Zobrazeno 1 - 10
of 10
pro vyhledávání: '"Akesh, Sinha"'
Autor:
Darpan N. Pandya, Akesh Sinha, Hong Yuan, Lysette Mutkus, Kristina Stumpf, Frank C. Marini, Thaddeus J. Wadas
Publikováno v:
Molecules, Vol 25, Iss 16, p 3672 (2020)
Glioblastoma multiforme (GBM) is the most aggressive glioma of the primary central nervous system. Due to the lack of effective treatment options, the prognosis for patients remains bleak. Fibroblast activation protein alpha (FAP), a 170 kDa type II
Externí odkaz:
https://doaj.org/article/0ccd82dedc384283a9124199814e1c4a
Autor:
Cynthia S. Day, Akesh Sinha, Darpan N. Pandya, Jason S. Lewis, Kelly E. Henry, Thaddeus J. Wadas, Yusuf Menda, Thomas R. Dilling, Brandie M. Ehrmann, Nikunj Bhatt, Stephen A. Graves, Veronica L. Nagle
Publikováno v:
Inorganic Chemistry. 59:17473-17487
Over the last three decades, the chemistry of zirconium has facilitated antibody development and the clinical management of disease in the precision medicine era. Scientists have harnessed its reactivity, coordination chemistry, and nuclear chemistry
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::e26a9e81687ced33aeb8f87f549085aa
https://doi.org/10.1021/acs.inorgchem.0c02722
https://doi.org/10.1021/acs.inorgchem.0c02722
Autor:
Darpan N, Pandya, Kelly E, Henry, Cynthia S, Day, Stephen A, Graves, Veronica L, Nagle, Thomas R, Dilling, Akesh, Sinha, Brandie M, Ehrmann, Nikunj B, Bhatt, Yusuf, Menda, Jason S, Lewis, Thaddeus J, Wadas
Publikováno v:
Inorg Chem
Over the last three decades, the chemistry of zirconium has facilitated antibody development and the clinical management of disease in the precision medicine era. Scientists have harnessed its reactivity, coordination chemistry and nuclear chemistry
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::a324e7e412386e867c74b9e2ee656dce
https://pubmed.ncbi.nlm.nih.gov/33169605
https://pubmed.ncbi.nlm.nih.gov/33169605
Autor:
Caroline Köhrer, Akesh Sinha, Michael H.W. Weber, Isao Masuda, Uttam L. RajBhandary, Ya-Ming Hou, Vamsi K. Mootha
Publikováno v:
Journal of Biological Chemistry. 289:32729-32741
N-Formylation of initiator methionyl-tRNA (Met-tRNA(Met)) by methionyl-tRNA formyltransferase (MTF) is important for translation initiation in bacteria, mitochondria, and chloroplasts. Unlike all other translation systems, the metazoan mitochondrial
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f3174d635ce9cfdfacb73eb397959be8
https://doi.org/10.1074/jbc.m114.610626
https://doi.org/10.1074/jbc.m114.610626
Publikováno v:
Journal of Biological Chemistry. 285:34309-34318
The PhoP and PhoR proteins from Mycobacterium tuberculosis form a highly specific two-component system that controls expression of genes involved in complex lipid biosynthesis and regulation of unknown virulence determinants. The several functions of
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::a2e419dc9ee80297a118c40fcaa76f64
https://doi.org/10.1074/jbc.m110.135822
https://doi.org/10.1074/jbc.m110.135822
Publikováno v:
Journal of Bacteriology. 191:7466-7476
Mycobacterium tuberculosis PhoP of the PhoP-PhoR two-component signaling system orchestrates a complex transcription program and is essential for the growth and virulence of the tubercle bacillus. PhoP comprises a phosphorylation domain at the amino-
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f76ea5f6be54b9b726a767b194032550
https://doi.org/10.1128/jb.00669-09
https://doi.org/10.1128/jb.00669-09
Autor:
Subramanian Karthikeyan, Manish Datt, Akesh Sinha, Anuj Pathak, Arijit Kumar Das, Dibyendu Sarkar, Balvinder Singh
Publikováno v:
Journal of molecular biology. 398(5)
The Mycobacterium tuberculosis PhoP-PhoR two-component system is essential for virulence in animal models of tuberculosis. Genetic and biochemical studies indicate that PhoP regulates the expression of more than 110 genes in M. tuberculosis. The C-te
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::1ee862e2d3eb36efb2d98da4a5ec865e
https://pubmed.ncbi.nlm.nih.gov/20363229
https://pubmed.ncbi.nlm.nih.gov/20363229
Publikováno v:
Journal of bacteriology. 190(4)
Mycobacterium tuberculosis PhoP regulates the expression of unknown virulence determinants and the biosynthesis of complex lipids. PhoP, like other members of the OmpR family, comprises a phosphorylation domain at the amino-terminal half and a DNA-bi
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::4adaab2be284d0b2640c973728dce270
https://pubmed.ncbi.nlm.nih.gov/18065544
https://pubmed.ncbi.nlm.nih.gov/18065544
Publikováno v:
FEBS letters. 580(22)
The PhoP-PhoR two-component system is essential for virulence and intracellular growth of Mycobacterium tuberculosis (MTB) in human and mouse macrophages or in mice. Here, PhoP and truncated PhoR sensor proteins were shown to participate in phosphotr
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c61c648bd225fc972e3dbd8259a322d6
https://pubmed.ncbi.nlm.nih.gov/16979633
https://pubmed.ncbi.nlm.nih.gov/16979633
Autor:
Akesh Sinha1, Köhrer, Caroline1, Weber, Michael H. W.1, Isao Masuda2, Mootha, Vamsi K.3, Ya-Ming Hou2, RajBhandary, Uttam L.1 bhandary@mit.edu
Publikováno v:
Journal of Biological Chemistry. 11/21/2014, Vol. 289 Issue 47, p32729-32741. 13p.