistry, Vol 11, Iss , Pp 101766- (2024)
EAAT2, a glial protein that clears excess glutamate from synapses, regulates synaptic transmission, and prevents excitotoxicity in neurons is impaired by Aβ induced oxidative stress in neurodegenerative diseases like Alzheimer’s disease. Therefore
Externí odkaz:
https://doaj.org/article/40eeef45cb9647a2ace834ba494112c5
Autor:
Akey Krishna Swaroop, Chaitanya Motamarri Venkata Naga Lalitha, Meena Shanmugam, Gomathy Subramanian, Jawahar Natarajan, Jubie Selvaraj
Publikováno v:
Advanced Pharmaceutical Bulletin, Vol 12, Iss 4, Pp 712-729 (2022)
The concept of immunomodulation was proposed by Edward Jenner, while working on polio vaccine in 1796. Many of the autoimmune diseases such as rheumatoid arthritis, inflammatory bowel diseases, psoriatic arthritis and system lupus erythematosus, vira
Externí odkaz:
https://doaj.org/article/68d153855b254d72be3b0c19e619d57f
Autor:
Patnaik, Sunil Kumar, Ayyamperumal, Selvaraj, Jade, Dhananjay, Palathoti, Nagarjuna, Akey, Krishna Swaroop, Jupudi, Srikanth, Harrison, Michael A., Ponnambalam, Sreenivasan, MJ, Nanjan, MJN, Chandrasekar
Publikováno v:
Journal of Biomolecular Structure & Dynamics; July (late) 2024, Vol. 42 Issue 11, p5551-5574, 24p
Autor:
Selvaraj Jubie, Ayushi Kar, Balamurugan Paramasivam, Darshini Jayakumar, Akey Krishna Swaroop
Publikováno v:
Current Drug Research Reviews. 15:228-240
Abstract: Diabetes Mellitus (DM) is one of the highest contributors to global mortality, exceeding numbers of even the three major infectious diseases in the world, namely Tuberculosis, HIV AIDS, and Malaria. DM is characterised by increased serum le
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::e504f91312fc4cbea887df75a227fb0e
https://doi.org/10.2174/2589977515666230214101808
https://doi.org/10.2174/2589977515666230214101808
Autor:
M.J.N. Chandrasekar, Sunil Kumar Patnaik, Palathoti Nagarjuna, Deepthi Ramamurthi, Akey Krishna Swaroop
Publikováno v:
Mini-Reviews in Medicinal Chemistry. 22:2831-2846
Abstract: Cancer is one of the deadliest diseases involving dysregulated cell proliferation and has been the leading cause of death worldwide. The chemotherapeutic drugs currently used for treating cancer have serious drawbacks of non-specific toxici
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e1b7a7ac9723ef756f183cb6c09701e6
https://doi.org/10.2174/1389557522666220512152448
https://doi.org/10.2174/1389557522666220512152448
Autor:
Nagaraj, Selvaraj, Akey Krishna, Swaroop, Bala Sai Soujith, Nidamanuri, Rajesh R, Kumar, Jawahar, Natarajan, Jubie, Selvaraj
Publikováno v:
Current Drug Research Reviews. 14:116-131
Abstract: New drug development for a disease is a tedious, time-consuming, complex, and expensive process. Even if it is done, the chances for success of newly developed drugs are still very low. Modern reports state that repurposing the pre-existing
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::79f26f1bdb99646fdcc831ccd871a3f9
https://doi.org/10.2174/2589977514666220214120403
https://doi.org/10.2174/2589977514666220214120403
Akademický článek
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Akademický článek
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Repurposing of FDA Approved Drugs and Neuropep peptides as Anticancer Agents Against ErbB1 and ErbB2
Autor:
Sunil Kumar Patnaik, Akey Krishna Swaroop, Mudavath Ravi Naik, Jubie Selvaraj, Moola Joghee Nanjan Chandrasekar
Publikováno v:
Drug Research.
ErbB1 and ErbB2 are the most important biological targets in cancer drug discovery and development of dual inhibitors for the cancer therapy. FDA approved drugs and Neuropep peptides were used to fit into the ATP binding site of the tyrosine kinases;
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::2058b6400e766f57b5d3799fa3399ba1
https://doi.org/10.1055/a-2030-4078
https://doi.org/10.1055/a-2030-4078
Dual Modulation of IL-6 Pathway by Flavonoid Metal Complex as Immune Boosters for SARS-CoV-2 Therapy
Autor:
Akey Krishna Swaroop, Esakkimuthukumar M, Patnaik S.K, Vasanth P, Jeyaprakash M.R, Jawahar N, Jubie S
Publikováno v:
ECS Transactions. 107:9771-9779
It is observed that Cytokine Release Syndrome (CRS) is one of the major causes of the death of several COVID-19 patients. Though several cytokines are involved in CRS, IL-6 modulation plays a major role. We aim to develop new flavonoid metal complexe
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::83e30d3870fd02b5175d278cbfa0800b
https://doi.org/10.1149/10701.9771ecst
https://doi.org/10.1149/10701.9771ecst