Zobrazeno 1 - 10
of 390
pro vyhledávání: '"Akey Joshua M"'
Autor:
Bigham Abigail W, Mao Xianyun, Mei Rui, Brutsaert Tom, Wilson Megan J, Julian Colleen, Parra Esteban J, Akey Joshua M, Moore Lorna G, Shriver Mark D
Publikováno v:
Human Genomics, Vol 4, Iss 2, Pp 79-90 (2009)
Abstract High-altitude environments (>2,500 m) provide scientists with a natural laboratory to study the physiological and genetic effects of low ambient oxygen tension on human populations. One approach to understanding how life at high altitude has
Externí odkaz:
https://doaj.org/article/b4561bd41cb04939b4065fd9f98e5423
Autor:
Ronald James, Akey Joshua M
Publikováno v:
Human Genomics, Vol 2, Iss 2, Pp 113-125 (2005)
Abstract Natural selection, which can be defined as the differential contribution of genetic variants to future generations, is the driving force of Darwinian evolution. Identifying regions of the human genome that have been targets of natural select
Externí odkaz:
https://doaj.org/article/fe19e9fe546c461d88cfaee53224e1b8
Autor:
Shriver Mark D, Mei Rui, Parra Esteban J, Sonpar Vibhor, Halder Indrani, Tishkoff Sarah A, Schurr Theodore G, Zhadanov Sergev I, Osipova Ludmila P, Brutsaert Tom D, Friedlaender Jonathan, Jorde Lynn B, Watkins W Scott, Bamshad Michael J, Gutierrez Gerardo, Loi Halina, Matsuzaki Hajime, Kittles Rick A, Argyropoulos George, Fernandez Jose R, Akey Joshua M, Jones Keith W
Publikováno v:
Human Genomics, Vol 2, Iss 2, Pp 81-89 (2005)
Abstract Understanding the distribution of human genetic variation is an important foundation for research into the genetics of common diseases. Some of the alleles that modify common disease risk are themselves likely to be common and, thus, amenabl
Externí odkaz:
https://doaj.org/article/c6b7917520ca4d44acec2e245416e58b
Autor:
Shriver Mark D, Kennedy Giulia C, Parra Esteban J, Lawson Heather A, Sonpar Vibhor, Huang Jing, Akey Joshua M, Jones Keith W
Publikováno v:
Human Genomics, Vol 1, Iss 4, Pp 274-286 (2004)
Abstract Understanding the nature of evolutionary relationships among persons and populations is important for the efficient application of genome science to biomedical research. We have analysed 8,525 autosomal single nucleotide polymorphisms (SNPs)
Externí odkaz:
https://doaj.org/article/4015010453854ac3b935cc6974730436
Publikováno v:
BMC Genomics, Vol 12, Iss 1, p 414 (2011)
Abstract Background Structural variation contributes to the rich genetic and phenotypic diversity of the modern domestic dog, Canis lupus familiaris, although compared to other organisms, catalogs of canine copy number variants (CNVs) are poorly defi
Externí odkaz:
https://doaj.org/article/b6a4488961924324a592eae5e3f4d3b4
Publikováno v:
BMC Bioinformatics, Vol 9, Iss 1, p 244 (2008)
Abstract Background The combination of gene expression profiling with linkage analysis has become a powerful paradigm for mapping gene expression quantitative trait loci (eQTL). To date, most studies have searched for eQTL by analyzing gene expressio
Externí odkaz:
https://doaj.org/article/9b4de865bca0488784f06934eeaedc8e
Autor:
Schmid, Sarah M., Hoffman, Jessica M., Prescott, Jena, Ernst, Holley, Promislow, Daniel E. L., Akey, Joshua M., Benton, Brooke, Borenstein, Elhanan, Castelhano, Marta G., Coleman, Amanda E., Creevy, Kate E., Crowder, Kyle, Dunbar, Matthew D., Fajt, Virginia R., Fitzpatrick, Annette L., Jeffery, Unity, Jonlin, Erica C., Kaeberlein, Matt, Karlsson, Elinor K., Kerr, Kathleen F.
Publikováno v:
GeroScience; Dec2024, Vol. 46 Issue 6, p5395-5407, 13p
Autor:
Tucci, Serena, Vohr, Samuel H., McCoy, Rajiv C., Vernot, Benjamin, Robinson, Matthew R., Barbieri, Chiara, Nelson, Brad J., Fu, Wenqing, Purnomo, Gludhug A., Sudoyo, Herawati, Eichler, Evan E., Barbujani, Guido, Visscher, Peter M., Akey, Joshua M., Green, Richard E.
Publikováno v:
Science, 2018 Aug 01. 361(6401), 511-517.
Externí odkaz:
https://www.jstor.org/stable/26498104
Autor:
Vernot, Benjamin, Tucci, Serena, Kelso, Janet, Schraiber, Joshua G., Wolf, Aaron B., Gittelman, Rachel M., Dannemann, Michael, Grote, Steffi, McCoy, Rajiv C., Norton, Heather, Scheinfeldt, Laura B., Merriwether, David A., Koki, George, Friedlaender, Jonathan S., Wakefield, Jon, Pääbo, Svante, Akey, Joshua M.
Publikováno v:
Science, 2016 Apr 01. 352(6282), 235-239.
Externí odkaz:
http://www.jstor.org/stable/24744207
Autor:
Simonti, Corinne N., Vernot, Benjamin, Bastarache, Lisa, Bottinger, Erwin, Carrell, David S., Chisholm, Rex L., Crosslin, David R., Hebbring, Scott J., Jarvik, Gail P., Kullo, Iftikhar J., Li, Rongling, Pathak, Jyotishman, Ritchie, Marylyn D., Roden, Dan M., Verma, Shefali S., Tromp, Gerard, Prato, Jeffrey D., Bush, William S., Akey, Joshua M., Denny, Joshua C., Capra, John A.
Publikováno v:
Science, 2016 Feb 01. 351(6274), 737-741.
Externí odkaz:
http://www.jstor.org/stable/24742623