Zobrazeno 1 - 6
of 6
pro vyhledávání: '"Akemi Kuromiya"'
Publikováno v:
Journal of Pharmacological Sciences, Vol 109, Iss 2, Pp 203-210 (2009)
Using ranirestat, an aldose reductase (AR) inhibitor, we investigated the relationship between sorbitol and fructose levels in the sciatic nerve and motor nerve conduction velocity (MNCV) in streptozotocin (STZ)-treated diabetic rats. Ranirestat inhi
Externí odkaz:
https://doaj.org/article/3a99e9e3535f4b8a9781b0b1d02cd7be
Publikováno v:
Journal of Pharmacological Sciences, Vol 107, Iss 3, Pp 231-237 (2008)
Ranirestat (AS-3201) is a novel aldose reductase (AR) inhibitor with potentially beneficial effects on diabetic sensorimotor polyneuropathy. In this study, we performed a kinetic analysis to determine the mode of inhibition of ranirestat on AR and in
Externí odkaz:
https://doaj.org/article/98fbf769cdbb4709b42a33ebc0baf8a2
Publikováno v:
Journal of Pharmacological Sciences, Vol 107, Iss 3, Pp 340-348 (2008)
We investigated the chronic functional and histopathological changes in the sciatic nerve and lens of streptozotocin (STZ)-diabetic rats and evaluated the preventive effects of ranirestat (AS-3201), a potent aldose reductase inhibitor, on these chang
Externí odkaz:
https://doaj.org/article/175beb06cfe24e73892c416d4ea4e89c
Publikováno v:
Journal of Pharmacological Sciences, Vol 109, Iss 2, Pp 203-210 (2009)
Using ranirestat, an aldose reductase (AR) inhibitor, we investigated the relationship between sorbitol and fructose levels in the sciatic nerve and motor nerve conduction velocity (MNCV) in streptozotocin (STZ)-treated diabetic rats. Ranirestat inhi
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b4ef7eb9d49622d9b0385529a981f5a0
https://doi.org/10.1254/jphs.08177fp
https://doi.org/10.1254/jphs.08177fp
Autor:
Kenji Suzuki, Jun-Ichi Matsumoto, Makoto Murata, Toshiyuki Negoro, Yoshiyuki Ono, Buichi Fujitani, Akemi Kuromiya, Masanobu Komiya, Ueda Shozo
Publikováno v:
Journal of Medicinal Chemistry. 41:4118-4129
A series of novel tetrahydropyrrolo[1,2-a]pyrazine derivatives were synthesized and evaluated as aldose reductase inhibitors (ARIs) on the basis of their abilities to inhibit porcine lens aldose reductase (AR) in vitro and to inhibit sorbitol accumul
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e9528354190fd338af75d0f5c468a2e4
https://doi.org/10.1021/jm9802968
https://doi.org/10.1021/jm9802968
Autor:
Buichi Fujitani, Jun-Ichi Matsumoto, Makoto Murata, Toshiyuki Negoro, Akemi Kuromiya, Kenji Suzuki, Yoshiyuki Ono, Masanobu Komiya, Ueda Shozo
Publikováno v:
ChemInform. 30
A series of novel tetrahydropyrrolo[1,2-a]pyrazine derivatives were synthesized and evaluated as aldose reductase inhibitors (ARIs) on the basis of their abilities to inhibit porcine lens aldose reductase (AR) in vitro and to inhibit sorbitol accumul
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::512bdb8cec62e9730ccb4f61dfdf1b3b
https://doi.org/10.1002/chin.199911179
https://doi.org/10.1002/chin.199911179