Zobrazeno 1 - 10
of 19
pro vyhledávání: '"Akemi Toyoda"'
Autor:
Eri Sakamoto, Yasuhiro Katahira, Izuru Mizoguchi, Aruma Watanabe, Yuma Furusaka, Ami Sekine, Miu Yamagishi, Jukito Sonoda, Satomi Miyakawa, Shinya Inoue, Hideaki Hasegawa, Kazuyuki Yo, Fumiya Yamaji, Akemi Toyoda, Takayuki Yoshimoto
Publikováno v:
Biology, Vol 12, Iss 1, p 123 (2023)
Haptens are small molecules that only elicit an immune response when bound to proteins. Haptens initially bind to self-proteins and activate innate immune responses by complex mechanisms via inflammatory cytokines and damage-associated molecular patt
Externí odkaz:
https://doaj.org/article/54dce7ee5a3b4fbe9e89789209677a72
Autor:
Noriyasu, Imai, Midori, Takeyoshi, Sakiko, Aizawa, Mika, Tsurumaki, Masaharu, Kurosawa, Akemi, Toyoda, Maki, Sugiyama, Kaoru, Kasahara, Shinichi, Ogata, Takashi, Omori, Morihiko, Hirota
Publikováno v:
Journal of Applied Toxicology. 42:1029-1043
Demands for the elimination and replacement of animal experiments for cosmetic safety assessment have increased in recent years. Evaluation of skin sensitization, however, is a critical issue in cosmetic safety assessment. The SH test is an in vitro
Autor:
Maki Sugiyama, Morihiko Hirota, Midori Takeyoshi, Noriyasu Imai, Sakiko Aizawa, Masaharu Kurosawa, Kaoru Kasahara, Mika Tsurumaki, Akemi Toyoda, Shinichi Ogata
Publikováno v:
The Journal of Toxicological Sciences. 46:235-248
There has been an increased demand to eliminate animal experiments and to replace the experiments with alternative tests for assessing the safety of cosmetics. The SH test is an in vitro skin sensitization test that evaluates the protein binding abil
Autor:
Akemi Toyoda1,2 a-toyoda@pola.co.jp, Hiroshi Itagaki2
Publikováno v:
Journal of Toxicological Sciences. Aug2018, Vol. 43 Issue 4, p247-256. 10p.
Autor:
Noriyasu, Imai, Midori, Takeyoshi, Sakiko, Aizawa, Mika, Tsurumaki, Masaharu, Kurosawa, Akemi, Toyoda, Maki, Sugiyama, Kaoru, Kasahara, Morihiko, Hirota, Shinichi, Ogata
Publikováno v:
The Journal of toxicological sciences. 46(5)
There has been an increased demand to eliminate animal experiments and to replace the experiments with alternative tests for assessing the safety of cosmetics. The SH test is an in vitro skin sensitization test that evaluates the protein binding abil
Autor:
Kazuhiro Hosoi, Takao Ashikaga, Hiroshi Onodera, Hirokazu Kouzuki, Akemi Toyoda, Hajime Kojima, Satomi Onoue, Osamu Fueki
Publikováno v:
Yakugaku zasshi : Journal of the Pharmaceutical Society of Japan. 141(1)
Phototoxicity is a toxic response elicited by topically applied or systemically administered photoreactive chemicals after exposure to light and can be broadly categorized into photoirritation, photoallergy, photogenotoxicity, and photocarcinogenicit
Autor:
Daiki Kyotani, Hidenobu Okumura, Shigeyuki Nomura, Takashi Omori, Yuki Handa, Yuko Okamoto, Yasuo Ohno, Noriyasu Imai, Hiroaki Todo, Setsuko Jitsukawa, Masakazu Katoh, Hidefumi Ikeda, Kenji Sugibayashi, Shigenobu Hagino, Miyuki Fujishiro, Nathalie Alépée, Akemi Toyoda, Mariko Sugiyama, Masaharu Akita, Koji Kurihara
Publikováno v:
Journal of Toxicological Sciences. 43(12):751-768
The Organisation for Economic Co-operation and Development (OECD) Test Guideline (TG) 439 is an in vitro test method of reconstructed human epidermis (RhE), which was developed for hazard identification of irritating chemicals in accordance with a pr
Autor:
Akemi Toyoda1,2 a-toyoda@pola.co.jp, Maki Sugiyama1, Seiichiro Furihata1, Keiji Nishizumi1, Takashi Omori3, Hiroshi Itagaki2
Publikováno v:
Journal of Toxicological Sciences. Oct2017, Vol. 42 Issue 5, p569-577. 9p.
Autor:
Kenji Okamoto, Shinichi Watanabe, Shiho Fukui, Daisuke Sekiya, Takao Ashikaga, Toshihiko Kasahara, Noriyasu Imai, Masaharu Fujita, Masaaki Miyazawa, Hirokazu Seto, Miyuki Fujishiro, Yoshinao Kato, Akemi Toyoda, Osamu Takenouchi, Satoru Kurotani, Morihiko Hirota, Daiki Kyotani
Publikováno v:
Journal of Applied Toxicology. 35:1333-1347
The skin sensitization potential of chemicals has been determined with the use of the murine local lymph node assay (LLNA). However, in recent years public concern about animal welfare has led to a requirement for non-animal risk assessment systems f
Autor:
Shinichi Watanabe, Satoru Kurotani, Hirokazu Seto, Miyuki Fujishiro, Yoshinao Kato, Noriyasu Imai, Toshihiko Kasahara, Masaaki Miyazawa, Masaharu Fujita, Kenji Okamoto, Daisuke Sekiya, Shiho Fukui, Daiki Kyotani, Morihiko Hirota, Takao Ashikaga, Akemi Toyoda, Osamu Takenouchi
Publikováno v:
Journal of Applied Toxicology. 35:1318-1332
To develop a testing strategy incorporating the human cell line activation test (h-CLAT), direct peptide reactivity assay (DPRA) and DEREK, we created an expanded data set of 139 chemicals (102 sensitizers and 37 non-sensitizers) by combining the exi